Horst Koch

Treatment of painful neuroma by resection and nerve stump transplantation into a vein.

Twenty-three patients (14 men, 9 women) with 24 painful neuromas underwent resection of neuroma and transposition of the nerve stump into an adjacent vein. The neuromas resulted from amputations (N = 7), tumor excision (N = 5), laceration injuries (N = 4), different types of wrist surgery (N = 3), vein-stripping procedures (N = 2), open fracture of the radius (N = 1), and toe harvest for thumb reconstruction (N = 1). The duration of painful symptoms averaged 66.7 weeks at the time of operation. Average follow-up was 26.5 months. In 22 patients the symptoms improved permanently. Twelve patients experienced complete and permanent relief of pain; some mild degree of pain returned in 8 patients. Two patients experienced moderate pain, and pain recurred unchanged 2 months postoperatively in 1 patient. The results presented are consistent with results of animal experiments demonstrating that typical neuroma does not develop in nerve stumps transposed into veins. Further clinical use of this approach is encouraged.

Reconstruction of combined defects of the Achilles tendon and the overlying soft tissue with a fascia lata graft and a free fasciocutaneous lateral arm flap.

A new approach to reconstruction of the Achilles tendon and overlying soft tissue is presented. A fascia lata graft is used to reconstruct the tendon and is enwrapped by the fascia that is included in a fasciocutaneous lateral arm flap. Five patients were treated with this technique; three of them after surgical Achilles tendon repair, rerupture, and consecutive infection, one after a full-thickness burn with loss of the tendon and one with a history of ochronosis and necrosis of the whole tendon and overlying soft tissue. There were no anastomotic complications and all flaps healed primarily. Functional evaluation with the Cybex II dynamometer was done at least 49 months after reconstruction. A good functional and cosmetic result was obtained in all patients and donor site morbidity was acceptable. These results are well within the results of other surgical treatment options reported in the literature.

Radiofrequency tissue volume reduction of the soft palate and UPPP in the treatment of snoring

The purpose of this study was to evaluate the efficiency of radiofrequency tissue volume reduction (RFTVR) and uvulopalatopharyngoplasty (UPPP) in the treatment of snoring in a prospective clinical trial of 79 patients consecutively undergoing surgery for snoring. Seventy-nine patients with primary snoring or mild OSAS (obstructive sleep apnea syndrome) were enrolled in this clinical trial (66 males and 13 females). According to the anatomical findings (the size of the tonsils and uvula), the patients underwent UPPP/TE of the RFTVR of the soft palate. Forty-seven patients had UPPP/TE (age 45.81±12.11xa0years; median AHI: 8; range 1–29). Thirty-two patients were treated with RFTVR of the soft palate (age 48.10±10.92; median AHI: 5.0; range 0–26). The average number of treatments was 2.2. All patients underwent preoperative polysomnography to exclude severe OSAS. Pre- and postoperative snoring scores were evaluated from the patients with bed partners. Postoperative follow-up data were collected at a median of 4xa0months after treatment; 85.1% of the UPPP group and 53.1% of the RFTVR group underwent postoperative polysomnography. Subjective snoring scores of all study participants were evaluated. Preoperatively, there was no statistically significant difference of subjective symptoms, age and BMI between the two groups. The snoring scores improved statistically significantly in both groups ( P <0.001 in the UPPP group; P =0.001 in the RFTVR group). After UPPP/TE snoring improved in 37 patients (78.7%), and 29 (61.7%) thereof were free of bothersome snoring; no change was found in 9 patients (19.2%), and 1 (2.1%) worsened. In the RFTVR group, snoring improved in 15 (46.9%), and 9 (28.1%) thereof were free of bothersome snoring; no change was found in 13 patients (50%), and 1 worsened (3.1%). Preoperative AHI was statistically higher ( P =0.016) and mean minimal oxygen saturation significantly lower ( P =0.002) in the UPPP group. In the UPPP group AHI and HI showed statistically significant improvement postoperatively ( P =0.025 and P =0.034, respectively). After RFTVR, no statistically significant change of AHI, HI or oxygen saturation was found. Besides limited mucosal erosions (15%) after RFTVR and foreign body sensations (<10%) after UPPP/TE, no side effects were observed. The success rate of RFTVR of the soft palate is lower compared to the more invasive technique of UPPP. Due to its minimally invasive character, RFTVR is suitable as first-step treatment for snoring, but patients should be counseled about possible success rates and different treatment options.

