Harel Rosen

New frontiers in medical device technology

Microwave Balloon Angioplasty Catheter Ablation for the Treatment of Cardiac Arrhythmias The Efficacy of Transurethral Thermal Ablation in the Management of Benign Prostatic Hyperplasia Localized Heating of Deep-Seated Tissues Using Microwave Balloon Catheters Microwave Surgery Contemporary Ophthalmic Lasers Advanced Technologies in Coronary Angioplasty: Lasers and Stents Advances in Magnetic Resonance Imaging Medical Ultrasonic Imaging - State-of-the-Art and Future Thermography - Radiometric Sensing in Medicine.

The role of engineering principles in the medical utilization of electromagnetic energies: Examples

The use of RF/microwaves in medicine has increased dramatically over the last ten years. RF and microwave therapies for the treatment of cancer in humans are well documented, and are presently used in many cancer centers. RF treatments for supra ventricular arrhythmias, and more recently for the treatment of ventricular tachycardia, are currently employed by major hospitals. RF/microwaves are also used in human subjects for the treatment of benign prostatic hyperplasia (BPH). In the last few years, several otolaryngological centers have been utilizing RF to treat upper airway obstruction and to alleviate sleep apnea. Many centers also utilize RF for the treatment of gastro-esophageal disease (GERD), for pain management, and for endometrial ablation. Balloon microwave catheters for ablating solid tumors, then forming cavities in those tumors for the local delivery of therapeutic agents, are currently being investigated. New modalities are being studied, such as RF/microwave for the enhancement of drug absorption and microwave septic wound treatment, microwave imaging for the detection of breast cancer, epidemiological studies on the effects of ratspsila exposure to microwave, as well as tissue regeneration using electromagnetic fields. In addition, technology is presently being developed that allows for permanent implantation of microwave wireless sensors in humans. A permanently implantable intra-cranial pressure monitor is one such application of the latter technology. Many more areas of research are currently being investigated, a partial list of which is summarized in the introduction.

Bilirubin phototransformation in vitro using a battery-powered, solar-charged, high-intensity blue light-emitting diode phototherapy blanket

The availability of new, higher intensity Blue Light-Emitting Diodes (LEDs), as used in the development of our LED phototherapy blanket, led us to hypothesise that our blue LED phototherapy system would phototransform bilirubin more rapidly, in vitro, than the current commercially available, stateof- the-art phototherapy system. Furthermore, we theorised that increasing light intensity, beyond levels previously studied, would lead to increasing rates of bilirubin phototransformation.