Guy Madison

Variability in isochronous tapping: higher order dependencies as a function of intertap interval.

Isochronous serial interval production (ISIP) data, as from unpaced finger tapping, exhibit higher order dependencies (drift). This fact has largely been ignored by the timing literature, one reason probably being that influential timing models assume random variability. Men and women, 22-36 years old, performed a synchronization-continuation task with intertap intervals (ITI) from 0.4 s to 2.2 s. ISIP variability was partitioned into components attributable to drift and 1st-order serial correlation, and the results indicate that (a) drift contributes substantially to the dispersion for longer ITIs, (b) drift and 1st-order correlation are different functions of the ITI, and (c) drift exhibits break close to 1.0 s and 1.4 s ITI. These breaks correspond to qualitative changes in performance for other temporal tasks, which suggests common timing processes across modalities and tasks.

Practice Does Not Make Perfect No Causal Effect of Music Practice on Music Ability

The relative importance of nature and nurture for various forms of expertise has been intensely debated. Music proficiency is viewed as a general model for expertise, and associations between deliberate practice and music proficiency have been interpreted as supporting the prevailing idea that long-term deliberate practice inevitably results in increased music ability. Here, we examined the associations (rs = .18–.36) between music practice and music ability (rhythm, melody, and pitch discrimination) in 10,500 Swedish twins. We found that music practice was substantially heritable (40%−70%). Associations between music practice and music ability were predominantly genetic, and, contrary to the causal hypothesis, nonshared environmental influences did not contribute. There was no difference in ability within monozygotic twin pairs differing in their amount of practice, so that when genetic predisposition was controlled for, more practice was no longer associated with better music skills. These findings suggest that music practice may not causally influence music ability and that genetic variation among individuals affects both ability and inclination to practice.

Intelligence and Variability in a Simple Timing Task Share Neural Substrates in the Prefrontal White Matter

General intelligence is correlated with the mean and variability of reaction time in elementary cognitive tasks, as well as with performance on temporal judgment and discrimination tasks. This suggests a link between the temporal accuracy of neural activity and intelligence. However, it has remained unclear whether this link reflects top-down mechanisms such as attentional control and cognitive strategies or basic neural properties that influence both abilities. Here, we investigated whether millisecond variability in a simple, automatic timing task, isochronous tapping, correlates with intellectual performance and, using voxel-based morphometry, whether these two tasks share neuroanatomical substrates. Stability of tapping and intelligence were correlated and related to regional volume in overlapping right prefrontal white matter regions. These results suggest a bottom-up explanation of the link between temporal stability and intellectual performance, in which more extensive prefrontal connectivity underlies individual differences in both variables.

Musical intervention for patients with dementia: a meta-analysis.

AIMS AND OBJECTIVES To provide a meta-analysis of the effects of music interventions on patients with dementia, separating, for the first time, between different types of interventions and different outcome measures, namely affective, behavioural, cognitive and physiological. BACKGROUND Music therapy is an attractive form of intervention for the growing number of demented patients, for whom pharmacological interventions are not always effective and may lead to undesired side effects. While music is more frequently applied in clinical settings for each year, no meta-analysis has considered effects of music interventions on affective, behavioural, cognitive and physiological outcomes separately. DESIGN A standard meta-analysis approach was applied. METHODS We include all original studies found for the key words music and dementia. Mean effect sizes and confidence intervals are computed from study effect sizes according to standard methods, and these are considered for various common types of music interventions separately. RESULTS Nineteen studies with a total of 478 dementia patients exhibit effect sizes ranging from 0·04-4·56 (M = 1·04). Many of these indicate large positive effects on behavioural, cognitive and physiological outcome measures, and medium effects on affective measures. CONCLUSIONS Music interventions seem to be effective and have the potential of increasing the quality of life for patients with dementia. Many studies in this area suffer from poor methodological quality, which limits the reach of meta-analysis and the strength and generalisability of these conclusions. RELEVANCE TO CLINICAL PRACTICE Being inexpensive and largely without adverse side effects, current knowledge seems to indicate that music interventions can be recommended for patients in all stages of dementia.

Human sensorimotor tracking of continuous subliminal deviations from isochrony

We show that people continuously react to time perturbations in the range 3-96 ms in otherwise isochronous sound sequences. Musically trained and untrained participants were asked to synchronize with a sequence of sounds, and these two groups performed almost equally below the threshold for conscious detection of the perturbations. Above this threshold the motor reactions accounted for a larger proportion of the stimulus deviations in musically trained participants.

Fractal modelling of isochronous serial interval production

Abstract.The Hurst exponent (H) was estimated for series of 256 time intervals produced by human participants, collected in 5 sessions performed on different days. Each series was obtained during the continuation phase following synchronization with 25 isochronous intervals generated by a computer and presented through headphones. Dispersional analysis yielded estimates of H > 0.5. These were sufficiently stable to yield statistically significant differences between participants and between each target interval duration (0.5, 0.8, 1.1, and 1.5 s). The results indicate that variability in isochronous serial interval production (ISIP) can be modeled as fractional Gaussian noise, which corroborates and qualifies previous research indicating positive serial dependency or long memory in ISIP data in terms of drift and 1/f noise characteristics. It is concluded that ISIP is a more complex process than is assumed by influential timing models and theories, and that realistic modeling of human timing must account for nonlinear variability patterns.The Hurst exponent (H) was estimated for series of 256 time intervals produced by human participants, collected in 5 sessions performed on different days. Each series was obtained during the continuation phase following synchronization with 25 isochronous intervals generated by a computer and presented through headphones. Dispersional analysis yielded estimates of H > 0.5. These were sufficiently stable to yield statistically significant differences between participants and between each target interval duration (0.5, 0.8, 1.1, and 1.5 s). The results indicate that variability in isochronous serial interval production (ISIP) can be modeled as fractional Gaussian noise, which corroborates and qualifies previous research indicating positive serial dependency or long memory in ISIP data in terms of drift and 1/f noise characteristics. It is concluded that ISIP is a more complex process than is assumed by influential timing models and theories, and that realistic modeling of human timing must account for nonlinear variability patterns.