Influence of nerve stump transplantation into a vein on neuroma formation.

The objective of this animal study was to investigate the influence of nerve stump transposition into a vein on neuroma formation. In 24 rats the femoral nerve was severed and the proximal nerve stump was transposed into the lumen of the femoral vein on one side. On the other side, the nerve was severed and left in place. The distal nerve stump was shortened to knee level on both sides. In group 1, the bloodstream was released; in group 2, the segment of the femoral vein containing the nerve stump was excluded from circulation. Histological assessment was performed 8 months later. There were significant differences between the treatment and control sides with respect to neuroma size, endoneural architecture, neural–tissue-to-connective–tissue ratio, and myelination of axons. These data suggest that nerve transposition into a vein could inhibit the formation of classic neuroma.

The Treatment of Painful Neuroma on the Lower Extremity by Resection and Nerve Stump Transplantation Into a Vein

Lower extremity neuroma resection with nerve stump transposition into a vein was employed in eight patients (five male, three female). The neuromas resulted from amputations (four patients), vein stripping procedures (two patients), tumor resection, and toe-harvest for thumb reconstruction. Follow-up averaged 17 months (range, 8-37). Four of the patients experienced complete and permanent relief of pain; in three patients mild pain recurred within 3 months. All of these patients were satisfied with the result and did not request further treatment. In one case, a painful neuroma recurred. Our results suggest the possibility of inhibiting the formation of painful neuromas by nerve transposition into a vein. Further use of this method is encouraged.

SALVAGE OF AN ISCHAEMIC LOWER LIMB AND A FREE FLAP WITH AN ARTERIAL Y-GRAFT: Case report

A defect of the lower limb was treated with a scapular free flap. An end-to-side anastomosis was made to the posterior tibial artery, which was the single perfusing artery of the foot. When it thrombosed, the problem was solved successfully with an arterial Y-graft.A defect of the lower limb was treated with a scapular free flap. An end-to-side anastomosis was made to the posterior tibial artery, which was the single perfusing artery of the foot. When it thrombosed, the problem was solved successfully with an arterial Y-graft.

Clinical experience with a tensor fasciae latae perforator flap based on septocutaneous perforators

BACKGROUNDnBased on an anatomical study of the perforators of the tensor fasciae latae (TFL) perforator flap, a clinical study was undertaken to confirm our data in a clinical trial and to demonstrate the ability to harvest a TFL perforator flap on septocutaneous perforators.nnnMETHODSnA retrospective case series analysis was performed of patients, who had undergone reconstruction of soft-tissue defects of the extremities, the groin and the head in 17 cases with a TFL perforator flap based on septocutaneous perforators; in three cases, a combined flap was used. The size of the flaps, the number of perforators, their external diameter, the length of the pedicle and the location and the distance from the anterior superior iliac spine (ASIS) were recorded.nnnRESULTSnThe average number of septocutaneous perforators per flap was 1.3 (range, 1-3); the average distance from the ASIS was 11xa0cm (range, 8-14xa0cm). The pedicle length varied between 4 and 10xa0cm, with an average of 7xa0cm; the average diameter of the pedicle was 4xa0mm (range, 1-5xa0mm). The average length of the flaps was 14xa0cm (range, 4.5-25), and the average width was 7xa0cm (range, 4.5-19). Donor site closure was achieved by direct closure in 14 patients, and in three patients with a split-thickness skin graft. In one case, at least two-thirds of the flap became necrotic because the septocutaneous perforator was located too far laterally from the flap centre. In one case of a combined flap, one skin island became partly necrotic due to compression after the pedicle was placed beneath the tendon of the extensor tibialis anterior muscle. One flap was successfully revised after venous thrombosis.nnnCONCLUSIONSnThe reliability and consistency of the septocutaneous perforators of the TFL flap make planning of this flap easy and the dissection straightforward. Although the number of complications is high in this series, only one complication is related to the flap and the planning itself. With the proposed modifications, we recommend this flap as an interesting alternative to other fasciocutaneous flaps.

