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Featured researches published by Güven Çetin.
European Journal of Cardio-Thoracic Surgery | 1997
Soysal O; Nurettin Karaoglanoglu; Demiracan S; Salih Topcu; Irfan Tastepe; Sadi Kaya; Unlü M; Güven Çetin
OBJECTIVE Surgery can only offer palliation in an attempt to slow the progression of malignant pleural mesothelioma (MPM). We want to assess the effectiveness and safety of pleurectomy/decortication in establishing a tissue diagnosis, and controlling pleural fluid accumulation and symptoms in patients with MPM. METHODS We reviewed our pleurectomy results in 100 patients with MPM over a 19 year period. Major symptoms were chest pain, cough and dyspnea, and radiographic findings included pleural mass, pleural fluid and constriction of involved hemithorax. RESULTS Approximately two thirds of the patients underwent surgery prior to tissue diagnosis. Eighty-nine patients had stage I and stage II disease, 8 and 81%, respectively. The patients underwent subtotal (44%) or total pleurectomy (56%). The surgical mortality rate was 1% (1/100) and the morbidity rate was 22%. Morbidity included prolonged air leak (n = 12), empyema (n = 6), reaccumulation of pleural fluid (n = 2) and wound infection (n = 2). Palliative results included dyspnea and cough relief in all patients, chest relief in 60 (85%) and pleural fluid control in 52 (96%) patients. Median survival was 17 months in MPM patients. CONCLUSIONS We conclude that pleurectomy/decortication safely provides both tissue diagnosis and effective of pleural effusion and symptoms and therefore excellent palliation in patients with MPM.
The Annals of Thoracic Surgery | 2003
Tamer Altinok; Salih Topcu; A.Irfan Tastepe; Ülkü Yazıcı; Güven Çetin
BACKGROUND Localized fibrous tumors of the pleura, which are considered to originate from submesothelial connective tissue, are rare. The purpose of this study was to investigate the clinical features of these tumors and to determine the optimal treatment and follow-up. METHODS The records of 10 consecutive patients with localized fibrous tumors of the pleura operated on at the Ataturk Center for Chest Diseases and Thoracic Surgery between 1995 and 2001 were retrospectively reviewed. Diagnostic procedures, clinical courses, and outcomes of these patients were studied. Total excision through a thoracotomy was performed in all of the patients. Pneumonectomy was required in 1 patient because of a giant intraparenchymal localized fibrous tumor of the pleura. Additional partial chest wall resections were done in 2 patients. RESULTS The size of excised tumors ranged from 10 x 8 x 4 cm to 30 x 25 x 20 cm. Malignant transformation was seen in 1 patient 22 months after resection of a benign tumor. Four cases were pathologically considered to be malignant. All patients except 1 are alive (follow-up 16 to 57 months after resection). CONCLUSIONS Although localized fibrous tumors of the pleura are considered histologically benign tumors, because of the risk of recurrence and malignant transformation, complete surgical resection is indicated and long-term follow-up is recommended in all patients.
