Hiskias G. Keizer | Researchain

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Featured researches published by Hiskias G. Keizer.

Journal of Medicinal Chemistry | 2004

Synthesis, biological properties, and molecular modeling investigations of novel 3,4-diarylpyrazolines as potent and selective CB1 cannabinoid receptor antagonists

Jos H.M. Lange; Hein K. A. C. Coolen; Herman H. van Stuivenberg; Jessica A. R. Dijksman; A.H.J. Herremans; Eric Ronken; Hiskias G. Keizer; Koos Tipker; Andrew C. McCreary; Willem Veerman; Henri C. Wals; Bob Stork; Peter C. Verveer; Arnold P. den Hartog; Natasja M.J de Jong; Tiny J.P. Adolfs; Jan Hoogendoorn; Chris G. Kruse

Journal of Medicinal Chemistry | 2005

Bioisosteric Replacements of the Pyrazole Moiety of Rimonabant: Synthesis, Biological Properties, and Molecular Modeling Investigations of Thiazoles, Triazoles, and Imidazoles as Potent and Selective CB1 Cannabinoid Receptor Antagonists

Jos H.M. Lange; Herman H. van Stuivenberg; Hein K. A. C. Coolen; Tiny J.P. Adolfs; Andrew C. McCreary; Hiskias G. Keizer; Henri C. Wals; Willem Veerman; Alice J. M. Borst; Wouter de Looff; Peter C. Verveer; Chris G. Kruse

Journal of Medicinal Chemistry | 2005

Synthesis, structure-activity relationships, and biological properties of 1-heteroaryl-4-[ω-(1H-indol-3-yl)alkyl]piperazines, novel potential antipsychotics combining potent dopamine D2 receptor antagonism with potent serotonin reuptake inhibition

Pieter Smid; Hein K. A. C. Coolen; Hiskias G. Keizer; Rolf van Hes; Janpeter de Moes; Arnold P. den Hartog; Bob Stork; Rob H. Plekkenpol; Leonarda C. Niemann; Cees Stroomer; Martin Tulp; Herman H. van Stuivenberg; Andrew C. McCreary; Mayke B. Hesselink; and Arnoud H. J. Herremans; Chris G. Kruse

Journal of Medicinal Chemistry | 2011

N′-(Arylsulfonyl)pyrazoline-1-carboxamidines as Novel, Neutral 5-Hydroxytryptamine 6 Receptor (5-HT6R) Antagonists with Unique Structural Features

Arnold van Loevezijn; Jennifer Venhorst; Wouter I. Iwema Bakker; Cor G. de Korte; Wouter de Looff; Stefan Verhoog; Jan-Willem van Wees; Martijn van Hoeve; Rob P. van de Woestijne; Martina A.W. van der Neut; Alice J. M. Borst; Maria J.P. van Dongen; Natasja M.W.J. de Bruin; Hiskias G. Keizer; Chris G. Kruse

Bioorganic & Medicinal Chemistry Letters | 2008

7-Azaindole derivatives as potential partial nicotinic agonists.

Axel Stoit; Arnold P. den Hartog; Harry Mons; Sjoerd van Schaik; Nynke Barkhuijsen; Cees Stroomer; Hein K. A. C. Coolen; Jan Hendrik Reinders; Tiny J.P. Adolfs; Martina A.W. van der Neut; Hiskias G. Keizer; Chris G. Kruse

Archive | 2007