Differences in regional brain volume related to the extraversion-introversion dimension—A voxel based morphometry study

Extraverted individuals are sociable, behaviorally active, and happy. We report data from a voxel based morphometry study investigating, for the first time, if regional volume in gray and white matter brain regions is related to extraversion. For both gray and white matter, all correlations between extraversion and regional brain volume were negative, i.e. the regions were larger in introverts. Gray matter correlations were found in regions that included the right prefrontal cortex and the cortex around the right temporo-parietal junction--regions that are known to be involved in behavioral inhibition, introspection, and social-emotional processing, e.g. evaluation of social stimuli and reasoning about the mental states of others. White matter correlations extended from the brainstem to widespread cortical regions, and were largely due to global effects, i.e. a larger total white matter volume in introverts. We speculate that these white matter findings may reflect differences in ascending modulatory projections affecting cortical regions involved in behavioral regulation.

Intelligence and temporal accuracy of behaviour : unique and shared associations with reaction time and motor timing

Intelligence is associated with accuracy in a wide range of timing tasks. One source of such associations is likely to be individual differences in top-down control, e.g., sustained attention, that influence performance in both temporal tasks and other cognitively controlled behaviours. In addition, we have studied relations between intelligence and a simple rhythmic motor task, isochronous serial interval production (ISIP), and found a substantial component of that relation, which is independent of fluctuations in top-down control. The main purpose of the present study was to investigate whether such bottom-up mechanisms are involved also in the relation between intelligence and reaction time (RT) tasks. We thus investigated whether common variance between the ISIP and RT tasks underlies their respective associations with intelligence. Two hundred and twelve participants performed a simple RT task, a choice RT task and the ISIP task. Intelligence was assessed with the Raven SPM Plus. The analysed timing variables included mean and variability in the RT tasks and two variance components in the ISIP task. As predicted, RT and ISIP variables were associated with intelligence. The timing variables were positively intercorrelated, and a principal component analysis revealed a substantial first principal component that was strongly related to all timing variables, and positively correlated with intelligence. Furthermore, a commonality analysis demonstrated that the relations between intelligence and the timing variables involved a commonality between the timing variables as well as unique contributions from choice RT and ISIP. We discuss possible implications of these findings and argue that they support our main hypothesis, i.e., that relations between intelligence and RT tasks have a bottom-up component.

Genetic pleiotropy explains associations between musical auditory discrimination and intelligence.

Musical aptitude is commonly measured using tasks that involve discrimination of different types of musical auditory stimuli. Performance on such different discrimination tasks correlates positively with each other and with intelligence. However, no study to date has explored these associations using a genetically informative sample to estimate underlying genetic and environmental influences. In the present study, a large sample of Swedish twins (N = 10,500) was used to investigate the genetic architecture of the associations between intelligence and performance on three musical auditory discrimination tasks (rhythm, melody and pitch). Phenotypic correlations between the tasks ranged between 0.23 and 0.42 (Pearson r values). Genetic modelling showed that the covariation between the variables could be explained by shared genetic influences. Neither shared, nor non-shared environment had a significant effect on the associations. Good fit was obtained with a two-factor model where one underlying shared genetic factor explained all the covariation between the musical discrimination tasks and IQ, and a second genetic factor explained variance exclusively shared among the discrimination tasks. The results suggest that positive correlations among musical aptitudes result from both genes with broad effects on cognition, and genes with potentially more specific influences on auditory functions.

Genetic and Environmental Influences on the Relationship between Flow Proneness, Locus of Control and Behavioral Inhibition

Flow is a psychological state of high but subjectively effortless attention that typically occurs during active performance of challenging tasks and is accompanied by a sense of automaticity, high control, low self-awareness, and enjoyment. Flow proneness is associated with traits and behaviors related to low neuroticism such as emotional stability, conscientiousness, active coping, self-esteem and life satisfaction. Little is known about the genetic architecture of flow proneness, behavioral inhibition and locus of control – traits also associated with neuroticism – and their interrelation. Here, we hypothesized that individuals low in behavioral inhibition and with an internal locus of control would be more likely to experience flow and explored the genetic and environmental architecture of the relationship between the three variables. Behavioral inhibition and locus of control was measured in a large population sample of 3,375 full twin pairs and 4,527 single twins, about 26% of whom also scored the flow proneness questionnaire. Findings revealed significant but relatively low correlations between the three traits and moderate heritability estimates of .41, .45, and .30 for flow proneness, behavioral inhibition, and locus of control, respectively, with some indication of non-additive genetic influences. For behavioral inhibition we found significant sex differences in heritability, with females showing a higher estimate including significant non-additive genetic influences, while in males the entire heritability was due to additive genetic variance. We also found a mainly genetically mediated relationship between the three traits, suggesting that individuals who are genetically predisposed to experience flow, show less behavioral inhibition (less anxious) and feel that they are in control of their own destiny (internal locus of control). We discuss that some of the genes underlying this relationship may include those influencing the function of dopaminergic neural systems.