Ilona Nakoinz
Salk Institute for Biological Studies
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Featured researches published by Ilona Nakoinz.
Biochemical and Biophysical Research Communications | 1974
P. Ralph; Ilona Nakoinz; William C. Raschke
Summary A series of murine lymphosarcomas, including those induced by Abelson leukemia virus, were adapted to culture. Their cell growth was inhibited by B lymphocyte mitogens at concentrations which did not affect other hematopoietic cell lines: myelomas, T lymphomas, mastocytoma and erythroleukemia. The pattern of inhibition among different lymphosarcoma lines suggests that they represent tumors of B lymphocytes at different stages of differentiation.
Biochemical and Biophysical Research Communications | 1973
P. Ralph; R. Hyman; Ruth Epstein; Ilona Nakoinz; Melvin Cohn
Summary Thymic like lymphomas bear θ antigen and often TL antigen, and are killed by low concentrations of corticosteroids. These lymphomas are also very sensitive to killing by phytohemagglutinin and thymidine, in contrast to myelomas. Since θ and TL antigens and sensitivity to steroids and phytohemagglutinin change during the maturation of thymus cells to immunocompetent lymphocytes, these properties were studied in lymphoma variants. Variants selected for loss of detectable θ antigen or sensitivity to hydrocortisone, phytohemagglutinin, thymidine, thioguanine, or cyclic AMP still retain the unselected markers. This suggests that, although thymocyte properties appear to be coordinately regulated during differentiation, the expression of each may be altered by a separate mechanism.
Journal of Immunology | 1977
Peter J. Ralph; Ilona Nakoinz
Nature | 1975
Peter J. Ralph; Ilona Nakoinz
Cancer Research | 1977
Peter J. Ralph; Ilona Nakoinz
Journal of Immunology | 1973
James E. M. Watson; Ruth Epstein; Ilona Nakoinz; Peter Ralph
Journal of the National Cancer Institute | 1973
Peter Ralph; Ilona Nakoinz
Cancer Research | 1981
Peter J. Ralph; Ilona Nakoinz
Nature | 1974
Peter J. Ralph; Ilona Nakoinz
Journal of Immunology | 1982
Peter J. Ralph; N Williams; Ilona Nakoinz; Heather Jackson; J D Watson