Canadian Respiratory Journal | 2000
Salih Topcu; Ayşin Alper; Erkmen Gülhan; Osman Koçyigit; Irfan Tastepe; Güven Çetin
OBJECTIVES To analyze retrospectively 60 patients (13 infants and children, 47 adults--21 men and 39 women) with mediastinal neurogenic tumours admitted to Atatürk Centre for Chest Disease and Chest Surgery, Ankara, Turkey between 1988 and 1999. This comprised 21.2% of 283 patients who had surgical operations for all mediastinal masses during the same period. PATIENTS AND METHODS The patients ranged from four to 67 years of age. Thirteen patients were younger than 15 years and 47 were 15 years of age or older. Medical records were reviewed for demographic data, clinical presentation, diagnostic investigations, operative procedures, and tumour location and invasion. Postoperative morbidity and mortality were noted as well as long term follow-up. The clinical investigations included chest x-ray and computed tomography of the thorax in all patients, and spinal magnetic resonance imaging and bronchoscopical examination in some. Clinical variables were compared. RESULTS The tumours had the following characteristics: 42 (70%) were nerve sheath tumours; 15 (25%) were autonomic ganglion tumours; two (3.6%) were paragangliomas; and one (1.4%) was a malignant peripheral neuroectodermal tumour (Askins tumour). Nerve cell tumours comprised the majority of tumours in infants and children (nine of 13, 69%), whereas the nerve sheath tumours were most frequent in adults (39 of 47, 83%). There were 48 benign and 12 (20%) malignant tumours when all age groups were considered; the malignancy rate was 61.5% (eight of 13) in children and 8.5% (four of 47, P<0.05) in adults. All patients were operated via a posterolateral thoracotomy. Surgical resection of the tumour was complete in 56 of 60 patients (93.3%). Resection of malignant tumours was grossly incomplete in four cases (four of 12, 33.3%). All benign tumours were totally excised. There were two major complications (respiratory failure and pulmonary emboli) and 14 minor complications in the perioperative period. The mean follow-up period was five years and seven months. Tumours recurred in 5.3% (three of 56) of patients who had a complete resection initially. There were no late deaths related to benign tumours. CONCLUSIONS Complete resection of tumours can be performed safely by a thoracotomy approach and is important for achieving satisfactory long term survival in most mediastinal neurogenic tumours.
World Journal of Surgery | 2005
Mehmet Sırmalı; Hasan Türüt; Suat Gezer; Göktürk Fındık; Sadi Kaya; Ýrfan Tastepe; Güven Çetin
The limited number of publications on repair of the foramen of Morgagni hernia concentrates mainly on the laparotomy approach. We present our experience with the transthoracic approach. Patients who were diagnosed as having a foramen of Morgagni hernia and were operated on via the transthoracic approach between December 1991 and June 2004 are reviewed retrospectively for their age, sex, presenting symptoms, and diagnostic and surgical procedures. Surgical repair was carried out via the transthoracic approach in all cases. Of the 24 patients who underwent transthoracic diaphragmatic repair of the defect, 16 were women and 8 were men, with an overall mean age of 55.1 years (range 42–69 years). In most cases the defect was on the right side; there was only one case of a left-sided defect. The most common presenting symptoms were dyspnea and gastrointestinal discomfort; five (20.8%) patients were asymptomatic. In 21 cases (87.5%) the diagnoses were established radiologically. The defect was accessed surgically via a posterolateral thoracotomy. No postoperative morbidity or mortality was observed. The mean follow-up was 8.3 years (14 months to 14 years), and no recurrence was noted. As important as the surgical repair of the foramen of Morgagni hernia itself is selection of the surgical approach so adhesions of the hernial sac from the surrounding tissues in the thoracic cavity are easily released. The transthoracic approach is amenable to safe primary repair of the defect and the release of adhesions, even in elderly and obese patients, in whom adhesions may be excessive.
European Journal of Cardio-Thoracic Surgery | 2000
Irfan Tastepe; Ayşin Alper; Hatice Esra ÖzaydIn; Leyla Memis; Güven Çetin
We report a patient with two synchronous distinct masses in the same hemithorax both of which got the diagnosis of benign localized fibrous tumor of the pleura. The plain chest X-ray was rather obscured due to a large left-sided pleural effusion, but her subsequent computerized chest tomography revealed a heterogeneous hypodense soft tissue mass, which was pleural in origin, sitting on the diaphragm bathed in fluid. At thoracotomy, we detected two distinct masses in the left hemithorax, both arising from the visceral pleura via their vascular pedicles.
Scandinavian Cardiovascular Journal | 1994
Sadi Kaya; Irfan Tastepe; Melih Kaptanoglu; Mustafa Yuksel; Salih Topcu; Güven Çetin
A retrospective review is presented of 20 cases with resection of intrathoracic goitre between 1975 and 1993. The mean age of the 11 men and nine women was 53 years. The intrathoracic goitre was primary in seven cases and secondary in 13. The presenting clinical features and the pathology, surgical risks and optimal approaches are discussed. Primary intrathoracic goitre should be approached via a thoracotomy, because of the independent vascular supply. As secondary intrathoracic goitres are supplied by vascular pedicles arising from the inferior thyroid artery, a cervical collar incision is preferable. In the event of significant mediastinal bleeding, which is difficult to control from a cervical incision, a T-shaped incision for partial or full sternotomy can be performed, or even thoracotomy.
