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Dive into the research topics where Jean Gauthier is active.

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Featured researches published by Jean Gauthier.


Journal of Medicinal Chemistry | 2004

Non-nucleoside benzimidazole-based allosteric inhibitors of the hepatitis C virus NS5B polymerase: Inhibition of subgenomic hepatitis C virus RNA replicons in huh-7 cells

Pierre L. Beaulieu; Yves Bousquet; Jean Gauthier; James Gillard; Martin Marquis; Ginette McKercher; Charles Pellerin; Serge Valois; George Kukolj


Journal of Medicinal Chemistry | 1999

Ligands for the tyrosine kinase p56lck SH2 domain: discovery of potent dipeptide derivatives with monocharged, nonhydrolyzable phosphate replacements.

Pierre L. Beaulieu; Dale R. Cameron; Ferland Jm; Jean Gauthier; Elise Ghiro; James Gillard; Gorys; Martin Poirier; Jean Rancourt; Dominik Wernic; Montse Llinas-Brunet; Rajashehar Betageri; Mario G. Cardozo; Eugene R. Hickey; R. H. Ingraham; Scott Jakes; Alisa Kabcenell; Thomas M. Kirrane; Susan Lukas; Usha R. Patel; John R. Proudfoot; Rajiv Sharma; Liang Tong; Neil Moss


Antimicrobial Agents and Chemotherapy | 1998

Antiviral Activity of a Selective Ribonucleotide Reductase Inhibitor against Acyclovir-Resistant Herpes Simplex Virus Type 1 In Vivo

Jianmin Duan; Michel Liuzzi; William Paris; Michelle Lambert; Carol Lawetz; Neil Moss; Jorge Jaramillo; Jean Gauthier; Robert Deziel; Michael G. Cordingley


Journal of Medicinal Chemistry | 1996

Peptidomimetic Inhibitors of Herpes Simplex Virus Ribonucleotide Reductase with Improved in Vivo Antiviral Activity

Neil Moss; Pierre L. Beaulieu; Jean-Simon Duceppe; Jean-Marie Ferland; Michel Garneau; Jean Gauthier; Elise Ghiro; Sylvie Goulet; Ingrid Guse; Jorge Jaramillo; Montse Llinas-Brunet; Eric Malenfant; Raymond Plante; Martin Poirier; Francois Soucy; Dominik Wernic; Christiane Yoakim; Robert Deziel


Journal of Medicinal Chemistry | 1995

Peptidomimetic inhibitors of herpes simplex virus ribonucleotide reductase : a new class of antiviral agents

Neil Moss; Pierre L. Beaulieu; Jean-Simon Duceppe; Jean-Marie Ferland; Jean Gauthier; Elsie Ghiro; Sylvie Goulet; Louis Grenier; Montse Llinas-Brunet; Raymond Plante; Dominik Wernic; Robert Deziel


Journal of Heterocyclic Chemistry | 1985

Synthesis of novel imidazo[1,2‐a]pyrrolo[2,1‐c][1,4]benzodiazepines and pyrimido[1,2‐a]pyrrolo[2,1‐c][1,4]benzodiazepines

Jean‐Simon Duceppe; Jean Gauthier


Journal of Heterocyclic Chemistry | 1984

Synthesis of novel imidazo[1,2‐a][3,1]benzothiazines 4, imidazo[1,2‐a]‐[1,2,4]benzotriazines 5, and 4H‐imidazo[2,3‐c]pyrido[2,3‐e][1,4]oxazines 6

Jean Gauthier; Jean Simon Duceppe


Journal of Medicinal Chemistry | 1999

Phosphotyrosine-containing dipeptides as high-affinity ligands for the p56lck SH2 domain.

Montse Llinas-Brunet; Pierre L. Beaulieu; Dale R. Cameron; Jean-Marie Ferland; Jean Gauthier; Elise Ghiro; James Gillard; Vida Gorys; Martin Poirier; Jean Rancourt; Dominik Wernic; Raj Betageri; Mario G. Cardozo; Scott Jakes; Suzanne Lukas; Usha R. Patel; John R. Proudfoot; Neil Moss


Journal of Medicinal Chemistry | 1996

Ureido-based peptidomimetic inhibitors of herpes simplex virus ribonucleotide reductase: An investigation of inhibitor bioactive conformation

Neil Moss; Pierre L. Beaulieu; Jean-Simon Duceppe; Jean-Marie Ferland; Jean Gauthier; Elise Ghiro; Sylvie Goulet; Ingrid Guse; Montse Llinas-Brunet; Raymond Plante; Louis Plamondon; Dominik Wernic; Robert Deziel


Journal of Medicinal Chemistry | 2001

Nonpeptidic, monocharged, cell permeable ligands for the p56lck SH2 domain.

John R. Proudfoot; Rajashehar Betageri; Mario G. Cardozo; Thomas A. Gilmore; Susan L. Glynn; Eugene R. Hickey; Scott Jakes; Alisa Kabcenell; Thomas M. Kirrane; Annette K. Tibolla; Susan Lukas; Usha R. Patel; Rajiv Sharma; Mehran Yazdanian; Neil Moss; Pierre L. Beaulieu; Dale R. Cameron; Jean-Marie Ferland; Jean Gauthier; James Gillard; Vida Gorys; Martin Poirier; Jean Rancourt; Dominik Wernic; Montse Llinas-Brunet

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