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Ian T. Harrison

Stanford University

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Publication

Featured researches published by Ian T. Harrison.

Scandinavian Journal of Rheumatology | 1973

Structure Activity Relationship Among 6-Substituted-2-Naphthylacetic Acids: A New Series of Nonsteroidal Anti-inflammatory Agents

J. H. Fried; Ian T. Harrison; B. Lewis; J. Riegl; W. Rooks; A. Tomolonis

Chemical modification of 2-naphthylacetic acid has led to (+)-2-(6-methoxy-2-naphthyl)-propionic acid, naproxen. Maximal biological activity in the naph-thylpropionic acid series is associated with the S absoiuti configuration. In experimental animals naproxen shows anti-inflammatory, analgetic and antipyretic activity o: llxphenylbutazone, and 7 and 22xacetylsalicylic acid re spectively. It is noteworthy that highly active compound! were obtained without resorting to nitrogenous substitu cnts.

Journal of Medicinal Chemistry | 1970

Nonsteroidal antiinflammatory agents. I. 6-substituted 2-naphthylacetic acids.

Ian T. Harrison; Brian. Lewis; Peter H. Nelson; Wendell H. Rooks; Adolph P. Roszkowski; Albert J. Tomolonis; John H. Fried

Journal of Organic Chemistry | 1970

Procedure for the methylenation of olefins to cyclopropanes

Robert J. Rawson; Ian T. Harrison

Archive | 1973

2-(6{40 -Methoxy-2{40 -naphthyl)acetic acid

John H. Fried; Ian T. Harrison

Journal of Organic Chemistry | 1968

Synthesis of (+-)-zearalenone

Isidoros Vlattas; Ian T. Harrison; Laszlo Tokes; John H. Fried; Alexander D. Cross

Archive | 1975

2-(6'-Methoxy-2'-naphthyl)acetic acid

John H. Fried; Ian T. Harrison

Archive | 1975

2-(6-Substituted-2'-naphthyl) acetic acid derivatives and the salts and esters thereof

John H. Fried; Ian T. Harrison

Archive | 1975

Anti-inflammatory, analgesic, anti-pyretic and anti-pruritic 6-substituted 2-naphthyl acetic acid derivative-containing compositions and methods of use thereof

John H. Fried; Ian T. Harrison

Archive | 1975

2-naphthyl acetic acid derivatives and compositions and methods thereof

John H. Fried; Ian T. Harrison

Journal of Organic Chemistry | 1977

Synthesis of holomycin and derivatives.

John E. Ellis; John H. Fried; Ian T. Harrison; Erich Rapp; Carl H. Ross

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John H. Fried

Merck

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Stefan H. Unger

Pomona College

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Wendell H. Rooks

Worcester Foundation for Biomedical Research

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A. Tomolonis

Stanford University

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B. Lewis

Stanford University

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Carl H. Ross

Stanford University

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Erich Rapp

Stanford University

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J. H. Fried

Stanford University

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J. Riegl

Stanford University

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Joan M. Caroon

Hoffmann-La Roche

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