Hasan Çetin

Liver antioxidant stores protect the brain from electromagnetic radiation (900 and 1800 MHz)-induced oxidative stress in rats during pregnancy and the development of offspring

Abstract Objectives: The present study determined the effects of mobile phone (900 and 1800 MHz)-induced electromagnetic radiation (EMR) exposure on oxidative stress in the brain and liver as well as the element levels in growing rats from pregnancy to 6 weeks of age. Methods: Thirty-two rats and their offspring were equally divided into three different groups: the control, 900 MHz, and 1800 MHz groups. The 900 MHz and 1800 MHz groups were exposed to EMR for 60 min/d during pregnancy and neonatal development. At the 4th, 5th, and 6th weeks of the experiment, brain samples were obtained. Results: Brain and liver glutathione peroxidase activities, as well as liver vitamin A and β-carotene concentrations decreased in the EMR groups, although brain iron, vitamin A, and β-carotene concentrations increased in the EMR groups. In the 6th week, selenium concentrations in the brain decreased in the EMR groups. There were no statistically significant differences in glutathione, vitamin E, chromium, copper, magnesium, manganese, and zinc concentrations between the three groups. Conclusion: EMR-induced oxidative stress in the brain and liver was reduced during the development of offspring. Mobile phone-induced EMR could be considered as a cause of oxidative brain and liver injury in growing rats.

Yenidoğan Döneminde Septik Artirit: Olgu Sunumu

SuleymanDemirel Universitesi TIP FAKULTESI DERGISI: 2006 Mart; 13(1) Yenidogan Doneminde Septik Artirit: Olgu Sunumu Aysen Turedi, Nihal Olgac Dundar, Hasan Cetin, Remzi A. Ozerdemoglu, Bumin Dundar Ozet Yenidogan septik artiriti nadir gorulur fakat ciddi bir durumdur. Genellikle hastane kaynakli enfeksiyonlarla iliskilidir ve eklemlerin sik muayenesi ile erken teshis, acil tedavi ve hastane kaynakli enfeksiyonlarin kontrolu hastaligin tedavisi icin onemlidir. Burada yuksek ates nedeniyle birden fazla merkezde tedavi gormus ve invaziv girisimlere maruz kalmasi neticesinde hastane kaynakli enfeksiyon gelisen 24 gunluk bir olgunun tedavisi sirasinda ortaya cikan sorunlarin tartisilmasi amaclanmistir. Hasta klinigimizde tedavi edilmeden once diger tedavi kurumlarinda verilen tedavi protokollerini tamamlamamisti. Sol dizden alinan kulturde hastane kaynakli bir enfeksiyonu dusunduren klebsiella uremesi nedeniyle hastaya drenaj, antibiyoterapi ve rehabilitasyon uygulanmis ve iyi netice alinmistir. Anahtar kelimeler: Septik artirit, yenidogan, invaziv girisim, hastane kaynakli enfeksiyon. Abstract Septic Arthritis in Newborn Period: A Case Report Neonatal septic arthritis is uncommon but a serious condition. It is usually related to nosocomial infection and early diagnosis by frequent examination of the joints, prompt treatment and control of nosocomial infection are important for the management. The goal of this case report is to discuss the error and difficulties during the course of treatment of a 24 days old newborn who was treated at different medical centers due to fever, and developed a nosocomial infection, possibly due to invasive procedures performed during his admittance. The patient did not complete any of the treatment protocols given at outside hospital before he was treated at our clinic. Cultures of left knee were positive for klebsiella that indicated a nosocomial infection. A good result was obtained with drainage, antibiotherapy, and rehabilitation. Key words: Septic arthritis, newborn, invasive procedure, nosocomial infection.

Yenidoğanlarda Fasiyal Antropometrik Değerler

Yuz birbiri ile entegre olarak gelisen bircok yapidan orjin aldigindan embriyolojik gelisimi komplekstir Dismorfogeneziste bircok sendromda yuzun etkilenmesi surpriz degildir Calismamizda saglikli yenidogan cocuklarda kranyofasiyal morfometrik degerlerin arastirilmasi amaclandi Kranyofasiyal anomalisi olmayan yenidogan muayenesinde normal olarak degerlendirilen herhangi bir patolojiye rastlanmayan dogum travmasi gecinmemis toplam 200 100 erkek 100 kiz olgudan yararlanildi Olgularda kafa goz burun agiz cene ve kulak bolgelerinde toplam 22 morfometrik deger arastirildi Cinsler arasinda kulak genisligi tragus cene uzunlugu kafa uzunlugu ve yuz genisligi degerleri arasinda kizlarda daha yuksek olmak uzere istatistiki acidan anlamli derecede farkliliklar oldugu p lt;0 001 tespit edildi Sonuc olarak; yenidogan muayenesinde fasiyal dismorfogenezis degerlendirilmeleri icin calismamizdaki bilgilerin faydali olacagi kanaatindeyiz Anahtar kelimeler: Kranyofasiyal Morfometri Yenidogan Kranyofasiyal Gelisim

