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Dive into the research topics where Hans-Joachim Knoelker is active.

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Featured researches published by Hans-Joachim Knoelker.


Alzheimers & Dementia | 2015

Standardization of a method for diagnostic biomarker validation for neurodegenerative diseases: App assays as example

Linda J. C. van Waalwijk van Doorn; Marleen J.A. Koel-Simmelink; Ute Haußmann; Hans Klafki; Hanne Struyfs; Philipp Linning; Hans-Joachim Knoelker; Harry Twaalfhoven; H. Bea Kuiperij; Eugeen Vanmechelen; Marcel M. Verbeek; Sebastiaan Engelborghs; Jens Wiltfang; Charlotte E. Teunissen

acceptable range in 144 out of 146 runs. Average values for each reagent lot are within 10% of the training set mean values. The plot shows longitudinal performance of amyloid-b results for the 2 pools. Conclusions:Using our protocol we were able to maintain acceptable performance of Ab1-42 throughout 17 months and 4 different lots of reagents. References: LM Shaw, H. Vanderstichele, M. Knapik-Czajka, et al. Acta Neuropathol. 2011 May;121(5):597-609.


Journal of Neurochemistry | 2016

Validation of soluble APP assays as diagnostic CSF biomarkers for neurodegenerative diseases

van Doorn, van, Linda J. C. Waalwijk; Marleen J.A. Koel-Simmelink; Ute Haussmann; Hans Klafki; Hanne Struyfs; Philipp Linning; Hans-Joachim Knoelker; Harry Twaalfhoven; H. Bea Kuiperij; Sebastiaan Engelborghs; Philip Scheltens; Marcel M. Verbeek; Eugeen Vanmechelen; Jens Wiltfang; Charlotte E. Teunissen


ChemInform | 2015

Transition Metals in Organic Synthesis. Part 118. Total Synthesis of 7‐ and 8‐Oxygenated Pyrano[3,2‐a]carbazole and Pyrano[2,3‐a]carbazole Alkaloids via Boronic Acid‐Catalyzed Annulation of the Pyran Ring.

Konstanze K. Julich-Gruner; O. N. Kataeva; Arndt W. Schmidt; Hans-Joachim Knoelker


ChemInform | 2015

Transition Metals in Organic Synthesis. Part 114. Silver(I)-Catalyzed Route to Pyrroles: Synthesis of Halogenated Pseudilins as Allosteric Inhibitors for Myosin ATPase and X-Ray Crystal Structures of the Protein-Inhibitor Complexes.

Hans-Joachim Knoelker


ChemInform | 2014

Transition Metal Complexes in Organic Synthesis. Part 109. Efficient Construction of Pyrano[3,2‐a]carbazoles: Application to a Biomimetic Total Synthesis of Cyclized Monoterpenoid Pyrano[3,2‐a]carbazole Alkaloids.

Ronny Hesse; Konstanze K. Gruner; O. N. Kataeva; Arndt W. Schmidt; Hans-Joachim Knoelker


ChemInform | 2014

First Total Syntheses of Chrestifoline‐B (Ia) and (.+‐.)‐Chrestifoline‐C (Ib), and Improved Synthetic Routes to Bismurrayafoline‐A (IIa), Bismurrayafolinol (IIb) and Chrestifoline‐D (IIIc).

Carsten Boerger; Arndt W. Schmidt; Hans-Joachim Knoelker


ChemInform | 2012

Synthesis of 1,3-Dienes via Metal Complexes of Dienes

Ingmar Bauer; Hans-Joachim Knoelker


ChemInform | 2010

Transition Metal Complexes in Organic Synthesis. Part 49. Development of Novel Chiral Catalysts for the Asymmetric Catalytic Complexation of Prochiral Cyclohexa-1,3-dienes by the Tricarbonyliron Fragment - Mechanism of the Asymmetric

Hans-Joachim Knoelker; Helmut Goesmann; Daniela Herzberg; Guy Rohde


ChemInform | 2010

Transition-Metal Complexes in Organic Synthesis. Part 45. 1,4-Diaryl-1-azabuta-1,3-diene-Catalyzed Complexation of Cyclohexa-1,3-diene by the Tricarbonyliron Fragment: Development of Highly Efficient Catalysts, Optimization of Reactio

Hans-Joachim Knoelker; Elke Baum; P. Gonser; Guy Rohde; H. Roettele


ChemInform | 2010

Cycloadditions of Allylsilanes. Part 16. Stereoselective Total Synthesis of (.+-.)-Fragranol by TiCl4 Promoted [2 + 2] Cycloaddition of Allyl-tert-butyldiphenylsilane and Methyl Methacrylate.

Hans-Joachim Knoelker; Gerhard Baum; Oliver Schmitt; Guenter Wanzl

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Arndt W. Schmidt

Dresden University of Technology

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Elke Baum

Dresden University of Technology

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H. Bea Kuiperij

Radboud University Nijmegen

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Harry Twaalfhoven

VU University Medical Center

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Marcel M. Verbeek

Radboud University Nijmegen

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Daniela Herzberg

Karlsruhe Institute of Technology

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Guy Rohde

Karlsruhe Institute of Technology

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Hans Klafki

University of Duisburg-Essen

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