I. Abu-El-Naaj

Odontogenic myxoma – A case series and review of the surgical management

BACKGROUND Odontogenic myxomas (OMs) are considered to be a benign odontogenic tumour with locally aggressive behaviour. Since these neoplasms are rare in the oral cavity, the possible surgical management can be quite variable. Literature recommendation can vary from simple curettage and peripheral ostectomy up to segmental resection. CASE REPORTS In the present article, a series of three new cases are presented and discussed. The first case is a 43-year-old male presented with a relatively large OM in the left maxillary area. The second case is a 37-year-old female presented with a relatively smaller left maxillary swelling that was diagnosed as OM. The third and final case is a 52-year-old male presented with a large OM of the right mandibular molar area. The surgical management that was chosen in each case is discussed. CONCLUSION In the present manuscript, a short review of the current literature on the surgical management of OMs is presented with a review of three cases of oral OMs that were treated in our department, followed by a discussion of the treatment options in each case.

Prognostic value of heparanase expression and cellular localization in oral cancer.

Metastases formation depends on the ability of tumor cells to invade basement membranes in a process involving enzymes capable of degrading extracellular matrix components.