Giusy Matzeu
Dublin City University
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Publication
Featured researches published by Giusy Matzeu.
Analytical Methods | 2016
Giusy Matzeu; Conor O'Quigley; Eoghan McNamara; Claudio Zuliani; Cormac Fay; Tom Glennon; Dermot Diamond
The ability to non-invasively monitor sodium levels in sweat is of significant importance. Sodium is one of the preferred markers to diagnose and track the progression of cystic fibrosis, and knowledge of sodium levels could potentially enable personalised hydration strategies to be implemented for athletes or people working under severe environmental conditions. Herein we present a novel approach for the realisation of disposable potentiometric strips that allow for real-time monitoring of sodium in sweat. Our platform consists of a Solid-Contact Ion-Selective Electrode (SC-ISE) for Na+ detection and of a liquid-junction-free Reference Electrode (RE), combined together on a dual screen-printed substrate. Different poly-3,4-ethylenedioxythiophene (PEDOT) based films were tested as solid-contact, showing a significant impact on sensor characteristics such as sensitivity (i.e. differing from sub-Nernstian to Nernstian), dynamic range (i.e. 10−5 to 10−2.5 or 10−5 to 10−1aNa+), and especially within-batch reproducibility. The SC-ISE/RE combination was integrated into a microfluidic chip that was tested and optimised via on-bench trials. The Potentiometric Microfluidic Chip (PotMicroChip) was then connected to a wireless electronic platform to realise a wearable device whose performance was assessed during real-time stationary cycling sessions.
IEEE Transactions on Biomedical Engineering | 2016
Giusy Matzeu; Cormac Fay; Alix Vaillant; Shirley Coyle; Dermot Diamond
A feasibility study on a new technique capable of monitoring localized sweat rate is explored in this paper. Wearable devices commonly used in clinical practice for sweat sampling (i.e., Macroducts) were positioned on the body of an athlete whose sweat rate was then monitored during cycling sessions. The position at which the sweat fills the Macroduct was indicated by a contrasting marker and captured via a series of time-stamped photos or a video recording of the device during an exercise period. Given that the time of each captured image/frame is known (either through time stamp on photos or the constant frame rate of the video capture), it was, therefore, possible to estimate the sweat flow rate through a simple calibration model. The importance of gathering such valuable information is described, together with the results from a number of exercise trials to investigate the viability of this approach.
Talanta | 2014
Claudio Zuliani; Giusy Matzeu; Dermot Diamond
Liquid-junction-free reference electrodes have been prepared on screen printed substrates using poly-3,4-ethylenedioxythiophene (PEDOT) as solid-contact and novel ionogels as capping membrane. The chemico-physical properties of the PEDOT layer were tuned by changing the electropolymerization media and the electrodeposition technique. Electrodepositing PEDOT films potentiostatically or potentiodynamically were found to have a significant impact on the stability of the electrodes during the conditioning step. Optimization of the capping membrane formulation, e.g., acrylate monomers, ionic liquid, cross-linkers and photo-initiators, produced electrodes with properties almost equivalent with a commercial reference electrode. Thus, calibration plots of Na(+) ion-selective electrodes against the optimized solid-contact ionogel reference electrodes (SCI-REs) or against a double-liquid junction Ag/AgCl electrode did not present any significant difference. Such SCI-REs may provide an effective route to the generation of future low-cost components for potentiometric sensing strips.
Advances in Science and Technology | 2012
Giusy Matzeu; Claudio Zuliani; Dermot Diamond
Solid-contact Ion Selective Electrodes (SC-ISEs) for the detection of lead are prepared on screen printed substrates in order to have low-cost and disposable sensors which may be useful in long-term environmental monitoring. It is shown that the materials used as solid contact layer, the deposition techniques and their thickness affect greatly the performances of the sensors. Poly(3-octylthiophene-2,5-diyl) (POT) and poly-3,4-ethylenedioxithiophene (PEDOT) are employed in this investigation. A trend showing an optimum is found for sensors prepared with POT as the batch reproducibility depends on the amount drop-cast, i.e., thickness. In case of PEDOT which is grown amperometrically the trend is more complex but an optimum for the batch reproducibility is again found depending on the current density. In the latter case, the film thickness and the overoxidation degree of the polymer probably concur in determining a more complex relationship.
Reference Module in Materials Science and Materials Engineering#R##N#Comprehensive Materials Processing | 2014
Claudio Zuliani; Vincenzo F. Curto; Giusy Matzeu; Kevin J. Fraser; Dermot Diamond
Low-power chemo- and biosensing devices capable of monitoring clinically important parameters in real time represent a great challenge in the analytical field because the issue of sensor calibration pertaining to keeping the response within an accurate calibration domain is particularly significant. Diagnostics, personal health, and related costs will also benefit from the introduction of sensors technology. In addition, with the introduction of Registration, Evaluation, Authorization, and Restriction of Chemical Substances regulation, unraveling the cause–effect relationships in epidemiology studies will be of outmost importance in order to help establish reliable environmental policies aimed at protecting the health of individuals and communities. For instance, the effect of low concentration of toxic elements is seldom investigated as physicians do not have means to access the data.
Advances in Science and Technology | 2014
Giusy Matzeu; Cormac Fay; Conor O’Quigley; Dylan Orpen; Simon Coleman; Andrew Kavanagh; Dermot Diamond
In recent years, there has been significant progress in a number of sensing technologies related to on-body measurements, such as platforms for monitoring respiration, heart rate, location and movement. In these cases, the sensing element (s) are based on highly effective transducers that are increasingly integrated into garments such that they are becoming innocuous to the user. In contrast, the area of on-body chemical sensing remains highly under-developed. In this paper, we will address the significant challenges that are inhibiting the practical realisation of reliable chemical sensors and biosensors capable of generating accurate data in real time.
Sensors and Actuators B-chemical | 2015
Giusy Matzeu; Larisa Florea; Dermot Diamond
Electrochimica Acta | 2012
Salzitsa Anastasova; Aleksandar Radu; Giusy Matzeu; Claudio Zuliani; Ulriika Mattinen; Johan Bobacka; Dermot Diamond
Electroanalysis | 2016
Tom Glennon; Conor O'Quigley; Margaret McCaul; Giusy Matzeu; Stephen Beirne; Gordon G. Wallace; Florin Stroiescu; Niamh O'Mahoney; Paddy White; Dermot Diamond
Electrochimica Acta | 2014
Claudio Zuliani; Giusy Matzeu; Dermot Diamond