Jay Prakash Sah

Prevalence of intestinal parasite among school children of Bharatpokhari V.D.C., Kaski, Nepal.

Aims: To determine the prevalence of the intestinal parasitic infection among school children and the factors associated with it. Study Design: Cross Sectional Place and Duration of Study: This study was conducted among school children in Bhulbhula Intermediate School, Janjyoti Primary School and Sukla Primary School of Bharatpokhari VDC, Kaski, western region of Nepal during December, 2012 to Feburary, 2013. Materials and Methods: A total of 163 faecal samples were collected. Samples were investigated under standard WHO guidelines for identification of parasites. Samples were analysed microscopically. Results: Out of the 163 children screened, the overall parasitic infection rate was found to be 18(11%). There was no statistically significant association between sex (p=0.935), schools (p=0.570) or age group (p=0.327) and the infection status. On the whole, Entamoeba histolytica (E.h) had the prevalence of 61.0% followed by Trichuris trichuria (TT) 22.0% and Hook worm, Ascaris/Giardia, Trichuris trichuria/Entamoeba histolytica 6.0% each. Conclusion: Results of this study indicates a low prevalence of intestinal parasite among school children in Bharatpokhari VDC, kaski, Western region of Nepal. Original Research Article British Microbiology Research Journal, 4(9): 1007-1012, 2014 1008

Development of Novel HIV Vaccine by Nano-biomaterials

Human immune deficiency virus is a life threatening immune deficiency disease causing virus. Nowadays Nano-Medicine is a promising field for manufacturing vaccines for various bacterial and viral diseases. FPCN containing specific antigen are capable to stimulate T-cell very well to kill the viruses. P24 is the capsid protein of HIV virus which can stimulate immune response. So FPCN containing p24 will be a good choice for HIV vaccination. The present hypothesis aimed to quantify the challenges of making a novel HIV vaccine using FPCN nano-particles.