Tao Tian

Immobilized antibacterial peptides on polyethylene terephthalate non-woven fabrics and antibacterial activity evaluation

Two novel antibacterial materials were prepared by immobilizing antibacterial peptides protamine sulfate and polymyxin sulfate on polyethylene terephthalate (PET) non-woven fabrics in this study. The fabrics were surface modified by a chemical procedure to create carboxyl groups followed by grafting coupling agent and immobilization of peptide. Scanning electron microscopy images showed that there were no changes on the surface of the fabrics after treatment. X-ray photoelectron spectroscopy confirmed that protamine and polymyxin were successfully grafted on the surface of the PET fabrics. Antibacterial testing using the liquid droplet method showed that fabrics treated with both peptides had excellent antibacterial activity against Escherichia coli and Staphylococcus aureus.

One-pot fabrication and antimicrobial properties of novel PET nonwoven fabrics.

Recently, with the ever-growing demand for healthy living, more and more research is focused on materials capable of killing harmful microorganisms around the world. It is believed that designing such protective materials for hygienic and biomedical applications can benefit people in professional areas and daily life. Thus, in this paper, one novel kind of antibacterial poly(ethylene terephthalate) (PET) nonwoven fabrics was conveniently one-pot prepared, with the combined immobilization of two biological antimicrobial agents, i.e. ε-polylysine and natamycin, by using the soft methacrylate nonwoven fabrics adhesives. Then, the antimicrobial activities of the functional fabrics were investigated by using the standard shaking-flask method, showing excellent antibacterial efficiency (AE) against both Escherichia coli (8099) and Staphylococcus aureus (ATCC 6538) (AE > 99.99%) compared with untreated PET nonwoven fabrics. The anti-bioaerosol tests also showed similar trends. Meantime, scanning electron microscopy analysis indicated that the bacteria on the antibacterial PET appeared to be partly bacteriolyzed and showed much less viability than those on the pristine ones. Moreover, the long residual biocidal action of such modified PET fabrics was also evaluated, and the antibacterial activity of antibacterial fibers was unaffected by the 3 month artificially accelerated aging.

Performance Research of Positive Pressure Bio-Protection Suit Polyurethane Antibacterial Composite Fabric

Objective To study performance of positive pressure bio-protection suit fabric composited with polyurethane antibacterial film on double-sided, and to evaluate the feasibility of developing the positive pressure bio-protection suit with the composite fabric. Methods: Testing such performance as physical, protective, decontamination and antibacterial properties of polyurethane antibacterial composite fabric by standard methods. Results: Physical performance and micro-organisms liquid penetration resistance of the composite fabric have reached related standards requirements, while performances have no significant changes after decontamination testing. And its inhibition rates to gram-positive and gram-negative bacteria were so good that could reach 99%. Conclusions: According to testing results, this kind of fabric is suitable for developing positive pressure bio-protection suits by its ideal performance indicators and its upstanding decontamination consumption, antibacterial, flexible and lightweight properties.

Study on an Air Filter Material Immobilized with Bio-Antimicrobials

Use of an air filter material combined with antibacterial agents is one of the most effective methods to resolve the problem of air filter contaminated by pathogenic microbes. ε-Polylysine and Natamycin are two biogenic antimicrobials that have been widely applied in recent years because of their high antibacterial efficiency, harmlessness to human body and environmental friendliness. In this paper, a novel antibacterial air filter material was prepared by immobilizing ε-Polylysine and Natamycin onto fiberglass high efficiency air filter media by acrylate adhesive bonding. The mechanical properties, aerosol filtration properties, and antibacterial properties were then evaluated. An improvement in the mechanical properties of the material prepared was seen compared to the untreated filter media. The filtration efficiency of the material prepared for particle aerosols and bioaerosols both greater than 99.997%. Antibacterial efficiency of the material prepared against Staphylococcus aureus and Escherichia coli in suspensions were both greater than 99.99% compared to the untreated filter media. The anti-mildew effect against Aspergillus niger in suspension was strong compared to the untreated filter media. Antibacterial efficiency of the material prepared against bacteria in bioaerosols was greater than 99.99%. Observed with Scanning Electron Microscope, most bacteria on antibacterial filter media appeared to be dead. Thus, antibacterial air filter material prepared by immobilizing bio-antimicrobials on fiberglass had a strong inhibitory effect against gram-positive bacteria, gram-negative bacteria and fungi, with no impairment of the intrinsic properties. This kind of material appears to be promising for application in air cleaning and biological protection fields.