Gül Soylu Özler

Coexistence of Upper Airway Obstruction and Primary and Secondary Enuresis Nocturna in Children and the Effect of Surgical Treatment for the Resolution of Enuresis Nocturna

Objective. The aim of this study is to investigate the coexistence of upper airway obstruction (UAO) and primary enuresis nocturna (PEN) and secondary enuresis nocturna (SEN) in children. Besides, the efficacy of surgery on resolution of enuresis nocturna is evaluated. Materials and Methods. The children with PEN and SEN were included in the first group and investigated for UAO in the Department of Otorhinolaryngology. During the same period, children who had been planned for an operation to treat UAO over 5 years old were included in the second group and were evaluated in the Department of Urology for PEN and SEN before the operation. Results. A hundred patients completed the study (50 patients in Group 1, 50 patients in Group 2). According to the otolaryngologic examination, 20 of 25 PEN patients and 9 of 25 SEN patients also had UAO. The difference was statistically different (P < 0.05). The second group consisted of fifty patients on the surgery list for upper airway obstructive pathologies. Coexistence of PEN and SEN is found in 12 and 3 of children, respectively. These ratios were statistically significant (P < 0.05). The improvement rate of PEN and SEN after operation in the second group was 83.3% and 33.3%, respectively. The difference was statistically significant (P < 0.05). Conclusion. There is a strong relationship between PEN and UAO, but it cannot be declared for SEN patients. UAO should be kept in mind as a possible etiologic factor for PEN.

The Efficacy of Sucralfate and Chlorhexidine as an Oral Rinse in Patients with Recurrent Aphthous Stomatitis

Aim. In this study, we compared the efficacy of sucralfate suspension with chlorhexidine as an oral rinse in patients with recurrent aphthous stomatitis (RAS) in terms of pain relief and healing time. Materials and Methods. The subjects with a complaint of recurrent oral aphthous ulcers less than 1 cm in diameter on the first day of the occurrence of the ulcer and between 20 and 40 years were included in the study. Seventy patients completed the study. The patients were randomized into two groups as SCH group and CHX group. Changes in pain scores, healing time, and side effects of the treatments were evaluated. Results. The mean value of pain scores on the days after the treatment from the first day to the seventh day was significantly higher in CHX group than SCH group (P ≤ 0.05). On the seventh day after the treatment, the ulcers were completely reepithelialized in 23 patients in SCH group and in 19 patients in CHX group. The difference was statistically significant (P ≤ 0.05). In SCH group, the mean healing time of ulcers was 1.97 ± 1.56 days whereas it was 2.80 ± 3.00 days in CHX group. The difference was statistically significant (P ≤ 0.05). No side effects were recorded in either of the groups. Conclusion. Topical sucralfate suspension is an easy, safe, inexpensive, and effective treatment option for RAS to obtain pain relief and shorten the healing time of oral ulcers.

Quality of Sexual Life in Males with Allergic Rhinitis

DOI: 10.4328/JCAM.2602 Received: 03.06.2014 Accepted: 05.07.2014 Printed: 01.03.2016 J Clin Anal Med 2016;7(2): 155-7 Corresponding Author: Gül Soylu Özler, Mustafa Kemal University, Department of Otorhinolaryngology, Hatay, Türkiye. T.: +90 3262293323 GSM: +905053980778 E-Mail: soylugul@yahoo.com Özet Amaç: Bu çalışmanın amacı alerjik rinitli erkeklerin cinsel yaşam kalitesini değerlendirmektir. Gereç ve Yöntem: 40 deri prick testi ile tanı konmuş alerjik rinitli erkek hasta ile 40 alerjisi olmayan kontrol hastası çalışmayı tamamladı. Olguların cinsel yaşam kalitesi, uluslararası erektil fonksiyon anketi ile değerlendirildi. Bulgular: Alerjik rinitli grubun erektil fonksiyon, orgazmik fonksiyon, seksüel istek, ilişki tatmini, genel tatmin skorları kontrol grubuna göre daha düşük idi(p=0.0001). Tartışma: Alerjik rinitin yaşam kalitesi üzerine olumsuz etkileri vardır. Alerjik rinitin etkin tedavisi ile eşlik eden sosyal, cinsel ve uyku bozuklukları da önlenmiş olacaktır.