Ön Fontanel Boyutları ve Kapanma Zamanı

Bu calisma Isparta yoresindeki saglikli cocuklarda normal fontanel boyutlarini ve kapanma zamanlarini saptamak amaciyla yapildi Calisma kapsamina alinan ve yaslari bes gun ile 20 ay arasinda degisen 1252 cocugun 611 kiz 641 erkek on fontanel boyutlari bas cevresi vucut agirligi ve boy olcum degerleri belirlendi Yenidogan doneminde on fontanel capinin ortalama degeri 31 5±1 mm altinci ayda 19±1 mm bulundu On fontanelin kapanma orani 12 aylik cocuklarda 42 5 16 aylik cocuklarda 85 18 aylik cocuklarda ise 90 8 olarak bulundu Fontanel boyutlari ve kapanma zamanlari bakimindan her iki cins arasinda istatistiksel olarak anlamli fark yoktu Anahtar kelimeler: Anterior Fontanelle Size And Closure Time

Kal a-Azarlı Bir Çocuk Vakası

SuleymanDemirel Universitesi TIP FAKULTESI DERGISI: 1999 Aralik; 6(4) Kal a-Azarli Bir Cocuk Vakasi Bahattin Tunc, Hasan Cetin, Habibe Gur Ozen Ozet Iki yasindaki erkek hasta anemi, trombositopeni, abdominal distansiyon ve ates sikayetleri ile geti¬rildi. Hastanin kemik iligi aspirasyon incelemesinde amastigot formdaki leishmania protozoonlan go¬rulerek kala-azar tanisi konuldu. Anahtar Kelimeler: Cocuk, leishmania, kala-azar Abstract Kala-Azar In a Child A two-years-old boy was admitted to our hospital with anemia, thrombocytopenia, abdominal distention and fever. The diagnosis of kala-azar was confirmed by demonstrating markedly increase of amastigote form of Leishmania donovani in the bone marrow aspiration sample. Key Words: Child, leishmania, kala-azar

Normal Spontan Yolla veya Sezaryenle Doğan Yenidoğanlarda Kranyofasiyal Morfometrik Boyutların Karşılaştırılması

SuleymanDemirel Universitesi TIP FAKULTESI DERGISI: 1999 Mart; 6(1) Normal Spontan Yolla veya Sezaryenle Dogan Yenidoganlarda Kranyofasiyal Morfometrik Boyutlarin Karsilastirilmasi M. Ali Malas, Hasan Cetin, Hakan Kaya, Ahmet Salbacak, Alper Aler, Osman Sulak Ozet Amac: Bu calismada sezaryen ile dogan yenidoganlar ile normal spontan yolla dogan yenidoganlardaki kranyofasiyal morfometrik degerleri arasinda farkliliklarin olup olmadigi arastirildi. Gerec ve yontem: Kranyofasiyal anomalisi olmayan, muayenesi normal degerlendirilen, dogum travmasi gecirmemis toplam 166 (92 erkek, 74 kiz) yenidogan calismaya dahil edildi. Tum bebeklerde kranyofasiyal bolgeden toplani 10 antropometrik deger arastirildi. Bulgular: Normal spontan yolla dogan yeni doganlarda cinsler arasinda tragus-cene ve yuz yuksekligi anlamli olarak farkliydi (p<0.05). Sezaryenle dogan bebeklerde cinsler arasinda tragus-cene ve yuz genisliginde istatistiksel acidan anlamli farklilik tespit edildi. Normal spontan yol ve sezaryenle dogan yenidoganlardan erkeklerde; kafa uzunlugu, intermaksiller mesafe ve alt yuz yuksekligi boyutlari ile dogum kilosu arasinda; sezaryenle dogan bebeklerde daha fazla olmak uzere anlamli farkliliklar tespit edildi. Kizlarda ise kafa uzunlugu, kafa genisligi, yuz yuksekligi, yuz genisligi, intermaksiller mesafe, ust yuz yuksekligi, alt yuz yuksekligi ve dogum kilosu arasinda anlamli farkliliklar tespit edildi. Sonuc: Normal spontan yolla veya sezaryenle dogan yenidoganlann muayenesinde kafa ve yuz gelisiminin degerlendirilmesi icin yeni veriler elde edildi. Anahtar Kelimeler: Kranyofasiyal antropometri, yenidogan, sezaryen Abstract Comparison of Craniofacial Morphometric Measurements Between Babies Who Have Born by Cesarean Section or by Spontaneous Delivery Aim of this study is to determine \vhether craniofacial morphometric measurements \vere different between babies \vho have been delivered by cesarean section or by spontaneous delivery. One hundred and sixty-six babies (92 males and 74 females) who have no congenital anomalies, no birth trauma and no pathology had been found at their fist physical examination were included in the study. Over ali 10 anthropometric values were examined. Tragus-jaw diameter andface lengths were found significantly different between male andfemale babies in spontaneous delivery group. in the cesarean section group, tragus-jaw diameter andface \vidths \vere found significantly different between different sexes. it was found out that males who have been delivered by cesarean section had significantly higher cranial length, inter maxillary diameter, lowerface length and birth tveight in comparison vvith the others of the same gender. As for females, the significantly different properties turned out to be cranial length, cranial width, face length, face \ridth, intermaxillary diameter, upper face length, lower face length and birth \veight. New data was obtainedfor evaluation ofhead andface development in neonates who have been delivered by cesarean section or by spontaneous delivery. Key Words: Craniofacial antropometry, nevvborn, cesarean section

