I. S. Farrukh | Researchain

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Journal of Cardiovascular Pharmacology | 1987

The Effect of Treatment with Nitrendipine and Other Calcium Channel Blockers on the Physiologic and Pathologic Changes Caused by Hypoxia in Rats

J. R. Michael; Thomas P. Kennedy; Philip Buescher; I. S. Farrukh; Peter Rock; G. H. Gurtner; Suzanne M. de la Monte; Grover M. Hutchins

Nitrendipine and other calcium channel blokers acutely inhibit hypoxic pulmonary vasoconstriction and show promise in the prevention of the pulmonary vascular and cardiac changes produced by chronic alveolar hypoxia. This paper reviews the current information available from animal and clinical studies.

Journal of Applied Physiology | 1987

Pharmacological modification of pulmonary vascular injury: possible role of cAMP

I. S. Farrukh; G. H. Gurtner; J. R. Michael

Journal of Applied Physiology | 1985

Thromboxane-induced pulmonary vasoconstriction: involvement of calcium

I. S. Farrukh; J. R. Michael; Warren R. Summer; N. F. Adkinson; G. H. Gurtner

The American review of respiratory disease | 1988

The Role of Cyclooxygenase and Lipoxygenase Mediators in Oxidant-induced Lung Injury

I. S. Farrukh; J. R. Michael; Stephen P. Peters; A. M. Sciuto; N. F. Adkinson; H. S. Freeland; A. Paky; Ernst W. Spannhake; Warren R. Summer; G. H. Gurtner

The American review of respiratory disease | 1987

The role of arachidonate mediators in peroxide-induced lung injury.

G. H. Gurtner; I. S. Farrukh; N. Franklin Adkinson; A. M. Sciuto; Jane M. Jacobson; J. R. Michael

The American review of respiratory disease | 1985

Isoproterenol or aminophylline attenuate pulmonary edema after acid lung injury.

Irving Mizus; Warren R. Summer; I. S. Farrukh; John R. Michael; G. H. Gurtner

Journal of Applied Physiology | 1989

Effect of pH on pulmonary vascular tone, reactivity, and arachidonate metabolism

I. S. Farrukh; G. H. Gurtner; P. B. Terry; W. Tohidi; J. N. Yang; N. F. Adkinson; J. R. Michael

The American review of respiratory disease | 1986

Nitrendipine attenuates the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia in rats.

J. R. Michael; Thomas P. Kennedy; Philip Clay Buescher; I. S. Farrukh; Robert F. Lodato; Peter Rock; J. Gottlieb; G. H. Gurtner; S. M. de la Monte; Grover M. Hutchins

The American review of respiratory disease | 1986