J. Lachaine

Clinical and Economic Characteristics of Patients With Fibromyalgia Syndrome

ObjectivesFibromyalgia syndrome (FMS) is a chronic disorder defined by widespread muscle pain and multiple tender points. The objectives of this study were to estimate prevalence of comorbidities, healthcare resources utilization, and costs associated with FMS. MethodsA retrospective cohort study was conducted using data from the Quebec provincial health plans (RAMQ) for a random sample of patients with diagnoses of FMS and a control cohort of patients without FMS, matched for age and gender. Prevalence of comorbidities was estimated. Healthcare resources consumed by FMS and non-FMS patients were identified in terms of visits to physicians, physicians interventions, pain-related medications, nonpain-related medications, and hospitalizations. ResultsA total of 16,010 patients with 2 diagnoses of FMS were identified, and control patients were randomly selected with a ratio of 1:1. Incidence of most comorbidities was significantly higher in the FMS group and the chronic disease score (3.8 vs. 2.8; ANOVA P <0.001). The proportion of patients with at least 1 comorbidity was 87.4% in the FMS group and 60.1% in the control group (χ2P<0.001). The annual number of visits to physician and physicians interventions was 25.1 for FMS and 14.8 for non-FMS patients. The amount paid by the RAMQ was significantly higher for patients with FMS (

Economic Impact of Same-Day Home Discharge After Uncomplicated Transradial Percutaneous Coronary Intervention and Bolus-Only Abciximab Regimen

4065) compared with patients without FMS (

I-SAVE Study: Impact of Sedation, Analgesia, and Delirium Protocols Evaluated in the Intensive Care Unit: An Economic Evaluation

2766) (ANOVA P<0.001). DiscussionResults of this analysis of the RAMQ database illustrate the high prevalence of comorbidities among patients with a diagnosis of FMS and strongly indicate that the economic burden of FMS is substantial.

Risk of Clostridium difficile-associated disease among patients receiving proton-pump inhibitors in a Quebec medical intensive care unit.

OBJECTIVES This study sought to estimate the economic impact of same-day home discharge compared with overnight hospitalization after transradial percutaneous coronary intervention (PCI). BACKGROUND Same-day home discharge after transradial PCI and a bolus-only abciximab regimen was found to be clinically noninferior to the abciximab standard therapy and overnight hospitalization in patients with various forms of acute coronary syndromes. METHODS In the EASY (Early Discharge After Transradial Stenting of Coronary Arteries) trial, 1,005 patients were randomized after a bolus of abciximab and uncomplicated transradial coronary stenting, either to same-day home discharge and no infusion (outpatient group) or to overnight hospitalization and 12-h abciximab infusion (overnight-stay group). We estimated post-PCI health care cost (in Canadian dollars) of trial subjects and short-term economic impact of same-day home discharge. As randomization was done after the procedure, outcomes were similar, and PCI resource use showed minimal and nonsignificant differences, a post-PCI cost-minimization analysis was conducted. Detailed per-patient information of health care resources used immediately after PCI up to 30 days was collected. RESULTS Mean post-PCI hospital stay was 8.9 h for outpatients versus 26.5 h for overnight-stay patients (p < 0.001). At 30-day follow-up, the mean cumulative medical cost per outpatient was

Taking the lead: Community pharmacists' perception of their role potential within the primary care team

1,117 ±

Chemotherapy-induced emesis: quality of life and economic impact in the context of current practice in Canada.

1,554 versus

Systematic review of pharmacoeconomic studies of pharmacogenomic tests.

2,258 ±

Do proton-pump inhibitors increase the risk for nosocomial pneumonia in a medical intensive care unit?

1,328 for overnight-stay patients. The mean difference of

Medication adherence and persistence in the treatment of Canadian ulcerative colitis patients: analyses with the RAMQ database

1,141 (95% confidence interval:

Relationship between progression-free survival and overall survival in chronic lymphocytic leukemia: a literature-based analysis.

962 to