Hajime Yoshikoshi

Synthesis of (+)-trans-Whisky Lactone, (+)-trans-Cognac Lactone and (+)-Eldanolide

A new and useful synthesis of (+)-trans-whisky lactone (3), (+)-trans-cognac lactone (4) and (+)-eldanolide (5) starting from levoglucosenone (1) is described

Synthesis of (+)-trans-whisky lactone, (-)-cis-whisky lactone, (+)-cognac lactone and (+)-eldanolide

(+)-trans-Whisky lactone (5) and (-)-cis-whisky lactone (8), (+)-cognac lactone (9) and (+)-eldanolide (10) were synthesized starting from levoglucosenone (1) in optically pure states