Harry Greengard

A confirmation of the presence of pancreozymin in the duodenal mucosa.

Confirmatory evidence has been secured for the existence of pancreozymin, a hormone present in extracts of the duodenal mucosa the effect of which is to stimulate enzyme production by the pancreas. It is separated from secretin by precipitation with aniline, and stimulates equally the formation of the three chief pancreatic enzymes; it is inactivated by incubation with serum, probably on an enzyme basis.

Assay of Secretin

Conclusions The commercial secretin preparation, Pancreotest, has been assayed on dogs and found to be half as potent as our standard material. An apparent discrepancy in the expression of units of secretin has been explained.

Colloidal Sulphur to Modify Extirpation Diabetes

Conclusion The administration of colloidal sulphur in daily doses of 250 or 500 mg. has no effect on the diabetic state of the depancreatized dog.