J.A. Prata

Apraclonidine and early postoperative intraocular hypertension after cataract extraction

Abstract The efficacy of topical 1% apraclonidine in controlling early postoperative IOP rise after cataract extraction was evaluated. Topical 1% apraclonidine was applied to 20 patients who underwent extracapsular cataract extraction with posterior intraocular lens implantation. On another 20 patients, who acted as control group a placebo (artificial tears) was given. The IOP was measured before preoperative medication and postoperatively at 6, 12 and 24 h, using the Perkins hand‐held applanation tonometer. In the control group, 9 patients (45%) developed intraocular hypertension and in the treated group only 2 (10%) showed hypertension, but with short duration and a moderate IOP rise. The difference in frequency of intraocular hypertension between the groups was statistically significant (p < 0.02). The statistical analysis showed that the postoperative IOP of operated treated eyes was significantly smaller than the IOP of operated control eyes. Furthermore, the postoperative IOP and the initial IOP did not differ statistically. The results of this study demonstrate the efficacy of topical apraclonidine 1% in controlling the early and transient intraocular hypertension following cataract extraction.

No changes in anatomical and functional glaucoma evaluation after trabeculectomy

PurposeTo assess the influence of glaucoma filtration surgery on anatomical and functional tests for glaucoma evaluation.MethodsTwenty-five eyes (25 patients) with primary open-angle glaucoma were evaluated, prospectively. Data were collected on vision acuity, intraocular pressure, standard automated perimetry, frequency doubling technology perimetry, scanning laser polarimetry (GDx) and confocal scanning laser ophthalmoscopy (HRT II) before and 3–6 months after surgery.ResultsMean (±SD) pre- and postoperative visual acuities (logMAR) were 0.28 (±0.18) and 0.30 (±0.17), respectively (P=0.346). In a mean time of 4.5 (±1.1) months after surgery, the mean preoperative intraocular pressure of 20.7 (±5.4) mmHg decreased to 11.04 (±2.52) mmHg (P<0.001). The results of the standard automated perimetry, frequency doubling technology perimetry, scanning laser polarimetry and confocal scanning laser ophthalmoscopy diagnostic methods revealed no significant difference (P>0.162) between pre and postoperative values and no significant correlation (P>0.296) between intraocular pressure reduction and value changes.ConclusionNo significant change on any test variable was detected after glaucoma filtration surgery. Trabeculectomy does not appear to influence standard automated perimetry, frequency doubling technology perimetry, scanning laser polarimetry and confocal scanning laser ophthalmoscopy (HRT II) results after a 4.5-month period of surgery in early to moderate glaucoma.

Impacto econômico no tratamento do glaucoma: volume de gotas de colírios antiglaucomatosos brasileiros e norte-americanos

Objetivo: Comparar o exame de gotas de colirios antiglaucomatosos norte-americanos e brasileiros, e a repercussao no custo do tratamento. Metodos: Estudo volumetrico da gota e consequente numero de gotas por mililitro, com estabelecimento da duracao media de cada frasco de colirio para a posologia e custo anual do tratamento. Resultados: A gota de Alphagan® brasileiro foi em media 18% maior que a norte-americana, com duracao media de 30,8 dias e custo anual de R

Comparação do volume da gota e custo do tratamento dos genéricos de maleato de timolol 0,5%

440,70; o Alphagana norte-americano teve duracao media de 36,3 dias e custo anual de R

Análise discriminante dos pacientes portadores de glaucoma primário de ângulo aberto através do exame de Doppler colorido e do campo visual

374,10, ou seja, 17,8% de diferenca no custo anual. A gota de Betoptic S® brasileiro foi 38,4% maior que a norte-americana, com duracao de 31,3 dias e custo anual de R

Lack of circadian change of concentration of C-type natriuretic peptide in rabbit aqueous humor

192,60; o Betoptic Sa norte-americano teve duracao de 43,3 dias e custo anual de R

Uso de membrana amniótica no tratamento de complicações pós-trabeculectomia

139,40, ou seja, 38,1% de diferenca no custo anual. A gota de Iopidine® brasileiro foi 46,3% maior que a norte-americana, com duracao de 35,7 dias e custo anual de R

Reprodutibilidade do exame de medida da camada de fibras nervosas da retina por meio da polarimetria de varredura a laser

365,00; o Iopidinea norte-americano teve duracao de 52,6 dias e custo anual de R

Influência da cicloplegia sobre a ação hipotensora do latanoprost em indivíduos normais

248,40, ou seja, 46,9% de diferenca no custo anual. A gota de Timoptol® foi 14,7% maior que a norte-americana, com duracao de 45,4 dias e custo anual de R

Pressäo intra-ocular na forma crônica da doença de Chagas

58,40; o Timoptica norte-americano teve duracao de 52,1 dias e custo anual de R