Hande Ezerarslan

Presence of vascular loops entering internal acoustic channel may increase risk of Sudden sensorineural hearing loss and reduce recovery of these patients.

To analyze whether there is correlation between branching patterns of anterior inferior cerebellar artery/posterior inferior cerebellar artery (AICA/PICA) in cerebellopontine angle (CPA) area, as demonstrated by three‐dimensional fast imaging employing steady‐state acquisition (3D FIESTA) magnetic resonance imaging (MRI) and 1) idiopathic sudden sensorineural hearing loss (ISSNHL) outcomes and 2) recovery of ISSNHL.

Giant Thyroid Nodule Atypically Located in The Carotid Triangle of The Neck: A Case Report

DOI: 10.4328/JCAM.586 Received: 17.01.2011 Accepted: 02.03.2011 Printed: 01.05.2016 J Clin Anal Med 2016;7(3): 402-4 Corresponding Author: Guclu Kaan Beriat, Ufuk Universitesi Tip Fakultesi Dr. Ridvan Ege Hastanesi Kulak Burun Bogaz Anabilimdali, Balgat, 06520, Ankara, Turkiye. T.: +90 3122044175 F.: +90 3122847786 E-Mail: beriat4@gmail.com Ozet Ektopik tiroid dokusu tiroid dokusunun anormal migrasyonuyla olusan nadir gorulen bir tiroid patolojisidir. Yaklasik olarak 100,000-300,000 dogumda bir gorulur ve genellikle asemptomatiktir. Tiroid doku hiperplazisine bagli olarak, asemptomatik ektopik tiroid dokusu buyuyerek boyun kitlesi seklinde semptomatik hale gelebilir. Trakea onundeki normal lokalizasyonu disinda tiroid bezi, dil koku ile trakea arasinda genellikle orta hatta herhangi bir seviyede gorulebilir. 71 yasinda erkek hasta, boyun sag tarafinda, sag karotid ucgende 5x4x3 cm boyutlarinda kitle ile kulak burun bogaz poliklinigimize basvurdu. Yapilan ince igne aspirasyon biyopsisi sonucu tiroid dokusu olarak rapor edildi ve takiben kitle genel anestezi altinda eksize edildi. Yapilan patolojik degerlendirmesi sonucunda kitlenin atipik olarak yerlesim gosteren ektopik yerlesimli tiroid nodulu oldugu anlasildi. Hastanin yapilan bir yillik takibinde herhangi bir komplikasyonla karsilasilmadi.

The Evaluation of Relationship Between the Adiponectin and Laryngopharyngeal Reflux Desease ( A Preliminary Report)

Aim The aim of our study is to identify etiopathology of Laryngopharyngeal Reflux (LPR) disease by determining level of serum adiponectin whose relation is shown between inflamation and oxidation in the present studies. Materials and Methods 32 patients with LPR ( mean age is 29.72 ± 7.06)) and 25 healthy volunteers (mean age 28 ± which is 7.86) were included in our study. The blood serum adiponectin levels, biochemical values and obesity parameters, systolic and diastolic blood pressures were measured and compared within two groups. Results and Analysis The BMI, WHR, systolic and diastolic blood pressure values and blood serum glucose, HbA1c, blood urea nitrogen, creatinin and triglyserides values were higher in LPR patients ( p< 0,05). The serum adiponectin and high-density cholestrole values noted lower in LPR patient group than healty volunterees ( p< 0,05). Discussion LPR disease can be one of the diseases that is related to lower plasma adiponectin levels. Many diseases that create cardiovascular and metabolic problems, which adiponectin levels are shown to be low , should be researched in LPR patients whom values of reflux symptom index and reflux finding score are high.

Effects of the Autologous Platelet-Rich Plasma in Nasal Pack on Postoperative Quality of Life.

Aim: The authors aimed to research the effects of autologous platelet-rich plasma, which is known for the positive effects on wound healing, on postoperatif living quality of the patients after using on nasal surgery. Methods: Patients who undergo nasal operation according to randomized patients choice have been injected with saline merocel pack and platelet-rich plasma (PRP) in their nasal path. Postoperative is followed by 1 month; Nose Obstruction Symptom Evaluation (NOSE) scala score, bleeding, pain, and crust rate have been compared between 2 groups. Results: As a result of the 1 month follow-up, it was seen that the treatment group experienced better results in terms of NOSE scale than the control group patients and this was significant difference in terms of NOSE. Less bleeding and crust was seen on the treatment group patients than the control group patients and statically significant difference was found. In terms of visual analogue scale score no statically significant difference was found between 2 groups. Conclusion: According to the authors’ study on PRP, the authors found out that by using PRP wound can be healed faster in early period of postoperative. It was seen with the authors’ research that on postoperative early period crusts, bleeding and postoperative complaints are lesser.

Plasma Glycated Albumin Levels Clearly Detect Hearing Loss and Atherosclerosis in Patients with Impaired Fasting Glucose.

