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Dive into the research topics where Jack R. Cooper is active.

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Featured researches published by Jack R. Cooper.


Experimental Biology and Medicine | 1949

Estimation of Dicumarol, 3, 31-Methylenebis (4-Hydroxycoumarin) in Biological Fluids.

Julius Axelrod; Jack R. Cooper; Bernard B. Brodie

Summary A simple and sensitive spectrophotometric method for the estimation of dicumarol in plasma and urine is described. Dicumarol is isolated from the biological material by extraction into heptane. The drug is returned to alkali and measured spectrophotometrically at 315 mν. The method is specific in that it does not include metabolic products of the drug.


Journal of Pharmacology and Experimental Therapeutics | 1955

THE ENZYMATIC METABOLISM OF HEXOBARBITAL (EVIPAL)

Jack R. Cooper; Bernard B. Brodie


Science | 1955

Detoxication of Drugs and Other Foreign Compounds by Liver Microsomes

Bernard B. Brodie; Julius Axelrod; Jack R. Cooper; Leo Gaudette; Bert N. La Du; Choco Mitoma; Sidney Udenfriend


Journal of Pharmacology and Experimental Therapeutics | 1954

INHIBITORY EFFECTS OF β-DIETHYLAMINOETHYL DIPHENYLPROPYLACETATE ON A VARIETY OF DRUG METABOLIC PATHWAYS IN VITRO

Jack R. Cooper; Julius Axelrod; Bernard B. Brodie


Journal of Pharmacology and Experimental Therapeutics | 1951

THE PHYSIOLOGICAL DISPOSITION AND CARDIAC EFFECTS OF PROCAINE AMIDE

Lester C. Mark; Herbert J. Kayden; J. Murray Steele; Jack R. Cooper; Irving Berlin; E. A. Rovenstine; Bernard B. Brodie


Journal of Pharmacology and Experimental Therapeutics | 1950

THE PHYSIOLOGICAL DISPOSITION OF DICUMAROL IN MAN

Murray Weiner; Shepard Shapiro; Julius Axelrod; Jack R. Cooper; Bernard B. Brodie


Journal of Pharmacology and Experimental Therapeutics | 1961

The enzymic oxidation of tryptophan to 5-hydroxytryptophan in the biosynthesis of serotonin.

Jack R. Cooper; Irving Melcer


Journal of Pharmacology and Experimental Therapeutics | 1960

THE ROLE OF ALCOHOL DEHYDROGENASE IN THE METABOLISM OF CHLORAL HYDRATE

Paul J. Friedman; Jack R. Cooper


Journal of Pharmacology and Experimental Therapeutics | 1957

ENZYMATIC OXIDATION OF PENTOBARBITAL AND THIOPENTAL

Jack R. Cooper; Bernard B. Brodie


Journal of Pharmacology and Experimental Therapeutics | 1965

THE ROLE OF THIAMINE IN NERVOUS TISSUE: EFFECT OF ANTIMETABOLITES OF THE VITAMIN ON CONDUCTION IN MAMMALIAN NONMYELINATED NERVE FIBERS

Christine J. Armett; Jack R. Cooper

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Julius Axelrod

National Institutes of Health

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Bert N. La Du

University of California

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Herbert J. Kayden

National Institutes of Health

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Sidney Udenfriend

Roche Institute of Molecular Biology

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