The Effect of Passive and Active Smoking on Nasal Mucociliary Clerarance Time

Aim: The aim of this study was to investigate the effect of passive and active smoking on NMC by comparing the results of age and sex matched healthy individuals, passive and active smokers. Material and Method: A total of 75 subjects met the criteria and were divided into three groups: control group (nonsmokers, group 1, n =25), passive smokers group(group 2, n =25), active smokers group (group 3, n =25). NMC of these subjects were measured and compared. Moreover, the amount of cigarette consumption of active smokers group were calculated as package to year and the correlation between NMC and the amount of cigarette consumption. in active smokers group were evaluated. Results: The mean NMC in passive smokers group and active smokers group were significantly longer than the control group (p=0,0001) The comparison of NMC values between the passive smokers group and the active smokers group revealed no statistically significant dif ferences (p≥0,05). There was positive correlation between the increase in NMC and amount of cigarette consumption in the active smokers group ( p=0,0001,r=0.433). Discussion: Both active and passive smoking prolonged nasal mucociliary clearance time when they were compared with healthy controls. Tobacco exposure is associated diseases such as asthma, chronic rhinosinusitis, and lower airway infections. It may be related to the direct effect of prolonged NMC.

Electron microscopic examination of effects of bogma raki and walnut on cochlea An experimental study

Illegal alcohol beverages known as bogma raki in our country are consumed widely in our region. The studies investigating the relationship between alcohol consumption and hearing ability report different results. In this study, we aimed to investigate the toxic effects of bogma raki that contains neurotoxic substances on cochlea by electron microscopy. To the best of our knowledge, this study is the first in the literature. A total of 48 Wistar male albino rats (aged 12–16 weeks and weighing 200–240 g) were used in the study. The rats were divided into 4 groups with 12 animals in each group. The groups include control, bogma raki, walnut, and walnut + bogma raki groups. Bogma raki (30% v/v, 9.2 ml kg−1 day−1) is added to drinking water of rats in bogma raki group (n = 12) for 4 weeks. Walnut group rats (n = 12) are fed with standard rat food and walnut without limitation (10 g kg−1 day−1). Bogma raki + walnut group rats (n = 12) are fed with standard rat food and walnut and bogma raki is added to drinking water. The cochleas were dissected and removed en bloc and examined by electron microscopy. Perineuronal oedema around neurons of spiral ganglion and hairy cells of organ of Corti were present in the bogma raki group, walnut group and bogma raki + walnut group under electron microscopic examination. Comparing these three groups, there were no differences in the ultrastructural pathological changes. In the ultrastructural examination of the myelinated axons forming cochlear nerve, no ultrastructural pathology was detected in all the groups.

Thyroid gland papillary microcarcinomas diagnosed by extraglandular mass findings

Thyroid papillary microcarcinomas not only present with neck lympathic metastasis but also may occur in thyroglossal cysts or ectopic thyroid glands. The aim of this case report is to discuss two cases of thyroid papillary carcinomas with no mass detectable by thyroid gland ultrasonography but diagnosed with the biopsy of cervical lymphatic metastasis and occurred in ground of lateral sided thyroglossal cyst. It must be kept in mind that, in cervical metastasis and even laterally sided cystic masses, these symptoms may be associated with thyroid papillary carcinoma.

Bukkal Bölgeden Kaynaklanan Pleomorfik Adenom: Olgu Sunumu

Tukuruk bezi tumorleri tum bas-boyun tumorlerinin %3-4’unu olusturmaktadir. Benign mikst tumor olarak da bilinen pleomorfik adenom tukuruk bezlerinin en sik gorulen benign tumorudur. En sik major tukuruk bezlerinde gorulur(%92). Minor tukuruk bezinden koken alan pleomorfik adenomlar en sik damakta gorulur, bunu ust dudak ve bukkal bolge takip etmektedir. Etyolojisi tam olarak bilinmemekle birlikte gunumuzde birlestirici kanalin epitel ve miyoepitel hucrelerine donusme kapasitesine sahip bagimsiz bir rezerv hucresinden kaynaklandigi dusunulmektedir. Nadiren malign transformasyon gosterebilir ve siklikla uzun suredir var olan tumorlerde gorulur. Bu durum tanidan sonraki ilk 5 yil icerisinde %1,5 iken,15 yili astiginda risk %10 olmaktadir. Bu olgu sunumunda 15 yildir bukkal bolgede yerlesen pleomorfik adenom olgusu sunulacaktir.