Objective: To describe the relationship between atherosclerosis and hearing thresholds in prediabetic patients with impaired fasting glucose (IFG) and to determine the efficacy of glycated albumin in predicting carotid artery atherosclerosis in patients with isolated IFG. Subjects and Methods: The study included 82 patients (aged 53.73-80 years) divided into two groups based on fasting glucose levels, the IFG group: 59 patients (32 females, 54.2%), and the normal fasting plasma glucose level group: 23 patients (12 females, 52.2%). Patients underwent audiological testing to determine hearing thresholds, and carotid intima-media thickness (CIMT) was measured using carotid artery Doppler sonography. Multivariate analyses were performed to determine whether or not the plasma glycated albumin levels could predict hearing loss and CIMT. Results: Patients in the IFG group (mean age: 59.8 ± 9.5 years) had higher hearing thresholds and pure-tone average scores (PTA) than those in the group with normal glucose levels (mean age: 56.2 ± 10.1 years) (left ear: 27.65 ± 8.85 vs. 25.75 ± 21.96 dB, p = 0.021; right ear: 29.22 ± 8.51 vs. 22.39 ± 6.99 dB, p = 0.001). The CIMT was significantly higher in the IFG group than the control group (0.75 ± 0.26 vs. 0.56 ± 0.16 mm, p < 0.001 for the left and 0.74 ± 0.26 vs. 0.51 ± 0.19 mm, p < 0.001 for the right carotid arteries). Glycated albumin levels were independently related with increased CIMT (left CIMT: r = 0.32, p = 0.003; right CIMT: r = 0.42, p < 0.001), and serum glycated albumin levels were significantly associated with PTA (left ear: r = 0.28, p = 0.01; right ear: r = 0.30, p = 0.006). Conclusion: Sensorineural hearing loss was more common in patients with IFG. Plasma glycated albumin levels were strongly correlated with CIMT and carotid plaques as a marker of atherosclerosis and with hearing impairment thought to develop due to atherosclerosis in patients with IFG.

Non-invasive detection and monitoring of experimental hydrocephalus with distortion product otoacoustic emissions

OBJECTIVE We aimed to find out the effects of short term and long term hydrocephalus and intracranial ventricular volume changes on cochlear functions by using distortion product otoacoustic emission (DPOAE) in experimental hydrocephalus rat models for the first time in literature. METHODS This study was performed with 48 healthy, adult (8 weeks old), Sprague-Dawley rats which weighed between 200 and 240g. Six groups were formed in this study: short term control, short term sham, short term hydrocephalus, long term control, long term sham and long term hydrocephalus groups. Each group contained eight rats. Short term period was 4 weeks and long term period was 8 weeks after the study started. At the end of these periods, DPOAE measurements were performed and then rats were sacrificed to determine ventricular volumes. RESULTS DPOAE values at all frequencies were significantly decreased in the short term hydrocephalus group when compared to the short term control and short term sham groups. DPOAE values at all frequencies were significantly decreased in the long term hydrocephalus group when compared to the long term control and long term sham groups. Besides, long term sham group which had higher ventricular volumes than long term control group also had lower DPOAE measurements. Significant associations were present between DPOAE measurements and ventricular volumes in hydrocephalus models. CONCLUSION The functional disturbances in cochlear functions due to hydrocephalus have been demonstrated with DPOAE measurements in this study. DPOAE measurements may be thought as an easily applicable non-invasive method in detection and follow-up of patients with hydrocephalus. Our findings should be supported with clinical studies in humans.

Temporal Bone Posterior Wall Defect, a New Clinic Entity?

OBJECTIVE To define clinical and audiological findings in patients with temporal bone posterior wall defects (TBPWD) and to investigate possible relationships between these findings and the characteristics of the defect. MATERIALS AND METHODS The computed tomography (CT) views of 1198 patients with vestibulocochlear symptoms between 2007 and 2012 were retrospectively evaluated, and TBPWD and associated anomalies were investigated. Patients who had TBPWD were called back, and clinical and audiological examinations (tympanometry, pure tone audiometry, acoustic reflexes, and otoacoustic emission) were performed. RESULTS Twenty-eight (2.34%) patients had TBPWD. Twenty-three of them were eligible for the study. Size of the defect was significantly correlated with the presence of tinnitus and/or vertigo (p<0.005). The cut-off values for the largest size of TBPWD were 1.65 mm [sensitivity: 0.67 and specificity: 0.77 (95% CI: 0.58-0.97); p=0.04] in case of the presence of tinnitus and 1.85 for vertigo (sensitivity: 0.78 and specificity: 0.86 (95% CI: 0.67-0.99); p=0.006). In pure tone audiometry tests, mixed-type hearing loss was present in four (17%) patients, sensorineural hearing loss was present in three (13%) patients, and conductive-type hearing loss was present only in one (4%) patient. Otoacoustic emission tests revealed significant differences in signal/noise ratios at frequencies of 500, 750, 1000, and 6000 Hz. CONCLUSION For the first time in the literature, we defined clinical and audiological findings in patients with TBPWDs. These defects seem to cause more prevalent symptoms of vertigo and tinnitus and disturb the audiological characteristics of patients.

Diagnosis and Management of Cornu Cutaneum of Nasal Vestibule: A Rare Case Report

Cornu cutaneum is a relatively uncommon projectile, irregular, hyperkeratotic nodule that can be seen in places such as scalp, forehead, eyelids, ear, nose, lips, and upper extremities which are subjectable to sunlight. Treatment is surgery with radical margins. Excisional biopsy is enough for treatment of the lesion on head and face. However, there is only little literature about cornu cutaneum on the nasal vestibule. We present an 82-year-old male patient with a necrotic, irregular shaped lesion with pedicle on the left nasal vestibule excised and diagnosed as cornu cutaneum.