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Hironori Ohtsu

University of North Carolina at Chapel Hill

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Publication

Featured researches published by Hironori Ohtsu.

Bioorganic & Medicinal Chemistry | 2002

Antitumor agents. Part 214: synthesis and evaluation of curcumin analogues as cytotoxic agents.

Junko Ishida; Hironori Ohtsu; Yoko Tachibana; Yuka Nakanishi; Kenneth F. Bastow; Masahiro Nagai; Hui Kang Wang; Hideji Itokawa; Kuo Hsiung Lee

Fifty-eight curcumin analogues were prepared and evaluated for in vitro cytotoxicity against a panel of human tumor cell lines. Compound was the most potent analogue against several cell lines, including HOS (bone cancer) and 1A9 (breast cancer), with ED50 values of 0.97 and <0.63 microg/mL, respectively.

Journal of Medicinal Chemistry | 2002

Antitumor Agents. 217. † Curcumin Analogues as Novel Androgen Receptor Antagonists with Potential as Anti-Prostate Cancer Agents

Hironori Ohtsu; Zhiyan Xiao; Junko Ishida; Masahiro Nagai; Hui Kang Wang; Hideji Itokawa; Ching Yuan Su; Charles C.Y. Shih; Tzuying Chiang; Eugene B. Chang; Yi-Fen Lee; Meng Yin Tsai; Chawnshang Chang; Kuo Hsiung Lee

Archive | 2005

Novel curcumin analogues and uses thereof

Kuo-Hsiung Lee; Li Lin; Charles C. Y. Shih; Ching-Yuan Su; Junko Ishida; Hironori Ohtsu; Hui-Kang Wang; Hideji Itokawa; Chawnshang Chang

Bioorganic & Medicinal Chemistry | 2003

Antitumor agents 222.† Synthesis and anti-androgen activity of new diarylheptanoids

Hironori Ohtsu; Hideji Itokawa; Zhiyan Xiao; Ching Yuan Su; Charles C.Y. Shih; Tzuying Chiang; Eugene B. Chang; Yi-Fen Lee; Shang Yi Chiu; Chawnshang Chang; Kuo Hsiung Lee

Bioorganic & Medicinal Chemistry | 2003

Antitumor agents 216. Synthesis and evaluation of paclitaxel-camptothecin conjugates as novel cytotoxic agents

Hironori Ohtsu; Yuka Nakanishi; Kenneth F. Bastow; Fang Yu Lee; Kuo Hsiung Lee

Archive | 2009

***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***Curcumin analogues and uses thereof

Kuo Hsiung Lee; Li Lin; Charles C. Y. Shih; Ching-Yuan Su; Junko Ishida; Hironori Ohtsu; Hui-Kang Wang; Hideji Itokawa; Chawnshang Chang

Archive | 2005

Neue curcuminanaloge und verwendungen dafür

Kuo-Hsiung Lee; Li Lin; Charles C.Y. Shih; Ching-Yuan Su; Junko Ishida; Hironori Ohtsu; Hui-Kang Wang; Hideji Itokawa; Chawnshang Chang

Archive | 2005

Nouveaux analogues de curcumine et leurs utilisations

Chawnshang Chang; Junko Ishida; Hideji Itokawa; Kuo-Hsiung Lee; Li Lin; Hironori Ohtsu; Charles C.Y. Shih; Ching-Yuan Su; Hui-Kang Wang

Archive | 2003

Neue curcuminanaloga und deren anwendungen

Chawnshang Chang; Junko Ishida; Hideji Itokawa; Kuo Hsiung Lee; Hironori Ohtsu; Charles C. Y. Shih; Hui-Kang Wang

Archive | 2003

New curcuminanaloga and their applications

Kuo-Hsiung Lee; Junko Ishida; Hironori Ohtsu; Hui-Kang Wang; Hideji Itokawa; Chawnshang Chang; Charles C.Y. Shih

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Hideji Itokawa

University of North Carolina at Chapel Hill

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Chawnshang Chang

University of North Carolina at Chapel Hill

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Hui-Kang Wang

University of North Carolina at Chapel Hill

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Kuo Hsiung Lee

University of North Carolina at Chapel Hill

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Junko Ishida

Hoshi University

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Charles C.Y. Shih

University of Wisconsin-Madison

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Kuo-Hsiung Lee

Kyoto Pharmaceutical University

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Ching-Yuan Su

Southern Illinois University School of Medicine

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Li Lin

University of North Carolina at Chapel Hill

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Charles C. Y. Shih

University of North Carolina at Chapel Hill

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