In-Bai Chung

Effects of cytokines on VEGF expression and secretion by human first trimester trophoblast cell line

PROBLEM: The mechanism through which vascular endothelial growth factor (VEGF) regulation occurs at the feto‐maternal interface is poorly understood. The aim of this study was to investigate the effects of various cytokines on VEGF expression and secretion by trophoblast cells.

Immunohistochemical distribution of toll-like receptor 4 in preterm human fetal membrane.

Aim:  Toll‐like receptor 4 (TLR‐4) is the major receptor used for recognition of specific gram negative bacteria by the host immune system. The role of TLR‐4 has been revealed in preterm parturition. This study aims to demonstrate the immunohistochemical expression of TLR‐4 with regard to histological layers and anatomical regions of the human fetal membranes.