Çocukluk Çağında Hematüri ve Tanısal Yaklaşım

SuleymanDemirel Universitesi TIP FAKULTESI DERGISI: 1996 Mart; 3(1) Cocukluk Caginda Hematuri ve Tanisal Yaklasim Ali Ayata Faruk Oktem Hasan Cetin Ahmet R. Ormeci Gulderen Ozeren Ozet Makroskopik (gros) veya mikroskopik olabilen hematittiler glonieruler veya ekstraglomeruler bozukluklara bagli gelisebilir ve bir idrar tetkikiyle orijinin saptanmasi genellikle mumkundur. Ilk olarak stikle saptanilan hematurilerin, ayrica dikkatli bir mikroskopik muayeneyle dogrulanmasi gerekir. Yenidoganlarda hematim oncelikle hipoksi, tromboz, dolasim bozuklugu gibi vaskuler kaynakli olurken daha buyuk cocuklarda hayta uriner enfeksiyonlar olmak uzere glomerulonefritler ve travmalara bagli olarak gelismektedir. Hiperkalsiuri ve nefroUtiyazis de hematuriye neden olabilir. Anahtar Kelimeler: Hematuri, tantsalyaklasim. Abstract Diagnostic Approach for Heniaturia in Childhood Heniaturia may be grosa or microscopic. it can resiilt from glomerular or extraglomerular pathology, which can often be clinically distitiguished by urinalysis. Initial detection of hematuria, usually by dipstick but at times by the appearance ofthe itrine, should be followed by confirmation with careful microscopic aiuilysis. Hematuria in newborns results primarlyfrom vascular disorders such as hypoxia, thrombosis, or circulatory compromise; in older children, urinary tract infections accountfor the majority of cases, follovved by glomeritlonephritis and trauma. Hypercalciuria and nephroUthiasis also can cause hematuria. Key Words: Hematuria, diagnostic approach.

Bakteriyel Menenjitli Çocuklarda Deksametazon Tedavisi

SuleymanDemirel Universitesi TIP FAKULTESI DERGISI: 1996 Haziran; 3(2) Bakteriyel Menenjitli Cocuklarda Deksametazon Tedavisi Faruk Oktem Ali Ayata Hasan Cetin Ahmet Rifat Ormeci Ozet Bakteriyel menenjiti! cocuklarda deksametazon kullaniminin, meningeal inflamasyonu onleyerek odiyolojik ve norolojik sekelleri azalttigi gosterilmistir. Bu tedavinin avantajlari, ozellikle ilk antibiyotik dozundan once verilirse, dezavantajlarindan daha fazladir. Anahtar Kelimeler: Bakteriyel menenjit, deksametazon tedavisi Abstract Dexamethasone Therapy for Children with Bacterial Meningitis Dexamethasone therapy in children vvith bacterial meningitis is recorded to reduce hearing loss and other neurologic seguelae by preventing meningeal inflammation. The advantages of dexamethasone treatment, especially when given before the first parenterally administered antibiotic dose, clearly outweigh thepossible dis advantages. Key Words: Bacterial meningitis, dexamethasone therapy