João Paulo dos Anjos Souza Barbosa

Nível de atividade física em indivíduos com doença arterial periférica: uma revisão sistemática

BACKGROUND: Individuals with peripheral artery disease (PAD) have reduced levels of physical activity. Studies on this theme have important methodological differences that vary in relation to the characteristics of the individuals, the instruments used to measure physical activity, the strategies employed to their classified level of physical activity and outcome measures. OBJECTIVE: To describe physical activity level of individuals with PAD and to analyze the influence of physical activity level in healthy markers in these patients. METHODS: Systematic review of original studies published, up to 2010 in MEDLINE, LILACS, and SciELO databases. RESULTS: Of the 16 articles included in this review, 94% were published from the year 2000. The method more used for quantification of the levels of physical activity was the accelerometer. It was verified lower physical activity level among the individuals with PAD in comparison with individuals without the disease. Among individuals with PAD, highest levels of physical activity were associated with better hemorheological, hemodynamic, and body composition indicators. CONCLUSION: Individuals with PAD have lower levels of physical activity than individuals without the disease. Among individuals with the disease, those who are more physically active have better health markers.

Predictors of walking capacity in peripheral arterial disease patients

OBJECTIVE: To estimate walking capacity in intermittent claudication patients through a prediction model based on clinical characteristics and the walking impairment questionnaire. METHODS: The sample included 133 intermittent claudication patients of both genders aged between 30 and 80 years. Data regarding clinical characteristics, the walking impairment questionnaire and treadmill walking test performance were obtained. Multiple regression modeling was conducted to predict claudication onset distance and total walking distance using clinical characteristics (age, height, mass, body mass index, ankle brachial index lower, gender, history of smoking and co-morbid conditions) and walking impairment questionnaire responses. Comparisons of claudication onset distance and total walking distance measured during treadmill tests and estimated by a regression equation were performed using paired t-tests. RESULTS: Co-morbid conditions (diabetes and coronary artery disease) and questions related to difficulty in walking short distances (walking indoors – such as around your house and walking 5 blocks) and at low speed (walking 1 block at average speed – usual pace) resulted in the development of new prediction models high significant for claudication onset distance and total walking distance (p<0.001). In addition, non-significant differences from the results obtained by the treadmill test and estimated by the current model (p>0.05) were observed. CONCLUSION: The current study demonstrated that walking capacity can be adequately estimated based on co-morbid conditions and responses to the walking impairment questionnaire.

Effects of Clustered Comorbid Conditions on Walking Capacity in Patients with Peripheral Artery Disease

BACKGROUND Comorbid conditions are known to increase cardiovascular risk in patients with peripheral artery disease (PAD). However, whether comorbid conditions affect walking capacity remains controversial. Previous studies have analyzed comorbidities separately, but they are known to occur in a clustered fashion in PAD patients. Therefore, the aim of this study was to analyze the influence of clustered comorbid conditions on walking capacity in PAD patients. METHODS This cross-sectional study included 415 PAD patients (155 women and 260 men with an average age of 63 years). Claudication distance and total walking distance were assessed with the graded maximal treadmill test. Medical histories of hypertension, diabetes, cerebrovascular disease (CVD), coronary artery disease (CAD), and chronic obstructive pulmonary disease (COPD) were obtained. Binary logistic regression was carried out to analyze whether clustered comorbid conditions were associated with walking capacity. RESULTS CVD was associated with lower total walking distance (odds ratio [OR] = 2.45; 95% confidence interval [CI]: 1.11-5.39). The cluster hypertension, diabetes, CVD, CAD, and COPD were associated with a lower claudication distance (OR = 7.63; 95% CI: 1.42-40.96). In addition, the clusters of CVD and hypertension (OR = 3.16; 95% CI: 1.38-7.23), CVD and CAD (OR = 3.46; 95% CI: 1.25-9.57), CVD, hypertension, and diabetes (OR = 11.38; 95% CI: 2.27-57.00) were associated with a lower total walking distance. CONCLUSIONS CVD was associated with walking impairment of IC patients and in particular when CVD is clustered with other comorbid conditions.

