Toygun Orbay

Late hypoglossal nerve palsy following fracture of the occipital condyle

Fracture of the occipital condyle is a rare problem that can easily be overlooked. We report a patient with occipital condyle fracture who was neurologically intact on admission, and who developed hypoglossal nerve palsy in the late posttraumatic period. The diagnosis was facilitated by the aid of computed tomography.

Clinical significance of acute traumatic intracranial pneumocephalus

Among 1142 patients with head injuries hospitalized in the Neurosurgery Department of Gazi University Medical School during the period between 1979 and 1992, 583 had initial CT scans. A retrospective analysis of these initial CT images revealed intracranial air on admission in only 21 cases. These were classified as acute traumatic intracranial pneumocephalus: a potentially serious complication of head injury.CT scans were re-evaluated so as to reveal whether air was situated in the epidural, subdural, or subarachnoid spaces or intracerebrally; whether associated space-occupying lesions were present; and whether the air bubbles were single or multiple. Clinical data such as the presence of persistant rhinorrhea and/or otorrhea, tension pneumocephalus, severity and type of trauma, and outcome were also assessed to determine the significance of this rare finding.

Vertebral osteoblastoma: are radiologic structural changes necessary for diagnosis?

BACKGROUND A case of osteoblastoma localized at the pedicle of the 10th thoracic vertebra is presented. CASE DESCRIPTION The patient complained of nocturnal back pain not relieved by salycilates, a typical symptom of osteoblastoma. Bone scintigraphy showed a lower thoracic focus of increased osteoblastic activity; however, X-rays, computed tomography, and magnetic resonance images (MRI) were within normal limits, showing only obscure changes that were also noted in the rest of the spine. Repeat MRI with contrast revealed a focal enhancement. After pediculectomy, histopathologic examination confirmed the diagnosis of osteoblastoma. Fifteen months postoperatively, the patient is symptom-free. CONCLUSION Our case demonstrates that some cases of osteoblastoma may not have the classical radiological appearance. Although non-contrast computed tomography and T1-weighted MRI are mildly positive in some instances, osteoblastoma is best visualized on MRI with gadolinium. Like any other neoplasm, osteoblastoma should be detected and removed early, before it can cause structural bony changes.

Giant meningioma in a fourteen-month-old infant

Abstract A case of giant meningioma in a 14-month-old infant is presented and pathologic characteristics of such lesions are reviewed.

Pharmacologic response of endothelium to microvascular temporary clip application

To assess the effects of microvascular temporary clip application on vessel relaxing capability and endothelial substance release, the carotid rings of rats clipped for various durations were studied via bioassay. Noradrenaline and phenylephrine produced an immediate contraction and subsequent relaxation that failed to be suppressed by lysine acetylsalicylate or nicotine in the controls and in the arteries clipped for 0.5, 1, and 5 minutes; however, this relaxation was greatly reduced when the duration was 10 minutes. The results suggest the possible role of inadequate endothelium-derived relaxing factor release following prolonged application of the clips.

Radiological and histopathological examination of early tissue reactions to absorbable hemostatic agents in the rabbit brain

Topical hemostatic agents are widely and safely used in neurosurgery. The purpose of this study was to compare and analyse the early tissue reactions to two hemostatic agents, oxidized regenerated cellulose and gelatin sponge, in rabbit brain by magnetic resonance imaging and histopathologic sections. Bilateral identical parenchymal lesions were made in the frontal regions of each hemisphere in 13 rabbits. Hemostasis was achieved using oxidized regenerated cellulose or gelatin sponge, one agent being used on each side. Cranial magnetic resonance imaging was performed 24 h postoperatively and there was no statistical difference in edema formation at the site of the lesions. Histopathologic examinations indicated that pericapillary edema and endothelial distortion were common in both groups but that there was additional tissue degeneration evident in the regions where gelatin sponge had been used. Oxidized regenerated cellulose seemed to cause greater tissue distortion in magnetic resonance images than gelatin sponge but in contrast, histological examination of lesions in which oxidized regenerated cellulose had been used revealed less tissue degeneration than histopathologic examinations of lesions in which gelatin sponge had been used.

Osteoblastoma of the third lumbar vertebra

A case of lumbar osteoblastoma treated surgically is presented. The symptomology, radiologic investigations, pathological features, and surgery of such lesions are reviewed.

Double-donor, single-lumen, end-to-side anastomosis

One of the major problems in extracranial-intracranial bypass procedure is the inadequate caliber of the superficial temporal artery branches. In this study, a new end-to-side anastomosis technique that permits two small caliber arteries to be used as a single donor vessel is presented. The external and internal branches of the right common carotid artery were modified to provide a single lumen, and an end-to-side anastomosis was performed between these vessels and the contralateral common carotid artery in 10 rats. One week after the operation, angiography was performed and the patency of anastomoses was demonstrated in 9 of 10 rats.