European Journal of Cardio-Thoracic Surgery | 1998
Abdullah Irfan Tastepe; İsmail Cüneyt Kurul; Sedat Demircan; Şerife Tuba Liman; Sadi Kaya; Güven Çetin
OBJECTIVE Typical bronchial carcinoids are very low grade neuroendocrine neoplasm of the tracheobronchial tree and have very good results in surgical treatment. Surgical treatment varies from bronchotomy-excision to major resective procedures. We presented our results of bronchotomy, simple excision and long-term follow-up. METHODS In Atatürk Centre for Chest Disease and Chest Surgery, 16 patients with bronchial carcinoid tumour underwent bronchotomy-excision over a 23-year-period. In all of the cases tumours were in polypoid type. Except these 16 cases 51 patients with bronchial carcinoids underwent operations in the same period. Presenting symptoms were haemoptysis, cough, recurrent pulmonary infection, dyspnea and chest pain. Rigid bronchoscopies were performed on all of the patients preoperatively for diagnosis of the tumour and to determine the surgical procedure and we performed control bronchoscopies on all of the patients in their follow-up period. RESULTS Patients were checked for periods ranging from 2 to 23 years both radiologically and bronchoscopically. We did not find any recurrences and death related to surgery and morbidity rate were minimal. CONCLUSION We think that bronchotomy and simple excision are effective and safe procedures for the treatment of bronchial carcinoid tumours with low morbidity in selected cases like polypoid type lesions and have as good a long-term survival rate as the other surgical treatment methods have.
Scandinavian Cardiovascular Journal | 1996
M E Balkan; Ali Özdülger; Irfan Tastepe; Sadi Kaya; Güven Çetin
In minitracheotomy, a relatively simple percutaneous technique for tracheal cannulation, a small-bore tube is inserted via the cricothyroid membrane to provide access to suction removal of excess secretion or aspirated material from the tracheobronchial tree. It allows efficient tracheobronchial toilet while preserving glottic function and avoiding the disadvantages of conventional tracheostomy and endotracheal intubation. The indications for minitracheotomy in 20 cases were excessive postoperative or postpneumonic secretion (14), difficulty with endotracheal suction (5) and acute airway obstruction (1). The only major complication was bleeding in one case. Minor bleeding occurred at the incision in two cases. The cannula was retained for 3-8 days and removal was followed by closure within 48 hours. There were no adverse laryngeal effects. Minitracheotomy was well tolerated by the patients and is a useful adjunct for removal of airway secretion and hospitalized patients.
Respirology | 2007
Hasan Türüt; Irfan Tastepe; Sadi Kaya; Mehmet Sırmalı; Suat Gezer; Gürhan Öz; Göktürk Fındık; Güven Çetin
Background and objective: This study reports on the demographic features, clinico‐pathological results and prognoses of patients aged less than 36 years diagnosed with non‐small cell lung cancer (NSCLC).
The Japanese Journal of Thoracic and Cardiovascular Surgery | 2002
Funda Demirag; Salih Topcu; İ.Cüneyt Kurul; Leyla Memis; Güven Çetin
Benign fibrous histiocytoma of the trachea is a rare neoplasm. We reported 2 cases, one aged 3 years and one 5 years, with endotracheal fibrous histiocytoma showing no clinical evidence of malignancy. Two segments of the trachea were resected and an end-to-end anastomosis was done in 1 case and circular resection of the left bronchi and carinoplasty for the other. Pathologically, both tumors consisted of spindle cells arranged in storiform and fascicular patterns. Immunohistochemically, tumor cells stained for vimentin and CD68 but were negative for P53. These cellular features and immunohistochemical findings indicate benign fibrous histiocytoma of the trachea. No recurrence was seen.