Reliability of the Baltimore Activity Scale Questionnaire for Intermittent Claudication.

We assessed the reliability of the Baltimore Activity Scale for Intermittent Claudication (BASIC) for the evaluation of physical activity levels in individuals with intermittent claudication. We also identify the characteristics of the patients that influence the reliability of this questionnaire. A total of 38 men and women with peripheral artery disease and symptoms of intermittent claudication participated in the study. BASIC was administered to patients by the same evaluator at 2 different visits, separated by 7 days. The concordance coefficient ranged from .43 (How often do you walk at a fast pace?) to .85 (What happens when you feel pain while you walk?). The concordance coefficient of BASIC total score was .60. Higher concordance coefficients were observed in women (.66 vs .55), in younger patients (.63 vs .56), and in patients with lower ankle–brachial index (.64 vs .55). The reliability of BASIC questionnaire ranged from moderate to good in patients with claudication.

Relationship between physical activity, physical fitness and multiple metabolic risk in youths from Muzambinho's study

Abstract Negative associations between physical activity (PA), physical fitness and multiple metabolic risk factors (MMRF) in youths from populations with low PA are reported. The persistence of this association in moderately-to highly active populations is not, however, well established. The aim of the present study was to investigate this association in a Brazilian city with high frequency of active youths. We assessed 122 subjects (9.9 ± 1.3 years) from Muzambinho city. Body mass index, waist circumference, glycaemia, cholesterolaemia, systolic and diastolic blood pressures were measured. Maximal handgrip strength and one-mile walk/run test were used. Leisure time PA was assessed by interview. Poisson regression was used in the analysis. The model explained 11% of the total variance. Only relative muscular strength and one-mile walk/run were statistically significant (p < .05). Those who needed more time to cover the one-mile walk/run test had an increased in metabolic risk of 11%, and those with greater strength reduced the risk by about 82%. In conclusion, children and youths from an active population who need less time to cover the one-mile walk/run test or who had greater muscular strength showed a reduced metabolic risk. These results suggest that even in children and youths with high leisure time PA, a greater aerobic fitness and strength might help to further reduce their MMRF.

Gastrointestinal stromal tumor of the stomach and hepatocellular carcinoma: An unusual association

Highlights • This is a case report of an association of a c-Kit positive gastrointestinal stromal tumor and a hepatocellular carcinoma in a non-cirrhotic patient.• Attending to this unusual association and the relevance for clinical diagnosis and treatment, the authors decided to publish this case report.

Triagem pré-participação em exercício físico em pacientes com doença arterial periférica

BACKGROUND: Exercise has been recommended as the main treatment for individuals with peripheral artery disease (PAD). However, since these individuals have increased cardiovascular risk, a cardiovascular assessment before onset of exercise program must be performed. OBJECTIVE: The purpose of this study was to compare the efficacy of two screening tools for identifying individuals with PAD. METHODS: Twenty-eight men and women with PAD, who answered the Physical Activity Readiness Questionnaire (PAR-Q) and the stratification of cardiovascular risk questionnaire (SCRQ). RESULTS: The PAR-Q results showed that question six (Has any physician recommended the use of blood pressure or cardiovascular medications?) had higher frequency of positive responses (82.1%). Considering all responses, five individuals had all negative answers (17.9%). The results of the SCRQ showed that the question 11 (Do you have leg cramps or burning sensation cramp when you walk?) and the 2nd (Have you ever been told by a physician you have high blood pressure?) showed higher frequency of positive responses (82.1%). According to the criteria for cardiovascular risk stratification, all individuals were considered to be at high cardiovascular risk. CONCLUSION: The PAR-Q questionnaire was not sensitive enough to identify all subjects with PAD. On the other hand, the SRCQ was more efficient in identifying the subjects with PAD. Therefore, the use of SRCQ for screening PAD patients is suggested.