Hedvig Balázs

Association between Novelty Seeking of opiate-dependent patients and the catechol-O-methyltransferase Val158Met polymorphism

BACKGROUND Candidate genes of the dopaminergic system have been reported as key elements in shaping human temperament. Catechol-O-methyltransferase (COMT) plays a vital role in dopamine inactivation, and the Val(158)Met single nucleotide polymorphism (rs4680) in its gene has been recently associated with the Novelty Seeking (NS) temperament scale of the Temperament and Character Inventory in studies of healthy adults, as well as methamphetamine abusers. METHOD Our goal was to examine the association between temperament dimensions of the Temperament and Character Inventory and the COMT Val(158)Met variation in a Hungarian sample of 117 heroin-dependent patients and 124 nondependent controls. RESULTS Case-control analysis did not show any significant difference in allele or genotype distributions. However, dimensional approach revealed an association between the COMT Val(158)Met and NS (P = .01): both controls and opiate users with Met/Met genotypes showed higher NS scores compared to those with the Val allele. The NS scores are also significantly higher among opiate users; however, no interaction was found between group status and COMT genotype. CONCLUSION Association of the COMT polymorphism and NS temperament scale has been shown for heroin-dependent patients and controls regardless of group status.

Confirmation of the three-factor model of the Assessing Emotions Scale (AES): Verification of the theoretical starting point

Several measures have been developed for the quantification of emotional intelligence. One widely applied method is the Assessing Emotions Scale, whose factor structure has attracted much scientific attention. The objective of the present study was to identify which of the previously suggested models are the most appropriate. By applying confirmatory factor analysis, we have tested the original one-, three-, four-, and six-factor solutions. Results confirmed the three-factor structure to be the most suitable solution. We suggest that the factors in this structure are better described by the labels “appraisal of emotions,” “optimism and regulation of emotions,” and “intrapersonal and interpersonal utilization of emotions.” Supplemental materials for this article may be downloaded from http://brm.psychonomic-journals.org/content/supplemental.

Implicit Motive Profile of Treatment-Seeking Opiate Users: High Affiliation and Low Achievement

Abstract Research on basic human motives (achievement, affiliation, and power) encoded at the emotional level recently returned to the forefront of scientific research. To date, there are only a few studies on the pattern of implicit motives of substance users, so the present study examined opiate users participating in methadone maintenance treatment (N = 80) along these dimensions, comparing them to 40 non-substance users. Participants were asked to create stories on the basis of the pictures of the Thematic Apperception Test. The stories were analyzed using the content analysis method of David Winter (1991). Like other substance user groups, opiate-dependent persons used less achievement and more affiliation notions in creating stories, while there was no significant difference between the two groups concerning power notions. The results proved to be independent of the presence of anxiety and depression symptoms, despite substance users reporting higher levels of these, and suggest that motivational factors are worth considering in treatment planning.