Humaira Bashir

Coexistent Papillary Carcinoma of Thyroid and Hashimoto's Thyroiditis - Diagnosis on Fine Needle Aspiration Cytology

Hashimoto’s thyroiditis is associated with an increased risk of developing papillary carcinoma of thyroid. We hereby report a case of Hashimoto’s thyroiditis with papillary carcinoma in a 45-year-old ear old female diagnosed on fine needle aspiration cytology (FNAC) which was later confirmed on histopathological examination .Such an occurrence, when both lesions are picked up on FNAC in a patient with no palpable thyroid nodule is rare. The case is presented here for its rarity.

Primary paratesticular carcinoid in a 70-year-old male.

Carcinoid tumors are neuroendocrine tumors and most frequently occur within tissues derived from the embryonic gut. These tumors can occur in any organ but are very rare in the paratesticular region. We hereby report a case of paratesticular carcinoid in a 70-year-old male who, to the best of our knowledge, is the oldest patient reported so far in the world literature.

Clinicopathological pattern of cranial unifocal Langerhans cell histiocytosis: A study at medical college hospital

Background: Eosinophilic granuloma (EG) of bone refers to a generally benign form of Langerhans cell histiocytosis localized to the bone. Patients may present with a solitary lesion (monostotic) or multiple sites of involvement (polyostotic). Materials and Methods: This study was done to evaluate the clinicopathological pattern of 6 cases of EGs of the skull diagnosed at a tertiary care hospital. All patients of EG were included with the help of medical records over a 5-year period that is, November 2009 to November 2014. They all had been preoperatively evaluated by skull X-ray and computed tomography. To rule out a multifocal disease scintigraphy was performed in all cases preoperatively. Surgical excision was performed, and EG was diagnosed on histopathology and immunohistochemistry. Results: There was a male predominance. Parietal bone was the most common affected bone. Total excision of the lesion was performed in all cases. No patient received postoperative radiotherapy. The follow-up period ranged from 6 months to 3 years. No tumor recurrence was noted. Conclusion: With an unknown etiology, nonspecific clinical and radiological findings with diagnosis possible only on histopathological examination, EG needs to be considered in the differential diagnosis as a skull mass, especially in children.

Synchronous Primary Adenocarcinoma and Gastrointestinal Stromal Tumor of Stomach: A Case Report and Review of Literature

A synchronous occurrence of epithelial and gastrointestinal stromal tumors (GISTs) in the stomach is unusual. The association has often been detected incidentally and it is not known whether such an association is a simple incidental coexistence or there is a causal relationship between the two lesions. We hereby report a 70-year-old male operated for adenocarcinoma of stomach who, besides the primary lesion in the lesser curve, had another lesion i.e., GIST on the serosal aspect of antrum picked up on gross examination of the specimen. The tumor was GIST of low risk category which was positive for tumor markers CD117 (C-kit) and CD34. The case is presented here for its rarity.