Hizir Alp

Observation of 95 patients with extradural hematoma and review of the literature

The authors review the cases of 95 patients with extradural hematoma managed at Gazi Hospital in the last 4 years. The common factors in craniocerebral traumas, the time interval between admittance and trauma, the interval between admittance and operation, and the location of hematomas are determined. The arterial origins demonstrated at operation in extradural hematomas are described. The interactions between all these factors and mortality are discussed. Availability of computed tomography scanning accounts for the present mortality rate of 9.4% when compared with the mortality rate of 33% for conventional diagnostic facilities.

Spinal cord compression due to brucella granuloma

SummaryCentral Nervous System (CNS) involvement during the course of Brucella infection is a rare clinical condition. In this article, a patient with a progressive paraparesis syndrome with spasticity, who was treated by medical methods and surgical intervention is analysed. This patient suffered from spinal cord compression in the thoracal region caused by a Brucella granuloma. The patient had no evidence of systemic Brucella infection.ZusammenfassungDie Brucella-Infektion führt nur selten zu einem Befall des Zentralnervensystems. Wir berichten über einen Patienten mit progressiver spastischer Paraparese, bei dem medikamentöse und chirurgische Maßnahmen erfolgten. Die Symptomatik beruhte auf einer Rückenmarkskompression im Thorakalbereich durch ein Brucella-Granulom. Es bestanden keinerlei Symptome einer systemischen Brucella-Infektion.

Vertebral osteoblastoma: are radiologic structural changes necessary for diagnosis?

BACKGROUND A case of osteoblastoma localized at the pedicle of the 10th thoracic vertebra is presented. CASE DESCRIPTION The patient complained of nocturnal back pain not relieved by salycilates, a typical symptom of osteoblastoma. Bone scintigraphy showed a lower thoracic focus of increased osteoblastic activity; however, X-rays, computed tomography, and magnetic resonance images (MRI) were within normal limits, showing only obscure changes that were also noted in the rest of the spine. Repeat MRI with contrast revealed a focal enhancement. After pediculectomy, histopathologic examination confirmed the diagnosis of osteoblastoma. Fifteen months postoperatively, the patient is symptom-free. CONCLUSION Our case demonstrates that some cases of osteoblastoma may not have the classical radiological appearance. Although non-contrast computed tomography and T1-weighted MRI are mildly positive in some instances, osteoblastoma is best visualized on MRI with gadolinium. Like any other neoplasm, osteoblastoma should be detected and removed early, before it can cause structural bony changes.

Giant meningioma in a fourteen-month-old infant

Abstract A case of giant meningioma in a 14-month-old infant is presented and pathologic characteristics of such lesions are reviewed.

Osteoblastoma of the third lumbar vertebra

A case of lumbar osteoblastoma treated surgically is presented. The symptomology, radiologic investigations, pathological features, and surgery of such lesions are reviewed.

Pharmacological and pathophysiological effects of periadventitial stripping on immediate and subacute postoperative vasoconstriction in Guinea pigs

Mechanically induced vasospasm observed in the immediate post-operative period was investigated, and the effect of factors such as temporary clip applications and post-operative intervals were studied. Guinea pig “cervical internal carotid arteries” were used and temporary clips, chosen according to the diameter of the artery and systolic pressure, were applied for a standard period. The same procedure was applied on arteries in which periadventitial tissue had been removed using appropriate microsurgical techniques. On postoperative days 1, 5, and 10, arterial rings were removed while the animals were still alive and Endothelium Dependent Relaxations were measured using a bioassay system. Morphological investigations were also performed using light microscopy on the same arterial preparations.We observed no difference between perioperative and first day postoperative results. The relaxations were minimum. The most striking pathological changes were observed on postoperative day 5, and the relaxation responses began to rise on day 10 together with morphological improvement. It was also found that periadventitial tissue stripping could be used to prevent subacute post-operative vasoconstriction, since its effect was marked on postoperative day 5 and beginned to resolve on day 10.

Double-donor, single-lumen, end-to-side anastomosis

One of the major problems in extracranial-intracranial bypass procedure is the inadequate caliber of the superficial temporal artery branches. In this study, a new end-to-side anastomosis technique that permits two small caliber arteries to be used as a single donor vessel is presented. The external and internal branches of the right common carotid artery were modified to provide a single lumen, and an end-to-side anastomosis was performed between these vessels and the contralateral common carotid artery in 10 rats. One week after the operation, angiography was performed and the patency of anastomoses was demonstrated in 9 of 10 rats.