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Dive into the research topics where Ik Joon Choi is active.

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Featured researches published by Ik Joon Choi.


Laryngoscope | 2015

Pediatric tracheostomy revisited: A nine-year experience using horizontal intercartilaginous incision

Jae-Jin Song; Ik Joon Choi; Hyun Chang; Dong Wook Kim; Hyung W. Chang; Gyeong-Hun Park; Min‐Su Kim; Myung Whun Sung; J. Hun Hah

To describe our tracheostomy procedure using a vertical skin incision and a horizontal intercartilaginous incision and to compare our postoperative results with those in the recent literature.


Head and Neck-journal for The Sciences and Specialties of The Head and Neck | 2016

Comparison of quality of life between open and endoscopic thyroidectomy for papillary thyroid cancer

Myung Chul Lee; Hoon Park; Byeong-Cheol Lee; Guk-Haeng Lee; Ik Joon Choi

Recently, various endoscopic thyroidectomy techniques have been introduced for cosmetic purposes. However, few reports have compared the quality of life (QOL) between post–endoscopic thyroidectomy and post–conventional open thyroidectomy. In this study, we investigated whether endoscopic thyroidectomy was comparable to conventional open thyroidectomy with respect to QOL.


Head and Neck-journal for The Sciences and Specialties of The Head and Neck | 2013

New endoscopic thyroidectomy via a unilateral axillo‐breast approach with gas insufflation: Preliminary report

Myung-Chul Lee; Jeong‐A Mo; Ik Joon Choi; Byung-Chul Lee; Guk-Haeng Lee

Invasiveness of endoscopic thyroidectomy has been in debate. The purpose of this study was to introduce new endoscopic thyroidectomy via a unilateral axillo‐breast approach (UABA) with gas insufflation to lessen invasiveness.


Histopathology | 2017

Expression of activated Notch1 and HEY1 in papillary thyroid carcinoma.

Chang Won Jung; Jun Suk Kong; Hyesil Seol; Sunhoo Park; Jae Soo Koh; Seung-Sook Lee; Min Joo Kim; Ik Joon Choi; Jae Kyung Myung

The Notch signalling pathway is involved in normal development as well as tumorigenesis. However, it is unclear whether Notch activation is related to diverse clinicopathological factors in papillary thyroid carcinoma (PTC).


Head and Neck-journal for The Sciences and Specialties of The Head and Neck | 2014

Comparative study of a gasless transaxillary approach versus a bilateral axillo‐breast approach for endoscopic thyroidectomy in a single institute

Myung-Chul Lee; Hoon Park; Ik Joon Choi; Byeong-Cheol Lee; Guk-Haeng Lee

Gasless transaxillary approach (TA) and the bilateral axillo‐breast approach (BABA) are 2 distinctive approaches for endoscopic thyroidectomy. The purpose of this study was to evaluate and compare these 2 procedures.


Oncotarget | 2017

Immuno-PET imaging based radioimmunotherapy in head and neck squamous cell carcinoma model

In Ho Song; Youn Noh; Junhye Kwon; Jae Ho Jung; Byung-Chul Lee; Kwang Il Kim; Yong Jin Lee; Joo Hyun Kang; Chae Seo Rhee; Chul Hee Lee; Tae Sup Lee; Ik Joon Choi

The epidermal growth factor receptor (EGFR) is one of the most comprehensively studied molecular targets in head and neck squamous cell carcinoma (HNSCC). However, inherent and acquired resistance are serious problems and are responsible for limited clinical efficacy and tumor recurrence. In this study, we evaluated the feasibility of immuno-positron emission tomography (PET) imaging and radioimmunotherapy (RIT) with 64Cu-/177Lu-PCTA-cetuximab in cetuximab-resistant SNU-1066 HNSCC xenografted model. The cellular uptake of 64Cu/177Lu-3,6,9,15-tetraazabicyclo[9.3.1]-pentadeca-1(15),11,13-triene-3,6,9,-triacetic acid (PCTA)-cetuximab showed good correlation with western blot and flow cytometry analysis in EGFR expression level of various HNSCC cells. 177Lu-PCTA-cetuximab selectively killed cetuximab-resistant SNU-1066 cells in vitro. 64Cu-/177Lu-PCTA-cetuximab specifically accumulated in SNU-1066 tumor and those uptakes were peaked at 48 h and 7 day, respectively in biodistribution, PET and single-photon emission computed tomography/computed tomography (SPECT/CT) imaging. RIT with single dose of 177Lu-PCTA-cetuximab exhibited significant tumor regression and markedly reduced 2-[18F]fluoro-2-deoxy-D-glucose (18F-FDG) uptake, compared to other groups. Proliferation index were dramatically decreased and apoptotic index increased in RIT group. These results suggest that a diagnostic and therapeutic convergence radiopharmaceutical, 64Cu-/177Lu-PCTA-cetuximab has the potential of target selection using immuno-PET imaging and targeted therapy by RIT in EGFR expressing cetuximab-resistant HNSCC tumors.


