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Dive into the research topics where Gordon Winter is active.

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Featured researches published by Gordon Winter.


Applied Radiation and Isotopes | 2011

Radiosynthesis of a new PSMA targeting ligand ([18F]FPy-DUPA-Pep)

Noeen Malik; Hans-Jürgen Machulla; Christoph Solbach; Gordon Winter; Sven N. Reske; Boris D. Zlatopolskiy

Due to the specificity of expression of PSMA (prostate specific membrane antigen) particularly in prostate cancer cells (e.g. LNCaP), numerous PSMA ligands have been synthesized until now. In the current study, we synthesized DUPA-Pep having 2-[3-(1,3-dicarboxypropyl)ureido]pentanedioic acid (DUPA) linked via 8-aminooctanoic acid to two phenylalanine residues and chose 6-[(18)F]fluoronicotinic acid 2,3,5,6-tetrafluorophenyl ester [(18)F]FPy-TFP as a prosthetic group for coupling. [(18)F]FPy-DUPA-Pep was obtained in a radiochemical yield of 48±0.9% (decay uncorrected) within 50 min with a chemical purity of >98%.


Nanoscale | 2014

Synthesis, characterization, and biodistribution of multiple 89Zr-labeled pore-expanded mesoporous silica nanoparticles for PET

Larissa Miller; Gordon Winter; Benjamin Baur; Barbara Witulla; Christoph Solbach; Sven N. Reske; Mika Lindén


Pharmaceuticals | 2014

Synthesis, Radiolabelling and In Vitro Characterization of the Gallium-68-, Yttrium-90- and Lutetium-177-Labelled PSMA Ligand, CHX-A''-DTPA-DUPA-Pep

Benjamin Baur; Christoph Solbach; Elena Andreolli; Gordon Winter; Hans-Jürgen Machulla; Sven N. Reske


Molecular Imaging and Biology | 2015

Radiofluorination of PSMA-HBED via Al 18 F 2+ Chelation and Biological Evaluations In Vitro

Noeen Malik; Benjamin Baur; Gordon Winter; Sven N. Reske; Ambros J. Beer; Christoph Solbach


European Journal of Nuclear Medicine and Molecular Imaging | 2013

Comment on Afshar-Oromieh et al.: PET imaging with a [68Ga]gallium-labelled PSMA ligand for the diagnosis of prostate cancer: biodistribution in humans and first evaluation of tumour lesions

Sven N. Reske; Gordon Winter; Benjamin Baur; Hans-Jürgen Machulla; Thomas Kull


Nanoscale | 2017

Quantitative and correlative biodistribution analysis of 89Zr-labeled mesoporous silica nanoparticles intravenously injected into tumor-bearing mice

Larissa Kramer; Gordon Winter; Benjamin Baur; Andrea J. Kuntz; Thomas Kull; Christoph Solbach; Ambros J. Beer; Mika Lindén


The Journal of Nuclear Medicine | 2011

68Ga-DOTA-DUPA-Pep as a new peptide conjugate for molecular imaging of prostate carcinoma

Gordon Winter; Boris D. Zlatopolskiy; Thomas Kull; Jens Bertram; Felicitas Genze; Gabriela Cudek; Hans-Jürgen Machulla; Sven N. Reske


Biomedizinische Technik | 2017

Session 2. Cells, materials and biochemistry I

Gordon Winter; Anja Vogt; Nusrat Jihan Begum; Christoph Solbach; Ambros J. Beer; Gerhard Glatting; Peter Kletting


The Journal of Nuclear Medicine | 2015

Zr-89-, Y-90- and Lu-177-labeling and biological testing of mesoporous silica based nanoparticles

Benjamin Baur; Larissa Kramer; Gordon Winter; Mika Lindén; Ambros J. Beer; Christoph Solbach


The Journal of Nuclear Medicine | 2014

Synthesis and labeling of CHX-A''-DTPA-DUPA-Pep with gallium-68, zirconium-89 and lutetium-177 for diagnosis and therapy of prostate cancer

Benjamin Baur; Elena Andreolli; Gordon Winter; Hans Jürgen Machulla; Sven N. Reske; Christoph Solbach

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