Joanne Zhung
Memorial Sloan Kettering Cancer Center
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Joanne Zhung.
International Journal of Radiation Oncology Biology Physics | 2009
Daniel R. Gomez; Joanne Zhung; Jennifer Gomez; Kelvin Chan; Abraham J. Wu; Suzanne L. Wolden; David G. Pfister; Ashok R. Shaha; Jatin P. Shah; Dennis H. Kraus; Richard J. Wong; Nancy Y. Lee
PURPOSE To present our single-institution experience of intensity-modulated radiotherapy (IMRT) for oral cavity cancer. METHODS AND MATERIALS Between September 2000 and December 2006, 35 patients with histologically confirmed squamous cell carcinoma of the oral cavity underwent surgery followed by postoperative IMRT. The sites included were buccal mucosa in 8, oral tongue in 11, floor of the mouth in 9, gingiva in 4, hard palate in 2, and retromolar trigone in 1. Most patients had Stage III-IV disease (80%). Ten patients (29%) also received concurrent postoperative chemotherapy with IMRT. The median prescribed radiation dose was 60 Gy. RESULTS The median follow-up for surviving patients was 28.1 months (range, 11.9-85.1). Treatment failure occurred in 11 cases as follows: local in 4, regional in 2, and distant metastases in 5. Of the 5 patients with distant metastases, 2 presented with dermal metastases. The 2- and 3-year estimates of locoregional progression-free survival, distant metastasis-free survival, disease-free survival, and overall survival were 84% and 77%, 85% and 85%, 70% and 64%, and 74% and 74%, respectively. Acute Grade 2 or greater dermatitis, mucositis, and esophageal reactions were experienced by 54%, 66%, and 40% of the patients, respectively. Documented late complications included trismus (17%) and osteoradionecrosis (5%). CONCLUSION IMRT as an adjuvant treatment after surgical resection for oral cavity tumors is feasible and effective, with promising results and acceptable toxicity.
American Journal of Clinical Oncology | 2009
Abraham J. Wu; Jennifer Gomez; Joanne Zhung; Kelvin Chan; Daniel R. Gomez; Suzanne L. Wolden; Michael J. Zelefsky; Jedd D. Wolchok; Richard D. Carvajal; Paul B. Chapman; Richard J. Wong; Ashok R. Shaha; Dennis H. Kraus; Jatin P. Shah; Nancy Y. Lee
Objectives:To present our single-institution experience with postoperative radiotherapy for mucosal melanoma of the head and neck. Methods:Between 1992 and 2007, 27 patients with mucosal melanoma of the head and neck underwent surgical resection followed by postoperative radiotherapy. Median age was 68 years (range: 45–89 years). Sites included were sinonasal in 24 patients, oral cavity in 2, and oropharynx in 1. All but 2 patients had stage I disease. Twenty-two patients received hypofractionated radiation. Radiation techniques were intensity-modulated radiation therapy in 13, 3-dimensional conformal in 4, and conventional in 10. Results:The median follow-up for living patients was 45 months (range: 24–122 months). The 3- and 5-year estimates of local progression-free, loco-regional progression-free, distant metastasis-free, and overall survival were: 47% and 35%; 34% and 22%; 30% and 24%; and 40% and 33%, respectively. Median time to local failure and distant metastasis was 32 and 14 months, respectively. Acute toxicities included 19% with grade 2 or higher mucositis. No late complications related to the optic structures were seen. Conclusions:Modern radiotherapeutic techniques including intensity-modulated radiation therapy appear feasible and well-tolerated in the postoperative treatment of head and neck mucosal melanoma. Unusual or serious late complications have not been observed despite extensive use of hypofractionated regimens. However, rates of local and distant failure remain high.
International Journal of Radiation Oncology Biology Physics | 2006
Fernando F. de Arruda; Dev R. Puri; Joanne Zhung; Ashwatha Narayana; Suzanne L. Wolden; Margie Hunt; Hilda E. Stambuk; David G. Pfister; Dennis H. Kraus; Ashok R. Shaha; Jatin P. Shah; Nancy Y. Lee
International Journal of Radiation Oncology Biology Physics | 2007
Nancy Y. Lee; Kelvin Chan; Justin E. Bekelman; Joanne Zhung; James Mechalakos; Ashwatha Narayana; Suzanne L. Wolden; Ennapadam Venkatraman; David G. Pfister; Dennis H. Kraus; Jatin P. Shah; Michael J. Zelefsky
International Journal of Radiation Oncology Biology Physics | 2007
Nancy Y. Lee; W. O’Meara; Kelvin Chan; Cesar Della-Bianca; James Mechalakos; Joanne Zhung; Suzanne L. Wolden; Ashwatha Narayana; Dennis H. Kraus; Jatin P. Shah; David G. Pfister
International Journal of Radiation Oncology Biology Physics | 2008
Daniel R. Gomez; Bradford S. Hoppe; Suzanne L. Wolden; Joanne Zhung; Snehal G. Patel; Dennis H. Kraus; Jatin P. Shah; Ronald Ghossein; Nancy Y. Lee
Cancer | 2009
Daniel R. Gomez; Nora Katabi; Joanne Zhung; Suzanne L. Wolden; Michael J. Zelefsky; Dennis H. Kraus; Jatin P. Shah; Richard J. Wong; Ronald Ghossein; Nancy Y. Lee
Journal of Clinical Oncology | 2005
F. F. de Arruda; Joanne Zhung; Ashwatha Narayana; Suzanne L. Wolden; David G. Pfister; V. Serrano; Dennis H. Kraus; Ashok R. Shaha; Jatin P. Shah; Nancy Y. Lee
International Journal of Radiation Oncology Biology Physics | 2006
Nancy Y. Lee; Kelvin Chan; Justin E. Bekelman; Joanne Zhung; Ashwatha Narayana; Suzanne L. Wolden; Jatin P. Shah; Dennis H. Kraus; David G. Pfister; Michael J. Zelefsky
International Journal of Radiation Oncology Biology Physics | 2006
Kelvin Chan; W. O’Meara; Joanne Zhung; J Mechalakos; Suzanne L. Wolden; Ashwatha Narayana; Dennis H. Kraus; Jatin P. Shah; David G. Pfister; Nancy Y. Lee