Relationship of Recurrent Aphthous Stomatitis with Nutritional Habits

Aim: In this study we investigated the frequency and relationship of recurrent aphthous stomatitis(RAS) with family history, personal variables such as weight, heigt, antibiotic usage, teeth brush and nutritional habits in geriatric patients. Material and Method: The patients over 65 years old were included in the study. Before examination, the definition of recurrent oral aphthous ulcers and a visual informatory form including photographs were presented to the subjects. The age, sex, height, weight of the subjects were noted on a chart. Then the history of recurrent oral aphthous ulcerations were asked and if present the frequency of the ulcers, the type of the ulcers, the localization of the ulcers, the subjective symptome of the ulcers, familial history for the ulcers, frequency of antibiotic usage, teeth brush habits and nutritional habits were examined by a questionnaire. Results: Eighty subjects completed the study. 31.25% of subjects declared recurrent oral ulcer history. Pain was the leading subjective symptome declared by 44% of the subjects. 15% of the subjects had a family history for recurrent oral ulcers. There was no correlation between frequency of antibiotic usage and history of RAS. Also, there was no correlation between teeth brush habits and history of RAS. The RAS group consumed tea and fizzdrinks more frequently whereas they consumed milk and milk products, walnut, bread and other grains more rarely. Discussion: Nutritional habits may have a role on ocurrence of reccurrent oral aphthous ulcerations. So we are of the opinion that the elimination of the risky nourishments and the addition of the protective nourishments may be the first step of the treatment period.

Does Halitosis Effect Sexual Life in Males

Aim: Halitosis is an unpleasant alteration of the halitus. The aim of the study is to assess the quality of sexual life of males with and without halitosis. Material and Method: Males between 20-50 years old; with a complaint of halitosis; married and able to complete the study were included in the study. The control group were healthy, adult, married males who have normal otorhinolaryngologic examination. The International Index of Erectile Function questionnaire(IIEF) were used to assess the quality of sexual life of males with halitosis and the results were compared with a similar group of healthy men. Results: A total of 80 adult subjects completed the study. When the groups were compared in terms of age, body mass index(BMI) and duration of marriage, they were similar (p=0.65, p= 0.20, p= 0.08 respectively). The halitosis group had significantly lower scores for all function domains (p=0.0001).There was no correlation between degree of halitosis and the scores of IIEF (p< 0.05). Discussion: This is the first study investigating the sexual health of males with halitosis. Halitosis not only effects oral health status but also strongly declines quality of life. The otorhinolaryngologist must not only treat halitosis but also help the patient to stand up to social and sexual problems concomitting halitosis.

Determination of oxidative stress and effect of erdosteine on rhinitis medicamentosa in a rat model

We aimed to determine the presence of oxidative stress in rhinitis medicamentosa (RM) and to evaluate the effect of erdosteine (ED) on mucosal changes in a rat model. Twenty-four male rats were used in this experimental study. Three groups were created. Group 1 (n=8) was the control group. Two puffs of 0.05% oxymetazolin were sprayed into the nasal cavities of the remaining rats (n=16) three times daily for eight weeks. One of these 16 rats was scarified at the end of the eight weeks and examined to confirm the presence of RM. Seven of the remaining 16 rats were killed, and venous blood samples were taken (Group 2). Group 3 (n=8) received 10mg/kg of an ED suspension orally for seven days. All rats were put on formalin for light microscopy. The total antioxidant status (TAS) was similar in all groups (p=0.073). The total oxidative status (TOS) of the RM group was significantly higher than that of the control group and RM+ED group (Group 3) (p=0.003 and p=0.011, respectively). The pathological recovery of the nasal mucosa of the rats was similar in the RM+ED and control groups. The TOS was high in this RM rat model, and oxidative stress was associated with RM. ED significantly ameliorated nasal mucosal changes induced by RM, suggesting that oxidative stress may play an important role in the pathophysiology of this condition.