Network


Latest external collaboration on country level. Dive into details by clicking on the dots.

Hotspot


Dive into the research topics where Hasan Tahsin Gozdas is active.

Publication


Featured researches published by Hasan Tahsin Gozdas.


The Eurasian Journal of Medicine | 2015

Factors Affecting Hand Hygiene Adherence at a Private Hospital in Turkey

Bahri Teker; Aziz Ogutlu; Hasan Tahsin Gozdas; Saliha Ruayercan; Gulizar Hacialioglu; Oguz Karabay

OBJECTIVE Nosocomial infections are the main problems rising morbidity and mortality in health care settings. Hand hygiene is the most effective method for preventing these infections. In this study, we aimed to investigate the factors related with hand hygiene adherence at a private hospital in Turkey. MATERIALS AND METHODS This study was conducted between March and June 2010 at a private hospital in Turkey. During the observation period, employees were informed about training, then posters and images were hanged in specific places of the hospital. After the initial observation, training on nosocomial infections and hand hygiene was provided to the hospital staff in March 2010. Contacts were classified according to occupational groups and whether invasive or not. These observations were evaluated in terms of compatibility with hand hygiene guidelines. RESULTS Hand hygiene adherence rate of trained doctors was higher than untrained ones before patient contact and after environment contact [48% (35/73) versus 82% (92/113) p<0.05 and 23% (5/22) versus 76% (37/49) p<0.05 respectively]. Hand hygiene adherence rate of trained nurses was higher than untrained ones before patient contact [63% (50/79) versus 76% (37/49) p<0.05]. Hand hygiene adherence rate of trained assistant health personnel was higher than untrained ones before asepsis [20% (2/10) versus 73% (16/22) p<0.05]. In addition, it was seen that hand antiseptics were used when hand washing was not possible. CONCLUSION The increase at the rate of hand washing after training reveals the importance of feedback of the observations, as well as the training. One of the most important ways of preventing nosocomial infections is hand hygiene training that should be continued with feedbacks.


American Journal of Emergency Medicine | 2015

The importance of rabies immunoglobulin in postexposure prophylaxis

Hasan Tahsin Gozdas

also at postoperative analgesia. Major complications including rib fractures, pneumothorax, esophageal injuries, and bleeding may occur in the thoracic trauma cases admitted to the emergency department [2-4]. Even if isolated rib fractures or fractures may not be early mortal, it may be mortal lately because of secondary pneumonia due to pain [5]. Treatment methods for pain are mainly NSAIDs, opioid analgesics, thoracic epidural analgesia, and PVB. Paravertebral block is an effective method in rib fractures, but PVB is providing only ipsilateral segmental thoracic analgesia [6]. Finally, we think that retrolaminar block is a very useful technique for pain relief with safety for other techniques. But PVB is effective at the block side and segmental. For this reason, it is not very practical at multilocation pain like multiple rib fractures.


Human Vaccines & Immunotherapeutics | 2014

Safety of purified chick embryo cell rabies vaccine (Vaxirab N) after pre-exposure prophylaxis against rabies in children: is only adverse event profile enough?

Hasan Tahsin Gozdas; Oguz Karabay

Dear Sir, We read the article recently published in your journal entitled “Pre-exposure prophylaxis against rabies in children: Safety of purified chick embryo cell rabies vaccine (Vaxirab N) when administered by intradermal route” by Ravish et al.1 with great interest. Rabies is still a significant cause of morbidity and mortality in developing countries.2 CDC and WHO strongly recommend pre-exposure prophylaxis (PrEP) for high risk individuals living in endemic areas.3,4 The authors assumed that purified chick embryo cell (PCEC) vaccine is safe when administered by intradermal route for PrEP against rabies in children. However, certain points should be clarified. First, therapeutic index is a measure of drug or vaccine safety. Therefore, safety should be determined when a drug or vaccine was known to reach clinically desired or effective dose.5 However, the authors claimed that their study is the first to demonstrate the safety of PCEC vaccine when administered by intradermal route for PrEP against rabies in children. Such method is a questionable approach in terms of scientific base. To our knowledge, safety of pre-exposure intradermal PCEC rabies vaccine has not been determined yet. We don’t know whether intradermal PCEC rabies vaccine is effective or not. So, firstly efficacy then safety should be tested. Second, efficacy of rabies vaccine in PrEP can be determined by studying rabies neutralizing antibodies in sera of vaccinated humans. While an antibody response of 0.5 IU/ml and above shows protectivity against rabies, values below 0.5 IU/ml can be interpreted as the absence of protective response or vaccine efficacy.4 Although various components of immune system are effective in vaccine response, survival after infection is mainly provided by rabies neutralizing antibodies. Studying rabies antibodies in serum is therefore essential for the detection of occurring immunity.6 So, vaccine efficacy could be demonstrated by studying rabies antibodies in sera of vaccinated children. Lastly, the authors found PCEC vaccine to be safe for PrEP against rabies in children by considering only adverse event profile. However, it should be shown that vaccine had reached protective and effective level in serum. In conclusion, it could be more pertinent to decide on the safety of intradermal PCEC rabies vaccine if the authors investigated antibody response to vaccine before investigating adverse event profile.


