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Dive into the research topics where Jan A. Swinkels is active.

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Featured researches published by Jan A. Swinkels.


Psychological Medicine | 2007

Adjuvant occupational therapy for work-related major depression works : randomized trial including economic evaluation

Aart H. Schene; Maarten W. J. Koeter; Martijn Kikkert; Jan A. Swinkels; Paul McCrone

BACKGROUND Major depression has far-reaching consequences for work functioning and absenteeism. In most cases depression is treated by medication and clinical management. The addition of occupational therapy (OT) might improve outcome. We determined the cost-effectiveness of the addition of OT to treatment as usual (TAU). METHOD Sixty-two adults with major depression and a mean absenteeism of 242 days were randomized to TAU (out-patient psychiatric treatment) or TAU+OT [6 months, including (i) diagnostic phase with occupational history and work reintegration plan, and (ii) therapeutic phase with individual sessions and group sessions]. Main outcome domains were depression, work resumption, work stress and costs. Assessments were at baseline and at 3, 6, 12 and 42 months. RESULTS The addition of OT to TAU: (i) did not improve depression outcome, (ii) resulted in a reduction in work-loss days during the first 18 months, (iii) did not increase work stress, and (iv) had a 75.5% probability of being more cost-effective than TAU alone. CONCLUSION Addition of OT to good clinical practice does not improve depression outcome, improves productivity without increasing work stress and is superior to TAU in terms of cost-effectiveness.


The Journal of Clinical Psychiatry | 2006

Switching antidepressants after a first selective serotonin reuptake inhibitor in major depressive disorder: A systematic review

Henricus G. Ruhe; Jochanan Huyser; Jan A. Swinkels; Aart H. Schene


British Journal of Psychiatry | 2006

Dose escalation for insufficient response to standard-dose selective serotonin reuptake inhibitors in major depressive disorder: systematic review.

Henricus G. Ruhé; Jochanan Huyser; Jan A. Swinkels; Aart H. Schene


Aesthetic Surgery Journal | 2014

Evaluating the Psychopathological Profile of Women Undergoing Reduction Mammaplasty With the Symptom Checklist-90-Revised

Oren Lapid; Leonard U. M. Corion; Mark J. C. Smeulders; Jan A. Swinkels; Chantal M.A.M. van der Horst


Nuclear Medicine Communications | 2006

Switching Antidepressants After a First Selective Serotonin Reuptake Inhibitor in Major Depressive Disorder: A Systematic Review

Henricus G. Ruhe; Jochanan Huyser; Jan A. Swinkels; Aart H. Schene


Archive | 2001

Van experiment naar onderzoeksproject

Vries de J. G; Martijn Kikkert; Aart H. Schene; Jan A. Swinkels


Archive | 2011

disorder: Systematic review selective serotonin reuptake inhibitors in major depressive Dose escalation for insufficient response to standard-dose

Henricus G. Ruhé; Jochanan Huyser; Jan A. Swinkels; Aart Schene


Nuclear Medicine Communications | 2006

Dose escalation for insufficient response to standard-dose selective serotonin reuptake inhibitors in major depressive disorder - Systematic review

Henricus G. Ruhé; Jochanan Huyser; Jan A. Swinkels; Aart H. Schene


Tijdschrift Voor Kindergeneeskunde | 2005

Dosisverhoging en omschakeling liggen meest voor de hand

Henricus G. Ruhé; Jan A. Swinkels; Aart H. Schene


Archive | 2002

Ergotherapeutische interventie voor patienten met arbeidsgerelateerde depressie: een kosteneffectiviteitsstudie [2e herziene versie 2002]

Martijn Kikkert; Aart H. Schene; Jan A. Swinkels; Maarten W. J. Koeter

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Aart H. Schene

Radboud University Nijmegen

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Oren Lapid

University of Amsterdam

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