Jingquan Yang

Immobilized antibacterial peptides on polyethylene terephthalate non-woven fabrics and antibacterial activity evaluation

Two novel antibacterial materials were prepared by immobilizing antibacterial peptides protamine sulfate and polymyxin sulfate on polyethylene terephthalate (PET) non-woven fabrics in this study. The fabrics were surface modified by a chemical procedure to create carboxyl groups followed by grafting coupling agent and immobilization of peptide. Scanning electron microscopy images showed that there were no changes on the surface of the fabrics after treatment. X-ray photoelectron spectroscopy confirmed that protamine and polymyxin were successfully grafted on the surface of the PET fabrics. Antibacterial testing using the liquid droplet method showed that fabrics treated with both peptides had excellent antibacterial activity against Escherichia coli and Staphylococcus aureus.

One-pot fabrication and antimicrobial properties of novel PET nonwoven fabrics.

Recently, with the ever-growing demand for healthy living, more and more research is focused on materials capable of killing harmful microorganisms around the world. It is believed that designing such protective materials for hygienic and biomedical applications can benefit people in professional areas and daily life. Thus, in this paper, one novel kind of antibacterial poly(ethylene terephthalate) (PET) nonwoven fabrics was conveniently one-pot prepared, with the combined immobilization of two biological antimicrobial agents, i.e. ε-polylysine and natamycin, by using the soft methacrylate nonwoven fabrics adhesives. Then, the antimicrobial activities of the functional fabrics were investigated by using the standard shaking-flask method, showing excellent antibacterial efficiency (AE) against both Escherichia coli (8099) and Staphylococcus aureus (ATCC 6538) (AE > 99.99%) compared with untreated PET nonwoven fabrics. The anti-bioaerosol tests also showed similar trends. Meantime, scanning electron microscopy analysis indicated that the bacteria on the antibacterial PET appeared to be partly bacteriolyzed and showed much less viability than those on the pristine ones. Moreover, the long residual biocidal action of such modified PET fabrics was also evaluated, and the antibacterial activity of antibacterial fibers was unaffected by the 3 month artificially accelerated aging.

Preparation of a Novel Bio-Antibacterial PET Nonwoven Fabrics and Antibacterial Activity Evaluation

A novel antibacterial material (P-PET) was prepared by immobilizing ε-polylysine on polyethylene terephthalate (PET) nonwoven fabrics in this study. Surface modifications of the fabric were performed by chemically modified procedure: creating carboxyl groups onto PET surface, grafting coupling agent and immobilizing the ε-polylysine. Scanning electron microscopy (SEM) was used to analyze the surface morphology of the fabrics, while Toluidine blue method and X ray photoelectron spectroscopy (XPS) method were used to evaluate the grafting densities. The antibacterial activities of the P-PET were investigated by using the shaking-flask method. The electron micrographs showed that there were not any changes to the surface of the blank PET and modified fabrics. The results of XPS analysis confirmed that εε-polylysine was successfully grafted onto the surface of PET. The results of antibacterial experiments showed that P-PET fabrics had excellent antibacterial activity against Escherichia coli and Staphylococcus aureus, and that P-PET fabrics were stable in storage for at least two years.