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Dive into the research topics where Heike Gielen-Haertwig is active.

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Featured researches published by Heike Gielen-Haertwig.


Archive | 2005

(5s) -3-[(s)-fluoro (4-trifluoromethylphenyl) methyl]-5,6,7,8-tetrahydroquinoline-5-ol derivatives and use thereof as cetp inhibitors

Hilmar Bischoff; Heike Gielen-Haertwig; Volkhart Min-Jian Li; Carsten Schmeck; Michael Thutewohl; Martina Wuttke; Alexandros Vakalopoulos; Olaf Weber


Archive | 2005

Crystal structure of enzyme and uses thereof

Peter Reinemer; Heike Gielen-Haertwig; Ulrich Rosentreter; Volkhart Min-Jian Li; Axel Harrenga; Dietmar Schomburg; Karsten Niefind; Guido Hansen


Archive | 2007

Use of1,4-diaryl-dihydropyrimidine-2-on derivatives for treating pulmonary arterial hypertension

Franz von Nussbaum; Heike Gielen-Haertwig; Martina Klein; Volkhart Min-Jian Li; Daniel Meibom; Peter Sandner; Klemens Lustig; Stefan Schäfer


Archive | 2009

1-phenyl1-3,4-dihydropyrimidin-2(1H)-one derivatives and their use

Heike Gielen-Haertwig; Volkhart Min-Jian Li; Ulrich Rosentreter; Karl-Heinz Schlemmer; Swen Allerheiligen; Leila Telan; Lars Bärfacker; Jörg Keldenich; Mary F. Fitzgerald; Kevin Nash; Barbara Albrecht; Dirk Meurer


Archive | 2006

Use of 1,4-diaryl-dihydropyrimidin-2-one derivative for producing a medicament for the treatment and/or prophylaxis of e.g. pulmonary arterial hypertension, chronic-obstructive lung diseases and sleep apnea syndrome

Heike Gielen-Haertwig; Martina Klein; Volkhart Dr. Li; Klemens Lustig; Daniel Meibom; Franz Dr. Nussbaum; Peter Sandner; Stefan Schäfer


Archive | 2003

5-ethyl-imidazo (5,1-f) (1,2,4,) triazin-4 (3h) -ones as phosphodiesterase inhibitors

Cristina Alonso-Alija; Heike Gielen-Haertwig; Martin Michels; Dagmar Karthaus; Hilmar Bischoff; Nils Burkhardt; Volker Geiss; Karl-Heinz Schlemmer; Nigel Cuthbert; Mary F. Fitzgerald; Graham Sturton; Ulrich Niewöhner


Archive | 2006

New spiro-cyclohexyl-pyridine compound is cholesterol ester transfer protein inhibitor useful to treat and/or prevent coronary heart diseases, hypolipoproteinemia, dyslipidemia, hypertriglyceridemia, hyperlipidemia, restenosis and obesity

Hilmar Bischoff; Heike Gielen-Haertwig; Volkhart Dr. Li; Carsten Schmeck; Michael Thutewohl; Alexandros Vakolopoulos; Olaf Weber; Martina Wuttke


ChemMedChem | 2015

Cover Picture: Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases (ChemMedChem 7/2015)

Franz von Nussbaum; Volkhart Min-Jian Li; Swen Allerheiligen; Sonja Anlauf; Lars Bärfacker; Martin Bechem; Martina Delbeck; Mary F. Fitzgerald; Michael Gerisch; Heike Gielen-Haertwig; Helmut Haning; Dagmar Karthaus; Dieter Lang; Klemens Lustig; Daniel Meibom; Joachim Mittendorf; Ulrich Rosentreter; Martina Schäfer; Stefan Schäfer; Jens Schamberger; Leila Telan; Adrian Tersteegen


Archive | 2007

New 4-chromenonyl-1,4-dihydropyridine derivatives, useful for treatment of e.g. aldosteronism, hypertension and cardiac insufficiency, are antagonists of the mineralcorticoid receptor

Jens-Kerim Ergüden; Perez Santiago Figueroa; Ingo Flamme; Heike Gielen-Haertwig; Rolf Grosser; Heike Heckroth; Peter Kolkhof; Alexander Kuhl; Dieter Dr. Lang; Karl-Heinz Schlemmer


Archive | 2007

New 8-dihydropyridyl-chromene derivatives, useful for treatment and prevention of e.g. aldosteronism, hypertension and cardiac insufficiency, are antagonists of the mineralcorticoid receptor

Eva-Maria Becker; Jens-Kerim Ergüden; Perez Santiago Figueroa; Ingo Flamme; Heike Gielen-Haertwig; Rolf Grosser; Heike Heckroth; Peter Kolkhof; Alexander Kuhl; Karl-Heinz Schlemmer

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