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Dive into the research topics where Micha Peled is active.

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Featured researches published by Micha Peled.


Journal of Oral and Maxillofacial Surgery | 2010

Superficial Parotidectomy Versus Retrograde Partial Superficial Parotidectomy in Treating Benign Salivary Gland Tumor (Pleomorphic Adenoma)

Omri Emodi; Imad Abu El-Naaj; Arye Gordin; Sharon Akrish; Micha Peled

PURPOSE Of all benign salivary gland tumors of the parotid gland, pleomorphic adenoma (mixed tumor) is the most common. It accounts for 60% to 70% of all benign tumors of the parotid gland. This neoplasm arises in patients in the fourth to sixth decade of life, with a female predominance. The surgical excision of this lesion continues to be the subject of major debate. The goal is to avoid facial disability yet attain complete resection without perforation of the capsule/pseudocapsule. The purpose of our study is to compare 2 surgical techniques performed at the Ear, Nose, and Throat and Maxillofacial Departments, Rambam Medical Center, Haifa, Israel, and determine which is preferable in treating this lesion. PATIENTS AND METHODS We reviewed 48 patients who underwent excision of pleomorphic adenoma of the parotid gland between 1996 and 2005 at Rambam Medical Center: 18 were treated surgically with the classical superficial parotidectomy (SP) technique, using an anterograde approach, and 30 were treated with retrograde partial superficial parotidectomy (PSP). We compared the 2 surgical techniques in terms of surgical time, histopathologic size of the lesion, amount of excised healthy parotid tissue, histologic margin, and the preservation of the capsule/pseudocapsule. We also made clinical records of temporary or definitive injury to the facial nerve, which branches of the facial nerve were temporarily or definitively injured, the occurrence of Frey syndrome, esthetic satisfaction, and the amount of recurrence or infection after surgery. RESULTS Of the 48 patients, 19 (39.6%) were male and 29 (60.4%) were female, with a mean age (+/- SD) of 43.8 +/- 16.97 years (median, 50 years; range, 12-79 years). We found a significant difference (P = .029) in mean surgical time (+/- SD): 171 +/- 49.7 minutes (median, 165 minutes) when performing the classical SP and 145 +/- 42.7 minutes (median, 130 minutes) when performing the retrograde PSP. Much more healthy parotid tissue was taken out with the classical procedure (mean, 51.4 +/- 13.6 mm; median, 50 mm) than with the retrograde PSP technique (mean, 39.2 +/- 11.8; median, 35 mm) (P = .01). There was a significant difference (P = .0003) in facial nerve injuries: 39% of patients did not report any facial deficit in the SP group compared with 90% in the PSP group. In the SP group, only 3 patients reported a permanent deficit, and in the PSP group, only 3 patients had a temporary deficit (compared with 8 in the SP group). The main injuries occurred in the mandibular branch with both techniques: 6 SP and 2 PSP. There was no difference in esthetic satisfaction: 72.2% of patients in the SP group and 80% in the PSP group had no esthetic complaints. In the SP group, patients mainly complained about swelling (3 patients), and in the retrograde PSP group, the main complaint was depression (4 patients). Frey syndrome was found in 9 patients in the retrograde PSP group and 4 in the classical SP group (with an overall rate of 27.7%). The lesion recurred in only 2 patients--1 in each group. CONCLUSION With both of the techniques, we found satisfactory results. In the majority of cases, retrograde PSP is a superior technique to the classical SP, although Frey syndrome is more often observed with the former.


Journal of Oral and Maxillofacial Surgery | 2010

Chronic Obstructive Parotitis Due to Strictures of Stenson's Duct—Our Treatment Experience With Sialoendoscopy

Leon Ardekian; Dror Shamir; Meara Trabelsi; Micha Peled

PURPOSE The present retrospective analysis was performed to assess the effectiveness of sialoendoscopic treatment of chronic obstructive parotitis. MATERIALS AND METHODS The study group included 87 parotid glands with stricture as the only cause of gland obstruction. After sialographic and sialoendoscopic evaluation, sialoendoscopic 4-step surgical treatments were performed. The treatment protocol was designed. RESULTS Sialoendoscopy proved to be a successful procedure in 94.7% of the affected parotid glands we treated. CONCLUSION The minimally invasive technique of sialoendoscopy for treatment of strictures of the salivary glands could be a welcome innovation, helping to avoid radical surgical treatment of salivary gland disease.


