İlhan Metin Dağsuyu

Investigation of the Changes in the Positions of Upper and Lower Incisors, Overjet, Overbite, and Irregularity Index in Subjects with Different Depths of Curve of Spee

The aim of this study was to investigate the relationship between the depth of the curve of Spee and positions of upper and lower incisors, overjet, overbite, and anterior lower crowding. The material consisted of lateral head films and dental casts of 137 untreated adolescent subjects, 76 girls and 61 boys, aged 13 to 16 years. The subjects were divided into three groups with normal Spee, flat Spee, and deep Spee and were compared with one another. Differences between the Spee groups and between sexes were assessed by means of analysis of variance and a post hoc multiple comparison test. In addition, correlation coefficients between the depth of curve of Spee and other variables were calculated. Finally, cephalometric measurements for all subjects were subjected to a multiple regression analysis, with the depth of curve of Spee as the dependent variable. The results showed that there were no statistically significant differences in the positions of upper and lower incisors and anterior lower crowding among the Spee groups. However, overjet and overbite demonstrated significant differences among the groups. Statistically significant correlations were found between the depth of curve of Spee and overjet and overbite. Multiple linear regression analysis revealed that chronological age and all other variables used in the study could account for only 28.7% of the total variance of the curve of Spee. The overbite alone explained 17.3% of the total variance of the curvature.

Nonsurgical rapid maxillary expansion effects on craniofacial structures in young adult females. A bone scintigraphy study.

OBJECTIVE To evaluate the skeletal effects of nonsurgical rapid maxillary expansion (RME) on craniofacial structures with bone scintigraphy in young adult female subjects. MATERIALS AND METHODS The material of the present study consists of scintigraphic records taken from 17 early adult females treated with RME. All patients had a bilateral posterior crossbite, transverse maxillary deficiency, deep palatal vault, and dental crowding at the beginning of the treatment. The age range of the patients was 16.1 to 18.8 years, and the mean age was 17.3 +/- 0.86 years. Bone scintigraphy records were obtained before RME (T1), during the splitting of the midpalatal suture (T2), and after the end of active widening period (T3). Repeated measure analysis of variance was used to assess the differences between the periods. In addition, Bonferroni multiple comparison tests were applied to the measurements at which F values were found to be statistically significant. RESULTS According to the statistical analysis, significant activity changes were found in all regions studied and in all slices. The metabolic activity in all regions showed significant increases up to the separation of the midpalatal suture (T1-T2), whereas the metabolic activity exhibited a remarkable decrease (T2-T3) after the opening of the midpalatal suture. CONCLUSIONS Scintigraphic records revealed an increase in the regions of interest scores during RME in all regions and all slices. Therefore, it can be speculated that RME has had not only dental effects but also skeletal effects on young adult patients.

Evaluation of Oxidative Stress Biomarkers in Patients with Fixed Orthodontic Appliances

Aim. The aim of this study was to examine the changes in the levels of interleukine-1 beta (IL-1β), tumor necrosis factor alpha (TNF-α), malondialdehyde (MDA), nitric oxide (NO), and 8-hydroxydeoxyguanosine (8-OHdG) in saliva and IL-1β, TNF-α, and NO in gingival crevicular fluid (GCF) samples of patients with fixed orthodontic appliances. Material and Method. The subject population consisted of 50 volunteers who were in need of orthodontic treatment with fixed orthodontic appliances. GCF and saliva samples were obtained from all individuals before treatment, at 1st month of treatment and at 6th month of treatment. Periodontal clinical parameters were measured. Samples were investigated to detect IL-1β, TNF-α, and 8-OHdG levels using ELISA method and NO and MDA levels using spectrophotometric method. Results. Since IL-1β level detected in GCF at the 6th month of orthodontic treatment is statistically significant according to baseline (P < 0.05), all other biochemical parameters detected both in saliva and in GCF did not show any significant change at any measurement periods. Conclusion. Orthodontic tooth movement and orthodontic materials used in orthodontic treatment do not lead to a change above the physiological limits that is suggestive of oxidative damage in both GCF and saliva.