Hisashi Shimada

Synthesis and anti-HIV activity of 4'-substituted 4'-thiothymidines: a new entry based on nucleophilic substitution of the 4'-acetoxy group.

Novel Stereoselective Entry to 2‘-β-Carbon-Substituted 2‘-Deoxy-4‘-thionucleosides from 4-Thiofuranoid Glycals

Nucleophilic substitution approach to 4′-substituted thymidines by employing 4′-benzenesulfonyl leaving group

Synthesis of 4'-Ethynyl-2'-deoxy-4'-thioribonucleosides and Discovery of a Highly Potent and Less Toxic NRTI.

Synthesis of 3′,4′-difluoro-3′-deoxyribonucleosides and its evaluation of the biological activities: Discovery of a novel type of anti-HCV agent 3′,4′-difluorocordycepin

Preparation of 4'-benzenesulfonyl-3'-deoxythymidine and its reaction with organoaluminum and organosilicon reagents.

Self-sacrificing acetylation observed during attempted desilylation of 1-[4-benzenesulfonyl-3-O-(tert-butyldimethylsilyl)-2-deoxy-5-O-methanesulfonyl-α-l-threo-pentofuranosyl]thymine

Reaction of the 4′-benzenesulfonyl derivatives of thymidine with organosilicon and organoaluminum reagents

Synthesis of 4′-substituted cordycepins via benzenesulfenylation at the 4′-position as a key step

Nucleophilic substitution of 4′-acetoxy-4′-thionucleosides: A new access to 4′-substituted 4′-thiothymidines