Joakim Larsson
AstraZeneca
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Publication
Featured researches published by Joakim Larsson.
Bioorganic & Medicinal Chemistry Letters | 2010
Henric Olsson; Peter Sjö; Oguz Ersoy; Anna Kristoffersson; Joakim Larsson; Bo Nordén
A class of inhibitors of mitogen activated protein kinase-activated kinase 2 (MK2) was discovered via high-throughput screening. This compound class demonstrates activity against the enzyme with sub-microM IC(50) values, and suppresses LPS-induced TNFalpha levels in THP-1 cells. MK2 inhibition kinetic measurements indicated mixed binding approaching non-ATP competitive inhibition.
Archive | 2005
Malena Bengtsson; Joakim Larsson; Grigorios Nikitidis; Peter Storm; John Peter Bailey; Edward Jolyon Griffen; Jean-Claude Arnould; Thomas Geoffrey Colerick Bird
Archive | 2002
Joakim Larsson; Peter Sjö
Archive | 2003
Håkan Bladh; Tomas Klingstedt; Joakim Larsson; Karolina Lawitz; Matti Lepistö; Hans Lönn; Grigorios Nikitidis
Archive | 2004
Haakan Bladh; Joakim Larsson
Archive | 2003
Håkan Bladh; Tomas Klingstedt; Joakim Larsson; Karolina Lawitz; Matti Lepistö; Hans Lönn; Grigorios Nikitidis
Archive | 2002
Joakim Larsson; Peter Sjö
Archive | 2005
Håkan Bladh; Tomas Klingstedt; Joakim Larsson; Karolina Lawitz; Matti Lepistoe; Hans Loenn; Grigorios Nikitidis
Archive | 2005
Malena Bengtsson; Joakim Larsson; Grigorios Nikitidis; Peter Storm; John Peter Bailey; Edward Jolyon Griffen; Jean-Claude Arnould; Thomas Geoffrey Colerick Bird
Archive | 2005
Malena Bengtsson; Joakim Larsson; Grigorios Nikitidis; Peter Storm; John Peter Bailey; Edward Jolyon Griffen; Jean-Claude Arnould; Thomas Geoffrey Colerick Bird
