Jarir At Thobari

Compliance Pengguna Antihipertensi di RSUP DR. SARDJITO Yogyakarta (Periode Juli 2006- Juni 2009)

Hypertension is the second largest of the 10 diseases on an outpatient at a hospital in Indonesia. The poor compliance to therapy of hypertension is a major cause of uncontrolled blood pressure. The aim of this study is to determine compliance antihypertension on patient at DR. Sardjito hospital Yogyakarta. This study was designed with a retrospective cohort study design using a database of participants claimed prescribing health insurance (ASKES) in the DR. Sardjito hospital using antihypertensive drugs. Compliance measured with medication possession ratio (MPR). Data was analysed by chi- square and logistic regression statistic. From 8.011 patients, compliance of antihypertensive drugs during the first year is 7,6%. Analysis for compliance showed that the type of antihypertensive diuretics are more compliance compare with angiotensin II receptor blockers, ACE inhibitors, calcium channel blockers and beta blockers. Combination therapy (20,7%) is more compliance than monotherapy ( 4,1%), as well as drugs administration 1 time a day (8,2%) is more compliance than drug administration 2 times (2,5%) and 3 times a day (3%). The proportion of compliance in antihypertensive users at DR. Sardjito hospital classified as less good. Compliance pattern indicates that therapy is not continuous, the longer the use of antihypertensive therapy, the higher the discontinuous therapy.