Ji Hye Ha
Kangwon National University
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Publication
Featured researches published by Ji Hye Ha.
Journal of Bioscience and Bioengineering | 2009
Sung Ho Oh; Jae Gun Han; Young Myeong Kim; Ji Hye Ha; Seung Seop Kim; Myoung Hoon Jeong; Hyang Suk Jeong; Na-Young Kim; Jeong Sub Cho; Won Byong Yoon; Shin Young Lee; Do Hyung Kang; Hyeon Yong Lee
Autotrophic growth of Porphyridium cruentum under 18:12 h and 12:12 h light:dark cycles showed the maximum cell concentration of 2.1 g-dry wt./L, whereas the specific growth rate, 0.042 (1/h), at 18:6 h is faster than that of 12:12 h, 0.031 (1/h), respectively. The highest lipid accumulation level, 19.3 (%, w/w), was achieved at 12:12 h cycle. Under dark cultivation condition with 10 g/L of glucose, the lipid accumulation in the cell was 10.9 (%, w/w), whereas the heterotrophic growth with glycerol as the carbon resource showed low level of cell concentration and lipid production, compared to that of glucose. The glucose was decided to be a suitable carbon resource for the heterotrophic growth of P. cruentum. The lipids from P. cruentum seemed be feasible for biodiesel production, because over 30% of the lipid was C16-C(18:1). The cultivation time and temperature were important factors to increase the maximum cell concentration. Extending the cultivation time helps maintain the maximum cell concentration, and higher lipid accumulation was achieved at 25 degrees C, compared to 35 degrees C. The fed-batch cultures showed that, under the light condition, the specific production rate was slightly decreased to 0.4% lipid/g-dry wt./day at the later stage, whereas, under the dark condition, the specific production rate was maintained to be a maximum value of 1.1% lipid/g-dry wt./day, even in the later stage of cultivation. The results indicate that the heterotrophic or 12:12 h cyclic mixotrophic growth of P. cruentum could be used for the production of biodiesel in long-term fed-batch cultivation of P. cruentum.
Korean Journal of Medicinal Crop Science | 2011
Jin Ling; Ji Hye Ha; Yoon Yong Choi; Yong Chang Seo; Ji Seon Kim; Young Ock Kim; Seon Woo Cha; Jin Chul Kim; Hyeon Yong Lee
This study was performed to investigate the enhancement of cosmeceutical activities of Berberis koreana bark by different extraction processes. The extracts are WE (water extract at , control), USE (ultrasonification for 1 hours at with water), HPE (high pressure for 5 minutes at with water) and USE + HPE (ultrasonification process for 1 hours after high pressure for 5 minutes at with water), respectively. The cytotoxicity of the extracts was in the range of 24.02~26.94% at 1.0 mg/ml concentration. The USE + HPE showed the lowest cytotoxicity. Compared to the WE, total phenolic and flavonoid contents in the USE + HPE increased to 121.5% and 154.2%. The USE + HPE showed the highest activity at 1.0 mg/ml concentration in 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging, inhibition activity of xanthine oxidase and superoxide dismutase (SOD)-like test, respectively. Tyrosinase inhibition of WE, USE, HPE and USE + HPE at 1.0 mg/ml concentration was measured as 17.72, 19.62, 22.83 and 24.16%, respectively. Hyaluronidase inhibition activities of the USE + HPE were higher than 20.8%~29.5% of the WE. Our results suggested that the extracts from ultrasonification process after high pressure extraction has relatively high cosmeceutical activities, and that the bark of Berberis koreana could be considered as a candidate of new functional cosmetic agents.
Korean Journal of Medicinal Crop Science | 2009
Seung Seop Kim; Ji Hye Ha; Myoung Hoon Jeong; Ju Hee Ahn; Won Byung Yoon; Sung-Jin Park; Dong Ho Seong; Hyeon Yong Lee
Korean Journal of Medicinal Crop Science | 2009
Jae Gun Han; Min Chul Kwon; Ji Hye Ha; Hyang Suk Jeong; Young Kim; Myoung Hoon Jeong; Jin Chul Kim; Hyeon Yong Lee
Korean Journal of Medicinal Crop Science | 2009
Hyang Suk Jeong; Jae Gun Han; Ji Hye Ha; Young Kim; Sung Ho Oh; Seoung Seop Kim; Myoung Hoon Jeong; Geun Pyo Choi; Uk Yeon Park; Hyeon Yong Lee
Korean Journal of Medicinal Crop Science | 2009
Hyang Suk Jeong; Ji Hye Ha; Young Heui Kim; Sung Ho Oh; Seoung Seop Kim; Myoung Hoon Jeong; Hyeon Yong Lee
Korean Journal of Food Science and Technology | 2009
Ling Jin; Ji Hye Ha; Myoung Hoon Jeong; Eul Kwon Chung; Ae Ran Chung; Jin Chul Kim; Ju Hee Ahn; Hyeon Yong Lee
Korean Journal of Food Science and Technology | 2009
Jae Gun Han; Ji Hye Ha; Yeong Beom Choi; Jeong Lim Go; Do Hyung Kang; Hyeon Yong Lee
Korean Journal of Food Science and Technology | 2009
Sung Ho Oh; Jae Gun Han; Ji Hye Ha; Young Myeong Kim; Myoung Hoon Jeong; Seong Sub Kim; Hyang Suk Jeong; Geun Pyo Choi; Uk Yeon Park; Do Hyung Kang; Hyeon Yong Lee
韓國藥用作物學會誌 = Korean journal of medicinal crop science | 2008
Min Chul Kwon; Jae Gun Han; Ji Hye Ha; Sung Ho Oh; Ling Jin; Hyang Suk Jeong; Geun Pyo Choi; Baik Hwang; Hyeon Yong Lee