Karl-Heinz Schlemmer
Bayer Corporation
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Publication
Featured researches published by Karl-Heinz Schlemmer.
BMC Pharmacology | 2007
Michael G Hahn; Cristina Alonso-Alija; Friederike Stoll; Markus Heil; Joachim Mittendorf; Karl-Heinz Schlemmer; Frank Wunder; Johannes-Peter Stasch
Soluble guanylate cyclase (sGC) is a signal-transduction enzyme activated by nitric oxide (NO) and plays a key role in a variety of physiological processes such as vasodilatation, antiaggregation, antiproliferation and neuronal signaling as well as in a variety of disorders of these functions. Current therapies that involve the use of organic nitrates and other NO donors have limitations, including non-specific interactions of NO with various biomolecules and lack of response and the development of tolerance [1,2]. Compounds that activate sGC in an NO-independent manner might therefore provide considerable therapeutic advantages.
Archive | 2007
Hartmut Schirok; Nils Griebenow; Chantal Fürstner; Joachim Mittendorf; Johannes-Peter Stasch; Frank Wunder; Karl-Heinz Schlemmer; Stefan Heitmeier; Friederike Stoll
Archive | 2002
Haertwig Heike Gielen; Volkhart Min-Jian Li; Ulrich Rosentreter; Karl-Heinz Schlemmer; Swen Allerheiligen; Kevin Nash; Mary F. Fitzgerald
Archive | 2001
Frank-Gerhard Böss; Martin Hendrix; Gerhard Konig; Karl-Heinz Schlemmer; R. Schreiber; Der Staay Franz-Josef Van; Dagmar Schauss; Ulrich Niewöhner
Archive | 2003
Martin Hendrix; David Brückner; Arno Friedl; Irene Gerlach; Volker Hinz; Jörg Keldenich; Frank Mauler; Ulrich Niewöhner; Maria Theresia Niewohner; Dagmar Karthaus; Karl-Heinz Schlemmer; Adrian Tersteeger; Ozkan Yalkinoglu
Archive | 2008
Alexander Straub; Thomas Lampe; Jens Pohlmann; Susanne Roehrig; Elisabeth Perzborn; Karl-Heinz Schlemmer
Archive | 2003
Barbara Albrecht; Michael Gerisch; Michael Härter; Thomas Krahn; Felix Oehme; Karl-Heinz Schlemmer; Henning Steinhagen
Archive | 2004
Ulrich Niewöhner; Helmut Haning; Thomas Lampe; Mazen Es-Sayed; Gunter Schmidt; Erwin Bischoff; Klaus Dembowsky; Elisabeth Perzborn; Karl-Heinz Schlemmer
Archive | 2003
Michael Härter; Jens Ergüden; Frank Wunder; Hanna Tinel; Johannes Köbberling; Eva-Maria Becker; Klaus Münter; Karl-Heinz Schlemmer; Raimund Kast; Peter Kolkhof; Gunter Karig; Lars Bärfacker; Walter Hübsch; Joachim Schuhmacher; Susanne Zuleger; Arnel Concepcion; Haruka Shimizu
Archive | 2002
Cristina Alonso-Alija; Heike Gielen; Martin Hendrix; Dagmar Schauss; Hilmar Bischoff; Nils Burkhardt; Volker Geiss; Karl-Heinz Schlemmer; Nigel Cuthbert; Mary F. Fitzgerald; Graham Sturton; Ulrich Niewöhner
