Hari Sharma

Direct and Indirect Costs of Non-Vertebral Fracture Patients with Osteoporosis in the US

Background: Osteoporosis is a condition marked by low bone mineral density and the deterioration of bone tissue. One of the main clinical and economic consequences of osteoporosis is skeletal fractures.Objective: To assess the healthcare and work loss costs of US patients with non-vertebral (NV) osteoporotic fractures.Methods: Privately insured (aged 18–64 years) and Medicare (aged ≥65 years) patients with osteoporosis (ICD-9-CM code: 733.0x) were identified during 1999–2006 using two claims databases. Patients with an NV fracture (femur, pelvis, lower leg, upper arm, forearm, rib or hip) were matched randomly on age, sex, employment status and geographic region to controls with osteoporosis and no fractures. Patient characteristics and annual healthcare costs were assessed over the year following the index fracture for privately insured (n = 4764) and Medicare (n = 48 742) beneficiaries (Medicare drug costs were estimated using multivariable models). Indirect (i.e. work loss) costs were calculated for a subset of privately insured, employed patients with available disability data (n = 1148). All costs were reported in

Serum Urate and Incidence of Kidney Disease Among Veterans with Gout

US, year 2006 values.Results: In Medicare, mean incremental healthcare costs per NV fracture patient were

Clinical and Economic Benefits Associated With the Achievement of Both HbA1c and LDL Cholesterol Goals in Veterans With Type 2 Diabetes

US13 387 (

Relative and attributable diabetes risk associated with hyperuricemia in US veterans with gout

US22 466 vs

The benefits of timely intervention with zoledronic acid in patients with metastatic prostate cancer to bones: a retrospective study of the US Veterans Affairs population.

US9079; p < 0.05). The most expensive patients had index fractures of the hip, multiple sites and femur (incremental costs of

Outcomes Associated with Post-Discharge Insulin Continuity in US Patients with Type 2 Diabetes Mellitus Initiating Insulin in the Hospital

US25 519,

Outcomes associated with insulin therapy disruption after hospital discharge among patients with type 2 diabetes mellitus who had used insulin before and during hospitalization.

US20 137 and

Study of Imatinib Treatment Patterns and Outcomes Among US Veteran Patients With Philadelphia Chromosome–Positive Chronic Myeloid Leukemia

US19 403, respectively). Patients with NV non-hip (NVNH) fractures had incremental healthcare costs of

Management of Patients Using Combination Therapy With Pioglitazone and a Dipeptidyl Peptidase-4 Inhibitor: An Analysis of Initial Versus Sequential Combination Therapy

US7868 per patient (

Remittances and Growth in Latin America: A Panel Unit Root and Panel Cointegration Analysis

US16 704 vs