I. Kabore

A substituted 1-azaadamantane derivative by “one pot” cyclisation of monocyclic monoterpenoids

Abstract Cyclisation of monocyclic amines via iminium intermediates provides a facile synthesis of a substituted 1-azaadamantane derivative.

Alcaloïdes stéroïdiques ☆: CXL. Trois nouveaux aminodésoxyglyco-stéroïdes isolés des feuilles de L'holarrhena antidysenterica (Roxb.) wall. : l'holarosine b et les holantosines e et f. Un nouveau sucre aminé, la D-holacosamine

Abstract Holarosine B, 3β-(4-amino-2,4,6-trideoxy-3- O -methyl-β- D - ribo -hexopyranosyl) oxy-14β-hydroxy-5α,17βH-card-20(22)-enolide, and holantosines E and F have been isolated from H. antidysenterica leaves. Holantosines E and F are β- D -glycosides of a new amino sugar, D -holacosamine or 4-amino-4-deoxy-sarmentose, and holantogenine or anhydroholantogenine.

Acid-catalysed decomposition of (20 R) and (20 S)-20-azido-5α-pregnane : bis steroids Schiff base formation via imine coupling.

Abstract BF 3 -OEt 2 decompostion of azides 1 or 2 leads to the coupling product Schiff base 6 via imine intermediates.