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Hiroshi Nishimasu

Massachusetts Institute of Technology

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Featured researches published by Hiroshi Nishimasu.

Archive | 2015

SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION WITH OPTIMIZED FUNCTIONAL CRISPR-CAS SYSTEMS

Silvana Konermann; Alexandro Trevino; Mark D. Brigham; Fei Ran; Patrick Hsu; Chie-yu Lin; Osamu Nureki; Hiroshi Nishimasu; Ryuichiro Ishitani; Feng Zhang

Archive | 2014

Crystal structure of a crispr-cas system, and uses thereof

Feng Zhang; Osamu Nureki; Hiroshi Nishimasu; Ryuichiro Ishitani

Archive | 2016

Engineering and optimization of systems, methods, enzymes and guide scaffolds of cas9 orthologs and variants for sequence manipulation

Feng Zhang; Winston X. Yan; Osamu Nureki; Kaijie Zheng; Le Cong; Hiroshi Nishimasu; Fei Ran; Yinqing Li

The Japanese Biochemical Society/The Molecular Biology Society of Japan | 2017

Structure, dynamics and engineering of CRISPR-Cas9

Hiroshi Nishimasu; Osamu Nureki

The Japanese Biochemical Society/The Molecular Biology Society of Japan | 2017

Generation of tumor-specific CD8+ T-cells via highly efficient CRISPR/Cas9 genome editing

Yasuo Ouchi; Ashwini Patil; Hiroshi Nishimasu; Osamu Nureki; Kenta Nakai; Satoshi Uematsu

The Japanese Biochemical Society/The Molecular Biology Society of Japan | 2017

Structure-based development of genome-editing tools of CRISPR-Cas towards medical applications

Hisato Hirano; Mari Yamada; Takashi Yamano; Hiroshi Nishimasu; Osamu Nureki

Archive | 2017

Structure cristalline de crispr cpf1

Takshi Yamano; Hiroshi Nishimasu; Bernd Zetsche; Ian Slaymaker; Yinqing Li; Iana Fedorova; Kira S. Makarova; Linyi Gao; Eugene V. Koonin; Feng Zhang; Osamu Nureki

Archive | 2017

Crystal structure of crispr cpf1

Takashi Yamano; Hiroshi Nishimasu; Bernd Zetsche; Ian Slaymaker; Yinqing Li; Iana Fedorova; Kira S. Makarova; Linyi Gao; Eugene V. Koonin; Feng Zhang; Osamu Nureki

Archive | 2016

CRISPR-CAS SYSTEMS, CRYSTAL STRUCTURE AND USES THEREOF

Feng Zhang; Osamu Nureki; Hiroshi Nishimasu; Ryuichiro Ishitani

Archive | 2014

Systèmes, procédés et compositions pour manipulation de séquences avec systèmes crispr-cas fonctionnels optimisés

Silvana Konermann; Alexandro E. Trevino; Mark D. Brigham; Fei Ran; Patrick Hsu; Chie-yu Lin; Osamu Nureki; Hiroshi Nishimasu; Ryuichiro Ishitani; Feng Zhang

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