Indian Journal of Pharmacology | 2015

Reversible bilateral ototoxicity in a patient with chronic hepatitis B during peginterferon alpha-2a treatment

Hasan Tahsin Gozdas; Oguz Karabay

Peginterferon alpha-2a (PEG IFN α-2a) is frequently used in chronic hepatitis B (CHB)treatment. Numerous adverse events can be noted during this therapy such as flu-like disease, rash, weight loss and depression. However, PEG IFN α-2a related ototoxicity seems to be an uncommon entity. Ototoxicity can be detected objectively by audiometry. In this paper, we present a case of CHB who developed reversible bilateral ototoxicity during PEG IFN α-2a treatment. Due to ototoxicity detected objectively by audiogram, treatment was ceased at sixth month and ototoxicity completely recovered one month after stopping the drug.


Indian Journal of Medical Research | 2015

The role of procalcitonin in febrile patients.

Mustafa Hatipoglu; Hasan Tahsin Gozdas

Sir, We read the article by Qu et al1 with great interest. The authors investigated the role of procalcitonin (PCT) in distinguishing bacterial infections in febrile patients. We believe that this topic can be enriched with the points listed below: Groups 1 and 2 represented bacterial infection groups which consisted of 161 hospital acquired infection cases (58%) and 115 community acquired infection cases (42%). If there are significant differences in the levels of PCT, C-reactive protein (CRP), interleukin-6 (IL-6) and serum amyloid A (SAA) between hospital acquired infection and community acquired infection cases, it can be useful in guiding antibiotic treatment. Bacterial pneumonia was the most common diagnosis in their study, but Streptococcus pneumoniae which is the most common aetiological agent of pneumonia, was not isolated in any of their febrile patients. This point should be clarified. The PCT level of some patients in the bacterial infection group was below the cut-off level. It is important to know which infections and bacteria cause low PCT levels. Mortality among patients was not mentioned. It would be important to know whether there was a significant difference in PCT levels between survivors and non-survivors. Finally, we think that the aforementioned data will be helpful to increase the significance of PCT especially in emergency department and intensive care unit.


Indian Journal of Medical Research | 2015

Age, gender & co-morbidities as risk factors for drug-induced diseases.

Hasan Tahsin Gozdas; Dilek Arpaci

Sir, The study by Tandon and colleagues1 on drug-induced diseases (DIDs) is very interesting. However, we have some comments regarding this study. An important portion of the study population was geriatric patients (54%). Also, the number of females was significantly more than males (1.7 vs 1). As stated by Zopf et al2, advanced age and female gender were important risk factors for DIDs. So, these two factors might have significantly affected the results of this study. As seen in Table I, there was a significant difference between the number of patients with single disease and co-morbid conditions (P<0.001). It would be important to know how many patient in this study had diabetes mellitus, chronic renal insufficiency, hepatic insufficiency or AIDS. Because, such co-morbidities cause secondary immune deficiencies and patients having these co-morbidities are more susceptible to adverse effects of immunosuppressive medications such as methotrexate, cyclophosphamide and corticosteroids3.


Indian Journal of Medical Research | 2015

Antibody response to hepatitis B vaccination in isolated anti-HBc positive subjects

Hasan Tahsin Gozdas

Sir, I read with interest the article by Sugunan et al1 on impact of hepatitis B immunization among the Nicobarese tribe. The authors investigated protective antibody response after hepatitis B vaccination in their study. I feel that several points in this study need to be clarified. Hepatitis B infection has been reported to be hyperendemic in Nicobarese where this study was conducted. As per the inclusion criteria, subjects negative for both HBsAg and Anti-HBs were included in the study. However, hepatitis B core antibody (anti-HBc) status of the study population was not mentioned. This condition could be a confounding factor. Because hepatitis B vaccine is not recommended for isolated anti-HBc positive subjects (HBsAg and anti-HBs negative) living in highy endemic areas due to the high probability of previous exposure to hepatitis B infection2. Isolated anti-HBc positivity might be present in these subjects who were at high risk for prior exposure to hepatitis B infection. Antibody response after hepatitis B vaccination may be different in isolated anti-Hbc positive subjects from that of naive subjects3. In addition, primary anti-HBs response develops when anti-HBc was positive at a low titre; whereas secondary or anamnestic antibody response develops when anti-HBc was positive at a high titre3,4. Subjects enrolled in this study might be heterogeneous in terms of anti-Hbc status due to sampling error. Further in this study1, protective antibody level was tested one month after each vaccine dose and after the completion of vaccine series at second, third and fifth year. As understood from the Figure, protective antibody level after the third vaccine dose was tested at sixth month rather than the seventh month. However, as mentioned in the article, protective levels should have been checked one month after each vaccine dose (after the third dose of vaccine at seventh month not at sixth month). I think there is a typographical error in the figure.