Journal of Oral and Maxillofacial Surgery | 2011

Polymorphous Low Grade Adenocarcinoma: Case Series and Review of Surgical Management

Imad Abu El-Naaj; Yoav Leiser; Amir Wolff; Micha Peled

PURPOSE The aim of the present study was to review the published data regarding the management of polymorphous low-grade adenocarcinoma (PLGA) and present our experience in the treatment of patients diagnosed with PLGA. MATERIALS AND METHODS We performed a review of the published data of the treatment possibilities for PLGA, and report on a case series of 4 patients diagnosed with palatal PLGA. RESULTS The mean age at diagnosis was 61.75 years. All cases were localized on the hard palate. The male/female ratio was 1:3. One patient had an ulcerative painful lump. In correlation with the published data, most of our patients presented initially with a diagnosis that was not conclusive for the presence of PLGA. The most common initial diagnostic findings were adenoid cystic carcinoma and pleomorphic adenoma. The treatment of choice was surgical excision of the tumor with safe margins of 1.5 cm. One patient had a positive cervical lymph node metastasis and underwent an elective neck dissection followed by radiotherapy. Local recurrence was diagnosed in 1 patient 6 years after the surgical management. Most cases were reconstructed using an obturator, except for 1 patient who underwent reconstruction using the temporalis myofascial flap. CONCLUSIONS PLGA is a slow-growing, distinct, uncommon neoplasm of the minor salivary glands. Because it is characterized by a diverse morphologic pattern that resembles adenoid cystic carcinoma or pleomorphic adenoma, the initial diagnosis is usually inconclusive. Until a final diagnosis has been made, we believe that the reconstruction possibilities should be mainly obturators to allow a good visualization of the surgical site. The use of microvascular free flaps or rotational flaps should be reserved to patients with clearer pathologic diagnosis.


Head and Neck-journal for The Sciences and Specialties of The Head and Neck | 2011

Prognostic value of heparanase expression and cellular localization in oral cancer.

Yoav Leiser; I. Abu-El-Naaj; Edmond Sabo; Sharon Akrish; Neta Ilan; Ofer Ben-Izhak; Micha Peled; Israel Vlodavsky

Metastases formation depends on the ability of tumor cells to invade basement membranes in a process involving enzymes capable of degrading extracellular matrix components.


Journal of Oral and Maxillofacial Surgery | 2014

Lymphoepithelial Carcinoma—Review of the Treatment Modalities and Report of a Rare Case in the Sublingual Gland

Yoav Leiser; Micha Peled; Amir Wolff; Imad Abu El-Naaj

Controversies exist in the current literature regarding the treatment of lymphoepithelial carcinoma (LEC). The presented study summaries the literature controversies in the treatment of LEC and present a case of a rare LEC diagnosed in the sublingual gland of an otherwise healthy 21-year-old Arab woman. The patient was admitted for swelling in the sublingual area. A biopsy indicated a diagnosis of LEC of the sublingual gland. Treatment included a wide resection with safe margins, marginal mandibulectomy, functional neck dissection, and a radial forearm free flap for reconstruction. The patient received concomitant radiotherapy and has remained disease free since her last follow-up. The recommended primary treatment, based on the literature review, is primary surgical excision with neck dissection and optional adjuvant radiotherapy to the gland area. Chemotherapy was not found to be beneficial according to the literature.


Journal of Cranio-maxillofacial Surgery | 1999

Burkitt's lymphoma of the oral cavity in Israel

Leon Ardekian; Adi Rachmiel; Daren Rosen; I. Abu-El-Naaj; Micha Peled; Dov Laufer


Journal of Oral and Maxillofacial Surgery | 2011

Incidence of oral cancer occult metastasis and survival of T1-T2N0 oral cancer patients.

Imad Abu El-Naaj; Yoav Leiser; Myrela Shveis; Edmond Sabo; Micha Peled


Dental Traumatology | 2007

Dento-alveolar and maxillofacial injuries - a retrospective study from a level 1 trauma center in Israel.

Shaul Lin; Liran Levin; Sharon Goldman; Micha Peled


International Journal of Paediatric Dentistry | 2001

Orbital infection arising from a primary tooth: a case report

Daren Rosen; Leon Ardekian; I. Abu El-Naaj; D. Fischer; Micha Peled; Dov Laufer


Journal of Oral and Maxillofacial Surgery | 2011

Sialolipoma of the Salivary Gland: Two New Cases, Literature Review, and Histogenetic Hypothesis

Sharon Akrish; Yoav Leiser; Dror Shamira; Micha Peled

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Yoav Leiser

Rappaport Faculty of Medicine

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I. Abu-El-Naaj

Technion – Israel Institute of Technology

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Imad Abu El-Naaj

Rappaport Faculty of Medicine

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Leon Ardekian

Technion – Israel Institute of Technology

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Sharon Akrish

Rappaport Faculty of Medicine

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Daren Rosen

Technion – Israel Institute of Technology

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Dov Laufer

Rappaport Faculty of Medicine

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Edmond Sabo

Technion – Israel Institute of Technology

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Adi Rachmiel

Rappaport Faculty of Medicine

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Arye Gordin

Rappaport Faculty of Medicine

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