Harold E. Stadler

Prenatal fibroelastosis (“fetal endocarditis”) manifested clinically by total heart block

Summary A case of endocardial fibroelastosis is presented which was manifested by bradycardia. The absence of maternal illness as well as absence of systemic illness on the part of the infant do not militate against a diagnosis of “fetal endocarditis” as shown by pathologic sections here. The theory of Weinberg and Himelfarb is a reasonable explanation for the cause of the death of the infant.

Discordant monozygotic twins: Disparity in the cardiac status

Summary Another instance of discordant monozygotic twins is here presented. The cardiac lesion had not up to the time of report exerted a detrimental effect upon the development of the affected member of the pair.

Hereditary ectodermal dysplasia of the anhydrotic type

Summary A report is made of two children who have hereditary ectodermaldysplasia of the anhydrotic type and of a third child who shows only anodontia and alopecia of this syndrome. The three children are closely related. The two children with the complete syndrome are first cousins; the child with the partial syndrome is a sister of one of the two children with the complete syndrome. Siblings of the two mothers are affected; however, the two mothers are normal. It is probable that the disease was transmitted through a maternal carrier state.

Ectromelia and associated development defects

Summary There is presented an infant who showed diffuse developmental defects involving the upper extremities and head. It is not possible to cstablish definitely either a hereditary or infectional basis for the skeletal changes present. Evidence that amniotic bands were responsible for “intrauterine amputation” in this case is entirely lacking.