Turkish Nephrology Dialysis Transplantation | 2014

Uterine Prolapse as a Cause of Chronic Renal Failure

Savas Sipahi; Ozkan Gungor; Serdar Olt; Fatma Keskin; Emine Ulku Yilmaz; Hasan Tahsin Gozdas

Uterine prolapse, common in old and multiparous women, has been reported as a rare cause of obstructive uropathy. In this case, the management of a 75-year-old female patient who presented at the outpatient clinic with a history of anuresis and diagnosed with total uterine prolapse, bilateral hydronephrosis, urinary infection and acute renal failure is presented. The renal failure clinical picture regressed with appropriate treatment. However, the patient refused surgery and chose to have a pessary implemented. Four months after dismissal, she was readmitted to the hospital with recurrent renal failure that required dialysis treatment. The patient did not respond to therapy and was placed on a chronic dialysis program with a diagnosis of end-stage renal disease due to posterenal causes.


American Journal of Infection Control | 2014

Immune response to diphtheria booster vaccination.

Hasan Tahsin Gozdas; Oguz Karabay

We read the recently published article byWiboonchutikul et al1 with great interest. The authors investigated diphtheria immunity in health care workers at enrollment and after diphtheria tetanus toxoid booster vaccinations. However, we think that some points in this study should be clarified. Although the first booster was administered to all participants after baseline blood collection, the second booster was administered 6 weeks thereafter to the participants who demonstrated no seroprotection. Serum samples for investigating baseline immunity had been obtained prior to the first booster; however, it is not clear when the serum samples were obtained after booster vaccinations. It is well known that vaccine antibody response changes depending on the postvaccination sampling time. In accordance with this knowledge, serum collection time after booster vaccination was clearly described in previous studies regarding diphtheria immunity.2,3 Therefore, we think that the results of this study would be more accurate if the authors explained when they obtained the serum samples after the booster vaccinations. In addition, the rate of baseline nonimmune subjects is quite low (10%). If this rate was higher, their data would be more powerful and meaningful. Also, the effect of agemight be evaluated more accurately if older adults also participated.


American Journal of Emergency Medicine | 2014

Protective effect of tetanus antibodies

Hasan Tahsin Gozdas; Oguz Karabay

lead to miss the diagnosis of PNX. A double lung point can be detected in PNX secondary to trauma when pulmonary contusions can cause pleural adhesion or, less frequently, even in spontaneous PNX of young adults.” Volpicelli 2013 Sonographic signs of complex pneumothorax “Double lung point: when for some reason, the air of a pneumothorax is not free to float inside the pleural space, a minimal amount of pleural air may remain in the lateral or dorsal chest without migrating in the most superior area in a supine patient, which corresponds to the anterior-inferior chest zone. In this case, the operator may visualize two lung points, ie, the alternating patterns of sliding and non-sliding lung intermittently appearing at the two opposite sides of the scan. These two lung points represent the visualization of the two edges of the air trapped in the pleural space. Pneumothorax with air trapping may be caused not only by pleural adherences in chronic pleural and pulmonary diseases but also by acute lung contusions in blunt torso trauma. Even without abnormal pleural adherences, very small spontaneous pneumothoraces may not have enough pressure to allow complete detachment of the pleural layers and the floating of air towards the most superior chest areas. Being aware of this condition or in case of strong suspicion, the operator should always complete the scan of the lateral chest in the supine patient to confirm lung siding even when this latter is first visualized in the parasternal anterior-inferior chest. In the unstable patient, this extension of the technique is less important. Presence of lung sliding in the anterior-inferior chest may conclude the ultrasound examination, unless the patient is intubated for pressure ventilation or is going to be transported by helicopter. In these two latter cases, the lateral chest should always be scanned to rule out even the smallest pneumothorax that may need to be monitored or warrant prophylactic drainage.”

Collaboration


Dive into the Hasan Tahsin Gozdas's collaboration.

Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar

Ali Tamer

Abant Izzet Baysal University

View shared research outputs
Top Co-Authors

Avatar
Top Co-Authors

Avatar
Top Co-Authors

Avatar

Dilek Arpaci

Zonguldak Karaelmas University

View shared research outputs
Top Co-Authors

Avatar
Top Co-Authors

Avatar

Esra Kocoglu

Abant Izzet Baysal University

View shared research outputs
Researchain Logo
Decentralizing Knowledge