Jason Bloxham
OSI Pharmaceuticals
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Publication
Featured researches published by Jason Bloxham.
Bioorganic & Medicinal Chemistry Letters | 2012
Patrick Hanrahan; Jimmy D. Bell; Gillian Bottomley; Stuart Bradley; Phillip Clarke; Eleanor Curtis; Susan Helen Davis; Graham Dawson; James Horswill; John Keily; Gary Moore; Chrystelle Marie Rasamison; Jason Bloxham
Substituted azaquinazolinones were identified as antagonists of the GHSr-1A receptor for the treatment of type II diabetes and obesity. Optimisation for potency and LogD lead to the identification of orally bioavailable, potent antagonists with improved selectivity over hERG.
Archive | 2005
Saleh Ahmed; Oscar Barba; Jason Bloxham; Graham Dawson; William Gattrell; John Kitchin; Neil Anthony Pegg; Imaad Saba; Shazia Sadiq; Smith Colin Peter Sambrook; Don Smyth; Arno G. Steinig; Robin Wilkes; Kenneth Foreman; Qinghua Felix Weng; Kathryn M. Stolz; Paula A. R. Tavares; Bijoy Panicker; An-Hu Li; Hanqing Dong; Lifu Ma; Matthew Cox
Archive | 2005
Jason Bloxham; Gary V. Borzillo; Eric William Collington; Shazia Sadiq; Smith Colin Peter Sambrook; Chris L. Waller; Graham Wynne
Archive | 2008
Jason Bloxham; Stuart Edward Bradley; Tom Banksia Dupree; Peter Timothy Fry; Patrick Hanrahan; Thomas Martin Krulle; Martin James Procter; Colin Peter Sambrook-Smith; Karen Lesley Schofield; Donald Smyth; Alan John William Stewart
Archive | 2011
Jason Bloxham; Stuart Edward Bradley; Colin Peter Sambrook-Smith; Donald Smyth; John Keily; Graham Dawson; Chrystelle Marie Rasamison; James Charles Bell
Archive | 2008
Jason Bloxham; Stuart Edward Bradley; Thomas Martin Krulle; Martin James Procter; Colin Peter Sambrook-Smith; Karen Lesley Schofield; Donald Smyth
Archive | 2005
Jason Bloxham; Matthew Colin Thor Fyfe; James Horswill; Revathy Perpetua Jeevaratnam; John Keily; Martin James Procter; Karen Lesley Schofield; Salam Shaaban; Simon Andrew Swain; Philippe Wong-Kai-In
Archive | 2005
Saleh Ahmed; Oscar Barba; Jason Bloxham; Graham Dawson; William Gattrell; John Kitchin; Neil Anthony Pegg; Imaad Saba; Shazia Sadiq; Colin Peter Sambrook Smith; Don Smyth; Amo G. Steinig; Robin Wilkes; Bijoy Panicker; Paula A. R. Tavares; Matthew Cox; An-Hu Li; Hanqing Dong; Lifu Ma; Kenneth Foreman; Qinghua Weng; Kathryn M. Stolz
Archive | 2008
Jason Bloxham; Stuart Edward Bradley; Thomas Martin Krulle; Martin James Procter; Colin Peter Sambrook-Smith; Karen Lesley Schofield; Donald Smyth
Archive | 2005
Jason Bloxham; Gary V. Borzillo; Eric William Collington; Shazia Sadiq; Smith Colin Peter Sambrook; Chris L. Waller; Graham Wynne
