J.A. Shizuru
Stanford University
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Publication
Featured researches published by J.A. Shizuru.
Immunological Reviews | 1997
Hector L. Aguila; Koichi Akashi; Jos Domen; Kimberly L. Gandy; Eric Lagasse; Reina E. Mebius; Sean J. Morrison; J.A. Shizuru; Samuel Strober; Nobuko Uchida; Douglas E. Wright; Irving L. Weissman
Summary: We review the development of the hematopoietic system, focusing on the transition from hematopoietic stem cells (HSCs) to T cell This includes the isolation of HSCs, and recent progress in understanding their ontogeny, homing properties, and differentiation. HSC transplantation is reviewed, including the kinetics of reconstitution, engraftment across histocompatibility barriers, the facilitation of allogeneic engraftment, and the mechanisms of graft rejection. We describe progress in understanding T‐cell development in the bone marrow and thymus as well as the establishment of lymph nodes. Finally, the role of bcl‐2 in regulating homeostasis in the hematopoietic system is discussed.
American Journal of Respiratory and Critical Care Medicine | 2010
Serpil C. Erzurum; Sharon Rounds; Troy Stevens; Micheala A. Aldred; Jason M. Aliotta; Stephen L. Archer; Kewal Asosingh; Robert S. Balaban; Natalie N. Bauer; Jahar Bhattacharya; Harm J. Bogaard; Gaurav Choudhary; Gerald W. Dorn; Raed A. Dweik; Karen A. Fagan; Michael B. Fallon; Toren Finkel; Mark W. Geraci; Mark T. Gladwin; Paul M. Hassoun; Marc Humbert; Naftali Kaminski; Steven M. Kawut; Joseph Loscalzo; Donald M. McDonald; Ivan F. McMurtry; John H. Newman; Mark R. Nicolls; Marlene Rabinovitch; J.A. Shizuru
The Division of Lung Diseases of the National Heart, Lung, and Blood Institute, with the Office of Rare Diseases Research, held a workshop to identify priority areas and strategic goals to enhance and accelerate research that will result in improved understanding of the lung vasculature, translational research needs, and ultimately the care of patients with pulmonary vascular diseases. Multidisciplinary experts with diverse experience in laboratory, translational, and clinical studies identified seven priority areas and discussed limitations in our current knowledge, technologies, and approaches. The focus for future research efforts include the following: (1) better characterizing vascular genotype-phenotype relationships and incorporating systems biology approaches when appropriate; (2) advancing our understanding of pulmonary vascular metabolic regulatory signaling in health and disease; (3) expanding our knowledge of the biologic relationships between the lung circulation and circulating elements, systemic vascular function, and right heart function and disease; (4) improving translational research for identifying disease-modifying therapies for the pulmonary hypertensive diseases; (5) establishing an appropriate and effective platform for advancing translational findings into clinical studies testing; and (6) developing the specific technologies and tools that will be enabling for these goals, such as question-guided imaging techniques and lung vascular investigator training programs. Recommendations from this workshop will be used within the Lung Vascular Biology and Disease Extramural Research Program for planning and strategic implementation purposes.
Biology of Blood and Marrow Transplantation | 2007
Sally Arai; Bita Sahaf; Carol Jones; James L. Zehnder; Robert Lowsky; Samuel Strober; J.A. Shizuru; R. Negrin; Laura J. Johnston; Ginna G. Laport; Keith Goldstein; J. Brown; Linda Elder; Kathryn Tierney; Phillip W. Lavori; David B. Miklos
Biology of Blood and Marrow Transplantation | 2006
Georg-Nikolaus Franke; Ute Hegenbart; Dietger Niederwieser; Michael B. Maris; J.A. Shizuru; Monic J. Stuart; Hildegard Greinix; Catherine Cordonnier; Bernard Rio; Alois Gratwohl; Thoralf Lange; W. Poenisch; L. Grommisch; Haifa-Kathrin Al-Ali; Barry E. Storer; David G. Maloney; Effie W. Petersdorf; Peter A. McSweeney; T. Chauncey; Edward Agura; Elliot M. Epner; Richard T. Maziarz; Finn Bo Petersen; Benedetto Bruno; Rainer Storb
Biology of Blood and Marrow Transplantation | 2012
Mareike Florek; Emanuela Sega; A.M.S. Mueller; Dennis B. Leveson-Gower; J.A. Shizuru; Robert S. Negrin
Biology of Blood and Marrow Transplantation | 2012
A.M.S. Mueller; Jessica Poyser; Natascha J Kuepper; Cassandra E. Burnett; Holbrook Kohrt; Mareike Florek; Pei Zhang; Rose M. Ko; J.A. Shizuru
Journal of Immunology | 2011
Sussan Dejbakhsh-Jones; Kazuhiro Takahashi; Kent P. Jensen; Stephan Busque; John D. Scandling; J.A. Shizuru; Robert Lowsky; Edgar G. Engleman; Samuel Strober
Biology of Blood and Marrow Transplantation | 2011
A.M.S. Mueller; Mareike Florek; Husein Hadeiba; J.A. Shizuru
Biology of Blood and Marrow Transplantation | 2011
R.M. Ko; K. Logronio; A. Czechowicz; J.A. Shizuru
Biology of Blood and Marrow Transplantation | 2011
A.M.S. Mueller; Holbrook Kohrt; Ginna G. Laport; Robert S. Negrin; Steven Cha; Irving L. Weissman; J.A. Shizuru