Laryngoscope | 2016

Endolaryngeal suture technique using a silicon piece: A fast and convenient method.

Tack-Kyun Kwon; Ye Ji Shim; Hee Young Son; Ik Joon Choi

INTRODUCTION An endolaryngeal microsuture is one of the mandatory surgical techniques for most laryngological surgeons. It is required in many types of operations, such as vocal fold laceration repair, closure of a large endolaryngeal surgical defect, closure of a micropocket for implantation in vocal fold scar surgery, submucosal arytenoidectomy, flap suture in posterior glottis stenosis surgery, and many other microlaryngeal surgeries. The endolaryngeal microsuture technique has typically been reported with a focus on the knotting technique, such as the Indian tie, rather than a focus on the needling technique. There are many microinstruments, including laryngeal needle holders and curved alligator forceps, designed specifically for microsuture techniques. However, despite the use of such microinstruments, suturing of vocal folds, which involves handling of needles 20 cm apart from the hands with instruments in a limited working space, is still a challenging task for many laryngologists. Here, we report a better way to handle the needles using a silicon piece when performing an endolaryngeal microsuture, and evaluate the efficacy by having inexperienced surgeons try this new technique.


Otolaryngology-Head and Neck Surgery | 2008

S225 – A New Meatoplasty Technique in Canal Wall Down

Kwang-Hyun Kim; Ik Joon Choi; Sun O Chang; Jae-Jin Song; Junho Lee; Seung-Ha Oh; Chong Sun Kim

Objectives Although it is well recognized that a small meatus after canal wall down tympanomastoidectomy can cause a lifetime problem, unsatisfactory results are frequently encountered. We introduce a new technique to maintain a large external auditory meatus, reduce the mastoid dead space, and improve the posterior auricular cosmetics outcome. Methods From Jan 2005 through Dec 2006, 39 ears had undergone canal wall down tympanomastoidectomy with the perichondreial posterior fixation technique. 2 stitches were made to pull the perichondrium of the canvun conchal cartilage posteriorly to the periostium of the mastoid bone. Medical records were retrospectively reviewed for the postoperative complications, including infection. Postoperative size of the meatus and the extent of cavum conchal cartilage burying into the mastoid cavity were evaluated by taking digital photographs. Results 15 males and 24 females were included; the mean age was 54 years (37yr-66yr). The postoperative follow-up duration was 9.5 months (6mo-23mo) in average. All the ears maintained a clean and large external meatus. The posterior auricular cavum conchal cartilage was successfully prevented from being buried into the mastoid cavity in all the ears. The extent of burying was much improved compared to the conventional technique. 2 ears (5%) had a very mild postoperative inflammation but it was easily controlled by topical antibiotics. Conclusions The perichondreial posterior fixation, which is a new meatoplasty technique in canal wall down tympanomastoidectomy, seems to be effective in maintaining a large external auditory meatus and improving the cosmetic outcome with minimal risk of complications.


International Journal of Clinical and Experimental Pathology | 2015

Expression of cancer stem cell markers and epithelial-mesenchymal transition-related factors in anaplastic thyroid carcinoma

Chang Won Jung; Kang Hee Han; Hyesil Seol; Sunhoo Park; Jae Soo Koh; Seung-Sook Lee; Min Joo Kim; Ik Joon Choi; Jae Kyung Myung


Korean Journal of Otorhinolaryngology-head and Neck Surgery | 2008

Clinical Manifestations and Surgical Results of Malleostapedotomy and Malleostapedectomy

Kyung Tae Park; Myung-Whan Suh; Jae-Jin Song; Chang-Hee Kim; Ik Joon Choi; Dong Wook Kim; Junho Lee; Seung-Ha Oh; Sun O Chang

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Myung-Chul Lee

Seoul National University Hospital

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Jae-Jin Song

Seoul National University Bundang Hospital

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Min Joo Kim

Seoul National University

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Dong Wook Kim

Seoul National University Hospital

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Guk Haeng Lee

Seoul National University

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Hyesil Seol

Seoul National University Hospital

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