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Ikuo Watanabe

Okayama University

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Publication

Featured researches published by Ikuo Watanabe.

Chemical & Pharmaceutical Bulletin | 1997

Syntheses and antifungal activities of dl-griseofulvin and its congeners. I.

Yasuo Takeuchi; Ikuo Watanabe; Keiji Misumi; Mari Irie; Yoko Hirose; Kazumi Hirata; Masatoshi Yamato; Takashi Harayama

Chemical & Pharmaceutical Bulletin | 1999

An Acid-Catalyzed O, N-Acyl Migration and Application to the Synthesis of N-(4-Isopropyl-2, 2-dimethyl-3-oxo-3, 4-dihydro-2H-benzo[1, 4]oxazine-6-carbonyl) guanidine Methanesulfonate (KB-R9032), a Novel Na/H Exchange Inhibitor

Takeshi Yamamoto; Manabu Hori; Ikuo Watanabe; Hisayoshi Tsutsui; Shoji Ikeda; Hiroshi Ohtaka

Chemical & Pharmaceutical Bulletin | 1998

Synthesis and quantitative structure-activity relationships of N-(3-oxo-3,4-dihydro-2H-benzo[1,4]oxazine-6-carbonyl)guanidines as Na/H exchange inhibitors.

Takeshi Yamamoto; Manabu Hori; Ikuo Watanabe; Hisayoshi Tsutsui; Kengo Harada; Shoji Ikeda; Joji Maruo; Tominori Morita; Hiroshi Ohtaka

Chemical & Pharmaceutical Bulletin | 1997

Structural Requirements for Potent Na/H Exchange Inhibitors Obtained from Quantitative Structure-Activity Relationships of Monocyclic and Bicyclic Aroylguanidines

Takeshi Yamamoto; Manabu Hori; Ikuo Watanabe; Hisayoshi Tsutsui; Kengo Harada; Shoji Ikeda; Hiroshi Ohtaka

Chemical & Pharmaceutical Bulletin | 1998

A practical synthesis of N-(4-isopropyl-2,2-dimethyl-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazine-6-carbonyl)guanidine methanesulfonate (KB-R9032) utilizing potassium fluoride-alumina catalyzed N-alkylation

Takeshi Yamamoto; Manabu Hori; Ikuo Watanabe; Hisayoshi Tsutsui; Shoji Ikeda; Hiroshi Ohtaka

Archive | 1995

1,4-benzoxazine derivative, pharmaceutical composition containing the same and use thereof

Manabu Hori; Ikuo Watanabe; Hiroshi Ohtaka; Kengo Harada; Joji Maruo; Tominori Morita; Takeshi Yamamoto; Hisayoshi Tsutsui

Archive | 1995

1, 4-benzoxazine derivative and pharmaceutical compositions containing the same

Manabu Hori; Ikuo Watanabe; Hiroshi Ohtaka; Kengo Harada; Joji Maruo; Tominori Morita; Takeshi Yamamoto; Hisayoshi Tsutsui

Chemical & Pharmaceutical Bulletin | 1997

Design, Synthesis and Quantitative Structure-Activity Relationship Study of N-(3-Oxo-3, 4-dihydro-2H-benzo[1, 4]oxazine-7-carbonyl)guanidine Derivatives as Potent Na/H Exchange Inhibitors

Takeshi Yamamoto; Manabu Hori; Ikuo Watanabe; Hisayoshi Tsutsui; Kengo Harada; Shoji Ikeda; Joji Maruo; Tominori Morita; Hiroshi Ohtake

Chemical & Pharmaceutical Bulletin | 1991

Intramolecular Michael Reaction in Diastereoselective Synthesis of dl-Griseofulvin

Yasuo Takeuchi; Ikuo Watanabe; Hideo Tomozane; Kuniko Hashigaki; Masatoshi Yamato

Archive | 1997

Derives de benzo[1,4]thiazine et medicaments les contenant

Takeshi Yamamoto; Ikuo Watanabe; Kengo Harada; Shoji Ikeda

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Manabu Hori

Osaka University

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Kengo Harada

Shiga University of Medical Science

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Hiroshi Ohtaka

Organon International

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Tominori Morita

Osaka University

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Shoji Ikeda

Organon International

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Takeshi Yamamoto

Organon International

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Takeshi Yamamoto

Organon International

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Masatoshi Yamato

Okayama University

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Yasuo Takeuchi

Okayama University

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Hideo Tomozane

Okayama University

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