The posterior interosseous artery flap: Clinical results with special emphasis on donor site morbidity

This study evaluated the clinical results, and especially the donor site morbidity of the posterior interosseous artery flap. A retrospective study included 40 patients with defects covered with posterior interosseous flaps. Twenty-one patients were available for a follow-up examination to assess donor site morbidity by evaluating the dimensions and quality of the donor site scar and the forearm contour as well as complaints and subjective satisfaction with the aesthetic result. The flaps and related donor sites healed uneventfully in 29 cases (72.5%); healing was delayed in 11 cases (27.5%), with total flap loss in two cases. Further surgery was required in six cases. The quality of the donor site scar rated with the Vancouver Scar Scale averaged 2.4 points. Eleven patients (55%) reported impaired sensibility around the donor site and four patients (20%) had physical complaints. Subjective and objective donor site evaluation revealed significantly lower donor site morbidity for directly closed as opposed to skin grafted donor sites, although subjectively, there was a high level of satisfaction in both groups. Our data indicated that the posterior interosseous flap is a valuable option for the management of soft-tissue defects on the dorsum of the hand, due to its anatomical reliability and soft and pliable tissue, its low donor site morbidity and high patient acceptance.

First Experience Using Contrast‐enhanced Ultrasound to Evaluate Vascularisation of Acellular Dermal Matrices after Implant‐Based Breast Reconstruction

Acellular dermal matrices (ADM) have been used frequently in therapeutic and prophylactic breast procedures. To date there have been no reports on vascularisation of ADMs and formation of tissue around them as seen with modern non‐invasive imaging techniques such as contrast‐enhanced ultrasound (CEUS). In this case series, we used CEUS to investigate the features of ADM in relation to vascular ingrowth and scaffold for “new” tissue formation. This is a retrospective evaluation of patients who underwent successful skin‐ and nipple‐sparing mastectomy (SSM, NSM) with immediate IBBR using ADM from May 31, 2010, through December 28, 2012. Over a 24‐month period, 16 patients, with an average age of 44 years (range 27–70 years), were evaluated with CEUS. No contrast agent allergies or side effects were reported for the ultrasound examination. After contrast agent injection (1–18 months postoperatively), homogeneous normal enhancement in the ADM and peripheral region with physiological tissue formation was seen in all patients. In this small study, the most obvious contribution of CEUS is the in vivo evaluation of vascular ingrowth and tissue formation after IBBR with ADM after follow‐up of 1–18 months postoperatively.

New Synthetic Prosthesis for Peripheral Nerve Injuries An Experimental Pilot Study

Introduction. Even the most modern technology has failed to induce satisfactory functional regeneration of traumatically severed peripheral nerves. Delayed neural regeneration and in consequence, slower neural conduction seriously limit muscle function in the area supplied by the injured nerve. This study aimed to compare a new nerve coaptation system involving an innovative prosthesis with the classical clinical method of sutured nerve coaptation. Besides the time and degree of nerve regeneration, the influence of electrostimulation was also tested. Methods. The sciatic nerve was severed in 14 female Göttingen minipigs with an average weight of 40.4 kg. The animals were randomized into 2 groups: One group received the new prosthesis and the other underwent microsurgical coaptation. In each group, according to the randomization a part of the animals received postoperative electrostimulation. Postoperative monitoring and the stimulation schedule covered a period of 9 months, during which axonal budding was evaluated monthly. Results. The data from the pilot study indicate that results with the nerve prosthesis were comparable with those of conventional coaptation. Conclusion. The results indicate that implantation of the nerve prosthesis allows for good and effective neural regeneration. This new and simple treatment option for peripheral nerve injuries can be performed in any hospital with surgical facilities as it does not involve the demanding microsurgical suture technique that can only be performed in specialized centers.